ASN 2015:久坐不动的生活方式可增加肾脏疾病的发病风险

2015-10-21 sunshine 译 MedSci原创

1

据一项新的研究表明,白天长时间的保持坐立不动的姿势可能是慢性肾脏疾病发生的危险因素。该研究结果将于11月3日-8日在美国-圣地亚哥召开的肾脏协会肾脏周(ASN)2015会议上展示。
久坐不动的行为(从事采用坐/卧的姿势的工作,所消耗的热量与休息时所消耗的热量相差不多)通常会与缺乏体力活动(缺乏适度/高强度的体力活动)混淆。久坐不动的行为是糖尿病、高血压以及肥胖的主要危险因素,但是目前尚未清楚久坐不动的行为为何会增加慢性肾病的发病风险。

Dominique Ferranti博士及其同事测量了5873名成年人体力活动的强度以及时间。

结果发现,每天增加80分钟(假定每天清醒16小时)的久坐时间可增加20%慢性肾病的发病风险。此二者之间的关系与适度/高强度体力活动时间,人口统计学因素,冠状动脉疾病,充血性心力衰竭,肺病及机体活动受限情况无关。此外,校正2型糖尿病,高血压以及肥胖情况后,二者仍存在此关联。

“久坐不动的行为,不仅仅是指缺乏适度/高强度的体力活动,可能是慢性肾病发生的一个独立的危险因素,” Dr. Beddhu说道,“有必要去测试久坐不动的行为是否可影响慢性肾病的进展,并因此增加终末肾病的危险。因此,需要实施针对久坐不动行为的干预措施以延缓慢性肾病的进展。”

原始出处:

People with sedentary lifestyles are at increased risk of developing kidney disease. Science Daily, October 20, 2015.

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    2016-01-16 chenhongpeng
  2. [GetPortalCommentsPageByObjectIdResponse(id=1941266, encodeId=8a0319412665d, content=<a href='/topic/show?id=bd2f28e0e1' target=_blank style='color:#2F92EE;'>#ASN#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2870, encryptionId=bd2f28e0e1, topicName=ASN)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1777154, createdName=chenhongpeng, createdTime=Sat Jan 16 23:04:00 CST 2016, time=2016-01-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=45416, encodeId=bc5245416d5, content=sedentarylifestyle, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyhRUzmFEmHvdIaOns4DmF3BicVffXjkOjBTiaMUIA4o7feGvE5IJ0SfSco4ib955Rx7bvWlib7j9V15xp/0, createdBy=814d1631326, createdName=cmn, createdTime=Thu Dec 10 09:00:00 CST 2015, time=2015-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=45417, encodeId=38934541e2a, content=谢谢…, beContent=null, objectType=article, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyhRUzmFEmHvdIaOns4DmF3BicVffXjkOjBTiaMUIA4o7feGvE5IJ0SfSco4ib955Rx7bvWlib7j9V15xp/0, createdBy=814d1631326, createdName=cmn, createdTime=Thu Dec 10 09:00:00 CST 2015, time=2015-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=40603, encodeId=405240603d3, content=我经常长时间坐着,每次喝水都是挺多的,但是小便还是色深, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/03/08/dce92c5acdb74b1ebad9bf7691c2954b.jpg, createdBy=560d1655023, createdName=杨子, createdTime=Sat Oct 24 11:19:00 CST 2015, time=2015-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1630010, encodeId=6d0d16300108c, content=<a href='/topic/show?id=5767233153e' target=_blank style='color:#2F92EE;'>#久坐不动#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23315, encryptionId=5767233153e, topicName=久坐不动)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f62821418601, createdName=lifangping, createdTime=Fri Oct 23 14:04:00 CST 2015, time=2015-10-23, status=1, ipAttribution=)]
    2015-12-10 cmn

    sedentarylifestyle

    0

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    2015-12-10 cmn

    谢谢…

    0

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    2015-10-24 杨子

    我经常长时间坐着,每次喝水都是挺多的,但是小便还是色深

    0

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研究者报告说,青少年肥胖或体重超标会增加未来患终末期肾脏疾病(ESRD)的风险。他们的研究表明青少年过高的体重指数(BMI)与形成糖尿病型和非糖尿病型ESRD有关。 在1967年到1997年间,有1,194,704名以色列青少年,平均年龄为17.4岁,服兵役时做了健康检查。研究者将检查结果和记录了1980年到2010年间接受ESRD治疗的患者信息的登记表结合起来,得出了这种联系。 如Archi