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BMJ：昏迷危重患者的短期结果（系统回顾和荟萃分析）

2015-06-08 崔倩 译 MedSci原创

昏迷危重患者Meta分析
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意义：为了确定昏迷危重患者和他们的短期内成果（在重症监护病房和医院）以及从医院出院后的联系。    设计：系统评价和发表的研究报告荟萃分析。资料来源于PubMed，EMBASE，CINAHL，Cochrane Library，和PsychINFO，没有语言的限制，截止到2015年1月。    筛选研究的符合标准：如果发表的研究是前瞻性观察

意义：为了确定昏迷危重患者和他们的短期内成果（在重症监护病房和医院）以及从医院出院后的联系。
    
设计：系统评价和发表的研究报告荟萃分析。资料来源于PubMed，EMBASE，CINAHL，Cochrane Library，和PsychINFO，没有语言的限制，截止到2015年1月。
    
筛选研究的符合标准：如果发表的研究是前瞻性观察队列或者在成人重症监护病房的患者进行了评估与经过验证的昏迷筛选和评级系统的临床试验，如果昏迷和四个临床终点至少一个（死亡之间测量入院时，住院时间，机械通气时间和出院后的任何结果）有联系的即有资格列入研究。如果刚招募的患者有神经系统紊乱疾病，或患者因心脏手术或器官/组织移植或集中于镇静管理或酒精或药物戒断住进重症监护的被排除在外。通过研究特点，人群抽样，鉴定昏迷和结果来提取数据。随机效应模型和荟萃回归分析用于个别研究数据分析。
    
结果：42项研究中16595例患者中5280人（31.8％）被确定呼吸危重病人。与没有昏迷的对照患者相比，昏迷患者住院期间的死亡率明显较高（风险比2.19，94％置信区间1.78至2.70；P<0.001），以及在重症监护机械通气和住院时间较长的持续时间（标准平均差异分比为1.79，（95％置信区间 0.31至3.27；P<0.001），1.38（0.99至1.77；P<0.001），和0.97（0.61至1.33；P<0.001））。现有的研究表明昏迷和出院后的认知功能障碍有联系。
    
结论：患者近三分之一在重症监护病房发展为昏迷，并且这些患者是在住院期间死亡的风险增加，在医院时间较长，出院后认知功能有障碍。

原始出处：

Jorge I F Salluh, professor1, Han Wang, specialist researcher2, Eric B Schneider, assistant professor2, Neeraja Nagaraja, postdoctoral research fellow2, Gayane Yenokyan, assistant scientist3, Abdulla Damluji, postdoctoral fellow4, Rodrigo B Serafim, assistant professor15, Robert D Stevens, associate professor6,Outcome of delirium in critically ill patients: systematic review and meta-analysis,BMJ,2015.6.2

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    2016-05-23 fangcong

    #荟萃分析#

    0

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    2016-01-04 gaoxiaoe

    #BMJ#

    0

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    2016-01-21 仁心济世

    #荟萃#

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1836866, encodeId=2d91183686639, content=<a href='/topic/show?id=1f188e230c5' target=_blank style='color:#2F92EE;'>#荟萃分析#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87230, encryptionId=1f188e230c5, topicName=荟萃分析)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b79433, createdName=fangcong, createdTime=Mon May 23 04:30:00 CST 2016, time=2016-05-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1847679, encodeId=a54f184e679fb, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Mon Jan 04 01:30:00 CST 2016, time=2016-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1681282, encodeId=35f9168128245, content=<a href='/topic/show?id=366b8e2299e' target=_blank style='color:#2F92EE;'>#荟萃#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87229, encryptionId=366b8e2299e, topicName=荟萃)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=仁心济世, createdTime=Thu Jan 21 03:30:00 CST 2016, time=2016-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=29069, encodeId=ec752906910, content=很好的知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=149, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=51a41609947, createdName=jiaoaoxiaoxu, createdTime=Thu Jun 25 21:32:00 CST 2015, time=2015-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=28179, encodeId=4bac281e934, content=恩，学习了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=146, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6edd1623158, createdName=a6300, createdTime=Fri Jun 19 08:55:00 CST 2015, time=2015-06-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1429467, encodeId=6193142946e94, content=<a href='/topic/show?id=26d559642f9' target=_blank style='color:#2F92EE;'>#昏迷#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59642, encryptionId=26d559642f9, topicName=昏迷)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=81fb4200032, createdName=wgx307, createdTime=Wed Jun 10 02:30:00 CST 2015, time=2015-06-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1576389, encodeId=e75115e6389db, content=<a href='/topic/show?id=e02ee6901a2' target=_blank style='color:#2F92EE;'>#系统回顾#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76901, encryptionId=e02ee6901a2, topicName=系统回顾)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=27e316318097, createdName=ms5822920152752585, createdTime=Wed Jun 10 02:30:00 CST 2015, time=2015-06-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=26677, encodeId=e936266e7a4, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Tue Jun 09 19:14:00 CST 2015, time=2015-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=26489, encodeId=69ef2648957, content=之前的相关研究少吗，又没做亚组分析。, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3b2c1627329, createdName=owlhealth, createdTime=Tue Jun 09 08:14:00 CST 2015, time=2015-06-09, status=1, ipAttribution=)]
    2015-06-25 jiaoaoxiaoxu

    很好的知识

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1836866, encodeId=2d91183686639, content=<a href='/topic/show?id=1f188e230c5' target=_blank style='color:#2F92EE;'>#荟萃分析#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87230, encryptionId=1f188e230c5, topicName=荟萃分析)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b79433, createdName=fangcong, createdTime=Mon May 23 04:30:00 CST 2016, time=2016-05-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1847679, encodeId=a54f184e679fb, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Mon Jan 04 01:30:00 CST 2016, time=2016-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1681282, encodeId=35f9168128245, content=<a href='/topic/show?id=366b8e2299e' target=_blank style='color:#2F92EE;'>#荟萃#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87229, encryptionId=366b8e2299e, topicName=荟萃)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=仁心济世, createdTime=Thu Jan 21 03:30:00 CST 2016, time=2016-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=29069, encodeId=ec752906910, content=很好的知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=149, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=51a41609947, createdName=jiaoaoxiaoxu, createdTime=Thu Jun 25 21:32:00 CST 2015, time=2015-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=28179, encodeId=4bac281e934, content=恩，学习了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=146, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6edd1623158, createdName=a6300, createdTime=Fri Jun 19 08:55:00 CST 2015, time=2015-06-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1429467, encodeId=6193142946e94, content=<a href='/topic/show?id=26d559642f9' target=_blank style='color:#2F92EE;'>#昏迷#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59642, encryptionId=26d559642f9, topicName=昏迷)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=81fb4200032, createdName=wgx307, createdTime=Wed Jun 10 02:30:00 CST 2015, time=2015-06-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1576389, encodeId=e75115e6389db, content=<a href='/topic/show?id=e02ee6901a2' target=_blank style='color:#2F92EE;'>#系统回顾#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76901, encryptionId=e02ee6901a2, topicName=系统回顾)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=27e316318097, createdName=ms5822920152752585, createdTime=Wed Jun 10 02:30:00 CST 2015, time=2015-06-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=26677, encodeId=e936266e7a4, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Tue Jun 09 19:14:00 CST 2015, time=2015-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=26489, encodeId=69ef2648957, content=之前的相关研究少吗，又没做亚组分析。, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3b2c1627329, createdName=owlhealth, createdTime=Tue Jun 09 08:14:00 CST 2015, time=2015-06-09, status=1, ipAttribution=)]
    2015-06-19 a6300

    恩，学习了。

    0

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    2015-06-10 wgx307

    #昏迷#

    0

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    2015-06-10 ms5822920152752585

    #系统回顾#

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1836866, encodeId=2d91183686639, content=<a href='/topic/show?id=1f188e230c5' target=_blank style='color:#2F92EE;'>#荟萃分析#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87230, encryptionId=1f188e230c5, topicName=荟萃分析)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b79433, createdName=fangcong, createdTime=Mon May 23 04:30:00 CST 2016, time=2016-05-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1847679, encodeId=a54f184e679fb, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Mon Jan 04 01:30:00 CST 2016, time=2016-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1681282, encodeId=35f9168128245, content=<a href='/topic/show?id=366b8e2299e' target=_blank style='color:#2F92EE;'>#荟萃#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87229, encryptionId=366b8e2299e, topicName=荟萃)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=仁心济世, createdTime=Thu Jan 21 03:30:00 CST 2016, time=2016-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=29069, encodeId=ec752906910, content=很好的知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=149, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=51a41609947, createdName=jiaoaoxiaoxu, createdTime=Thu Jun 25 21:32:00 CST 2015, time=2015-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=28179, encodeId=4bac281e934, content=恩，学习了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=146, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6edd1623158, createdName=a6300, createdTime=Fri Jun 19 08:55:00 CST 2015, time=2015-06-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1429467, encodeId=6193142946e94, content=<a href='/topic/show?id=26d559642f9' target=_blank style='color:#2F92EE;'>#昏迷#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59642, encryptionId=26d559642f9, topicName=昏迷)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=81fb4200032, createdName=wgx307, createdTime=Wed Jun 10 02:30:00 CST 2015, time=2015-06-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1576389, encodeId=e75115e6389db, content=<a href='/topic/show?id=e02ee6901a2' target=_blank style='color:#2F92EE;'>#系统回顾#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76901, encryptionId=e02ee6901a2, topicName=系统回顾)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=27e316318097, createdName=ms5822920152752585, createdTime=Wed Jun 10 02:30:00 CST 2015, time=2015-06-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=26677, encodeId=e936266e7a4, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Tue Jun 09 19:14:00 CST 2015, time=2015-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=26489, encodeId=69ef2648957, content=之前的相关研究少吗，又没做亚组分析。, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3b2c1627329, createdName=owlhealth, createdTime=Tue Jun 09 08:14:00 CST 2015, time=2015-06-09, status=1, ipAttribution=)]
    2015-06-09 huaxipanxing

    看看

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1836866, encodeId=2d91183686639, content=<a href='/topic/show?id=1f188e230c5' target=_blank style='color:#2F92EE;'>#荟萃分析#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87230, encryptionId=1f188e230c5, topicName=荟萃分析)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b79433, createdName=fangcong, createdTime=Mon May 23 04:30:00 CST 2016, time=2016-05-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1847679, encodeId=a54f184e679fb, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Mon Jan 04 01:30:00 CST 2016, time=2016-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1681282, encodeId=35f9168128245, content=<a href='/topic/show?id=366b8e2299e' target=_blank style='color:#2F92EE;'>#荟萃#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87229, encryptionId=366b8e2299e, topicName=荟萃)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=仁心济世, createdTime=Thu Jan 21 03:30:00 CST 2016, time=2016-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=29069, encodeId=ec752906910, content=很好的知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=149, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=51a41609947, createdName=jiaoaoxiaoxu, createdTime=Thu Jun 25 21:32:00 CST 2015, time=2015-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=28179, encodeId=4bac281e934, content=恩，学习了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=146, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6edd1623158, createdName=a6300, createdTime=Fri Jun 19 08:55:00 CST 2015, time=2015-06-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1429467, encodeId=6193142946e94, content=<a href='/topic/show?id=26d559642f9' target=_blank style='color:#2F92EE;'>#昏迷#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59642, encryptionId=26d559642f9, topicName=昏迷)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=81fb4200032, createdName=wgx307, createdTime=Wed Jun 10 02:30:00 CST 2015, time=2015-06-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1576389, encodeId=e75115e6389db, content=<a href='/topic/show?id=e02ee6901a2' target=_blank style='color:#2F92EE;'>#系统回顾#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76901, encryptionId=e02ee6901a2, topicName=系统回顾)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=27e316318097, createdName=ms5822920152752585, createdTime=Wed Jun 10 02:30:00 CST 2015, time=2015-06-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=26677, encodeId=e936266e7a4, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Tue Jun 09 19:14:00 CST 2015, time=2015-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=26489, encodeId=69ef2648957, content=之前的相关研究少吗，又没做亚组分析。, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3b2c1627329, createdName=owlhealth, createdTime=Tue Jun 09 08:14:00 CST 2015, time=2015-06-09, status=1, ipAttribution=)]
    2015-06-09 owlhealth

    之前的相关研究少吗，又没做亚组分析。

    0