JACC:非心脏手术后出现围手术期心肌梗死的死亡率高

2016-07-19 Mechront 译 MedSci原创

近期发表在Journal of the American College of Cardiology的研究称,非心脏手术后出现围手术期心肌梗死的患者有很高的死亡率,即使他们接受PCI治疗。佛蒙特大学医学中心的Harold L. Dauerman博士对1093例在克利夫兰诊所进行非心脏手术、术后7天内出现围手术期心肌梗死的患者数据进行了分析研究。随访3832人年。接受PCI的患者中有281名为ST段

近期发表在Journal of the American College of Cardiology的研究称,非心脏手术后出现围手术期心肌梗死的患者有很高的死亡率,即使他们接受PCI治疗。

佛蒙特大学医学中心的Harold L. Dauerman博士对1093例在克利夫兰诊所进行非心脏手术、术后7天内出现围手术期心肌梗死的患者数据进行了分析研究。随访3832人年。接受PCI的患者中有281名为ST段抬高型心肌梗死(STEMI),241名为非STEMI。

研究人员发现,在总人口中,30天的死亡率为5.2%,1年死亡率为15%。在PCI人群中,30天的死亡率为11.3%。PCI中的STEMI亚组,30天死亡率为31.2 %,非STEMI亚组,30天死亡率为8.5%。

PCI术后30天死亡率相关的预测因素有:出血事件(OR = 4.33; 95% CI, 1.52-12.3)、肌钙蛋白T峰值水平(OR = 1.2; 95% CL, 1.08-1.34)、潜在的外周血管疾病(OR = 4.86; 95% CL, 1.66-14.22)。

长期死亡率预测因素有:年龄(HR = 1.03; 95% CL, 1.01-1.04)、出血(HR = 2.31; 95% CL, 1.61-3.32)、肾功能不全(HR = 2.26; 95% CL, 1.51-3.39) 、血管手术(HR = 1.48; 95% CL, 1.02-2.15)。

研究者写道,目前的结果表明,非心脏手术后出现围手术期心肌梗死,不管患者有没有进行PCI,均有很高的死亡率。

原始出处:


Dauerman HL. The Expanding Universe of Perioperative Myocardial Infarction.J Am Coll Cardiol. 2016;doi:10.1016/j.jacc.2016.03.601.

Perioperative MI after noncardiac surgery linked to high death rates even if PCI performed.
Healio.July 18, 2016

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    2016-09-20 hbwxf
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createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Tue Jul 19 16:58:00 CST 2016, time=2016-07-19, status=1, ipAttribution=)]
  5. 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time=2016-07-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1488265, encodeId=e39614882652f, content=<a href='/topic/show?id=f37799413a6' target=_blank style='color:#2F92EE;'>#非心脏手术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99413, encryptionId=f37799413a6, topicName=非心脏手术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Thu Jul 21 02:15:00 CST 2016, time=2016-07-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93682, encodeId=ed2f93682a5, content=好文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Tue Jul 19 16:58:00 CST 2016, time=2016-07-19, status=1, ipAttribution=)]
    2016-09-25 1e10c84am36(暂无匿称)

    文章很好值得关注

    0

  6. 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time=2016-07-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1488265, encodeId=e39614882652f, content=<a href='/topic/show?id=f37799413a6' target=_blank style='color:#2F92EE;'>#非心脏手术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99413, encryptionId=f37799413a6, topicName=非心脏手术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Thu Jul 21 02:15:00 CST 2016, time=2016-07-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93682, encodeId=ed2f93682a5, content=好文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Tue Jul 19 16:58:00 CST 2016, time=2016-07-19, status=1, ipAttribution=)]
    2016-09-11 1e10c84am36(暂无匿称)

    己拜读,受益匪浅

    0

  7. 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    2016-07-19 doctorJiangchao

    好文章

    0

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