Clin Gastroenterology H:停止吸烟可以降低无柄锯齿状息肉的发生率

2019-07-14 不详 MedSci原创

研究人员在本项研究中调查了无症状锯齿状息肉(SSPs)的患病率以及无症状年轻人中SSP风险与可改变生活方式因素之间的关系。

背景与目的
研究人员在本项研究中调查了无症状锯齿状息肉(SSPs)的患病率以及无症状年轻人中SSP风险与可改变生活方式因素之间的关系。

方法
研究人员使用筛查结肠镜检查数据库进行了横断面研究,该数据库包括13618名年龄在30至49岁之间的无症状受试者,以及17999名年龄在50至75岁之间的受试者。我们通过对包括吸烟和饮酒的临床数据的多变量分析来研究SSP的风险因素。

结果
在30至49岁的受试者中,SSP的患病率为2.0%(13618人中有275人发病)。在所有SSP中,40.7%(275个SSP中的112个)无柄锯齿状息肉很大(≥10mm)。吸烟每天1包或更多包年与总体SSP相关(比值比[OR],1.87; 95%CI,1.17-2.99)。远端SSP的解剖位置与吸烟年龄之间的关联强于近端SSP(OR,2.71; 95%CI,1.27-5.77 vs OR,1.60; 95%CI,1.00-2.54)。停止吸烟5年或更长时间可降低SSP(OR,0.49; 95%CI,0.28-0.86)的风险。

结论
本项研究发现在无症状的年轻人中,吸烟与SSP发生相关。停止吸烟可降低SSP的风险。

原始出处:

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    2019-12-09 许安
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