Metabolism:肉桂,能助你燃烧脂肪!

2017-11-25 中国生物技术网 佚名

美国密歇根大学生命科学研究所(LSI)的一项新研究发现,肉桂皮这种常用的香料或许能够对抗肥胖。

美国密歇根大学生命科学研究所(LSI)的一项新研究发现,肉桂皮这种常用的香料或许能够对抗肥胖。

科学家们过去观察到,肉桂醛能够使小鼠免于肥胖和高血糖症。但是这种作用背后的机制在当时并不明确。肉桂醛是赋予肉桂皮具有香味的精油,是一种醛类有机化合物,为黄色黏稠状液体,大量存在于肉桂等植物体内。

肉桂醛分子结构式

LSI助理教授Jun Wu的实验室中的研究人员想要更好地理解肉桂醛的作用,并确定它是否对人类也同样有保护作用。

Wu说:“科学家们发现,这种物质能够影响代谢,所以我们想要弄清楚是哪种生物途径以及其如何参与其中,它在小鼠和人类细胞中是否相同。”

这项研究发表在《Metabolism》的12月刊上。研究结果表明,肉桂醛能够改善代谢健康,它直接作用于脂肪细胞,通过一种称为产热的过程,开始燃烧能量,从而改善代谢健康。

Wu和同事们对人类志愿者的脂肪细胞进行了测试,涵盖各个年龄段、种族以及身体质量指数。当研究人员用肉桂醛作用于脂肪细胞时,他们发现,某些加强脂质代谢的基因和酶的表达增加了。他们还观察到Ucp1和Fgf21的增加,这是参与产热的重要代谢调节蛋白。

脂肪细胞通常以脂质的形式存储能量。这种长期存储方式对于人类祖先是有益的,那时的人类能够获取的高脂肪食物很少,因此有巨大的需求存储脂肪。这些脂肪可以在饥饿或寒冷的时候被使用,脂质会将储存的能量转化为热量。

Wu说:“直到很近的时代能量过剩才成为一个问题。在整个进化过程中,能量缺乏一直是主要问题。所以任何消耗能量的过程通常都会在身体不需要的时候关闭产热作用。”

随着肥胖趋势日渐明显,和Wu一样的研究人员们开始寻找促使脂肪细胞激活产热作用的方法,从而使那些燃烧脂肪的过程重新开始。

Wu相信,肉桂醛能够提供这种激活作用。因为它已经被广泛用于食品行业。因此,相比于采用传统的药物治疗,患者更容易采纳基于肉桂的疗法。

Wu说:“肉桂进入人类的饮食已经有数千年历史,人们普遍喜欢它。如果它能够对抗肥胖,那么对患者来说应该非常容易接受这种代谢健康疗法。”

如果现在就想依靠大量的肉桂来甩掉假日里增长的肥肉,还为时过早,Wu提醒说,还需要进一步的研究来确定如何在不引起任何副作用的前提下最好地控制肉桂醛对代谢带来的益处。

原始出处:
Jiang J, Emont MP, Jun H,et al.Cinnamaldehyde induces fat cell-autonomous thermogenesis and metabolic reprogramming.Metabolism. 2017 Dec;77:58-64. doi: 10.1016/j.metabol.2017.08.006. Epub 2017 Sep 1.

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    2018-05-31 guojianrong
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    2018-09-30 gujh
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    2018-10-18 一闲
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  5. [GetPortalCommentsPageByObjectIdResponse(id=1887779, encodeId=be7f188e7790f, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Thu May 31 20:27:00 CST 2018, time=2018-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1935308, encodeId=dd7c1935308ab, content=<a href='/topic/show?id=e31a6e35866' target=_blank style='color:#2F92EE;'>#燃烧脂肪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67358, encryptionId=e31a6e35866, topicName=燃烧脂肪)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3333505, createdName=gujh, createdTime=Sun Sep 30 10:27:00 CST 2018, time=2018-09-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1896210, encodeId=b8e51896210c3, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Thu Oct 18 20:27:00 CST 2018, time=2018-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1577182, encodeId=610e15e7182e2, content=<a href='/topic/show?id=d86d1159e36' target=_blank style='color:#2F92EE;'>#Metabolism#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11597, encryptionId=d86d1159e36, topicName=Metabolism)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a6516392333, createdName=1249859em43(暂无昵称), createdTime=Mon Nov 27 08:27:00 CST 2017, time=2017-11-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1597987, encodeId=309d159e98794, content=<a href='/topic/show?id=6c6f1e62c5' target=_blank style='color:#2F92EE;'>#ABO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1762, encryptionId=6c6f1e62c5, topicName=ABO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b6c918580135, createdName=闆锋旦, createdTime=Mon Nov 27 08:27:00 CST 2017, time=2017-11-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=264580, encodeId=5161264580c4, content=温阳助火.都可以增加代谢.从而减肥, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c4a5105539, createdName=lovetcm, createdTime=Sun Nov 26 21:45:56 CST 2017, time=2017-11-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=264245, encodeId=d7cc264245e9, content=学习了.好文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Sat Nov 25 18:59:12 CST 2017, time=2017-11-25, status=1, ipAttribution=)]
    2017-11-27 闆锋旦
  6. [GetPortalCommentsPageByObjectIdResponse(id=1887779, encodeId=be7f188e7790f, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Thu May 31 20:27:00 CST 2018, time=2018-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1935308, encodeId=dd7c1935308ab, content=<a href='/topic/show?id=e31a6e35866' target=_blank style='color:#2F92EE;'>#燃烧脂肪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67358, encryptionId=e31a6e35866, topicName=燃烧脂肪)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3333505, createdName=gujh, createdTime=Sun Sep 30 10:27:00 CST 2018, time=2018-09-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1896210, encodeId=b8e51896210c3, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Thu Oct 18 20:27:00 CST 2018, time=2018-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1577182, encodeId=610e15e7182e2, content=<a href='/topic/show?id=d86d1159e36' target=_blank style='color:#2F92EE;'>#Metabolism#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11597, encryptionId=d86d1159e36, topicName=Metabolism)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1a6516392333, createdName=1249859em43(暂无昵称), createdTime=Mon Nov 27 08:27:00 CST 2017, time=2017-11-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1597987, encodeId=309d159e98794, content=<a href='/topic/show?id=6c6f1e62c5' target=_blank style='color:#2F92EE;'>#ABO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1762, encryptionId=6c6f1e62c5, topicName=ABO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b6c918580135, createdName=闆锋旦, createdTime=Mon Nov 27 08:27:00 CST 2017, time=2017-11-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=264580, encodeId=5161264580c4, content=温阳助火.都可以增加代谢.从而减肥, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c4a5105539, createdName=lovetcm, createdTime=Sun Nov 26 21:45:56 CST 2017, time=2017-11-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=264245, encodeId=d7cc264245e9, content=学习了.好文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Sat Nov 25 18:59:12 CST 2017, time=2017-11-25, status=1, ipAttribution=)]
    2017-11-26 lovetcm

    温阳助火.都可以增加代谢.从而减肥

    0

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    2017-11-25 1ddf0692m34(暂无匿称)

    学习了.好文章

    0

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