JAMA Psychiatry:催产素可助改善自闭症症状

2014-01-06 蓝建中 新华社

日本研究人员12月19日宣布,他们通过临床试验发现,将女性体内含量较高的一种激素喷射到自闭症患者鼻腔内之后,能够提高其交际能力。自闭症目前尚无治愈疗法,这一新发现或将有助于开发出治疗自闭症的药物。 这种激素就是女性体内分泌较多的催产素。东京大学研究人员在新一期《美国医学会杂志-精神病学》月刊上介绍说,他们用喷雾器向40名成年男性自闭症患者鼻腔喷射催产素,然后让这些患者观看录像。录像上的演员或者用

日本研究人员12月19日宣布,他们通过临床试验发现,将女性体内含量较高的一种激素喷射到自闭症患者鼻腔内之后,能够提高其交际能力。自闭症目前尚无治愈疗法,这一新发现或将有助于开发出治疗自闭症的药物。【原文下载

这种激素就是女性体内分泌较多的催产素。东京大学研究人员在新一期《美国医学会杂志-精神病学》月刊上介绍说,他们用喷雾器向40名成年男性自闭症患者鼻腔喷射催产素,然后让这些患者观看录像。录像上的演员或者用笑脸说厌恶的词汇,或者用厌恶的表情说善意的词汇,总之表情和词汇表达的感情正好相反。

结果发现,自闭症患者鼻腔被喷射催产素后,通过表情判断对方友好度的次数与对照组相比增加了约6%,说明其交际能力得到改善。自闭症患者与普通人相比,往往更加重视对方表达的语言内容,而不太关注对方的表情内涵,因此难以读懂说话对象的真实想法。而喷射催产素之后,自闭症患者理解其他人感情和想法时,发挥作用的对应脑部区域变得活跃起来,喷雾后的效果能够持续数小时。研究小组下一步将继续调查连日喷射是否也有效果。

催产素由脑垂体后叶分泌。通常,人们认为催产素的作用就是为孕妇催产和刺激乳房泌乳。但近年来的一些研究发现,催产素实际上还有一种男女通用的重要作用,对于刺激性欲、让男女之间产生依恋等行为都有重要影响,因此又被称为“爱情激素”。

原文出处

Watanabe T, Abe O, Kuwabara H, Yahata N, Takano Y, Iwashiro N, Natsubori T, Aoki Y, Takao H, Kawakubo Y, Kamio Y, Kato N, Miyashita Y, Kasai K, Yamasue H.Mitigation of Sociocommunicational Deficits of Autism Through Oxytocin-Induced Recovery of Medial Prefrontal Activity: A Randomized Trial.JAMA Psychiatry. 2013 Dec 18【原文下载

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  2. [GetPortalCommentsPageByObjectIdResponse(id=1791861, encodeId=05be1e9186177, content=<a href='/topic/show?id=696a14818df' target=_blank style='color:#2F92EE;'>#Psychiatry#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14818, encryptionId=696a14818df, topicName=Psychiatry)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c192448, createdName=diushouji, createdTime=Thu Nov 20 07:40:00 CST 2014, time=2014-11-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1527548, encodeId=dbed152e548c6, content=<a href='/topic/show?id=68b5863e5d2' target=_blank style='color:#2F92EE;'>#自闭#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86375, encryptionId=68b5863e5d2, topicName=自闭)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=159511872623, createdName=xiongke014, createdTime=Wed Jan 08 05:40:00 CST 2014, time=2014-01-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1529911, encodeId=6fb4152991102, content=<a href='/topic/show?id=010228026b8' target=_blank style='color:#2F92EE;'>#催产#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28026, encryptionId=010228026b8, topicName=催产)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9f1711981795, createdName=zhanfl, createdTime=Wed Jan 08 05:40:00 CST 2014, time=2014-01-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=6585, encodeId=62b7658502, content=催产素号称是爱情激素呢,当然有这个作用。说不定还能改善抑郁症,谁来研究试试?, beContent=null, objectType=article, channel=null, level=null, likeNumber=131, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=lovetcm, createdTime=Mon Jan 06 22:13:00 CST 2014, time=2014-01-06, status=1, ipAttribution=)]
    2014-01-08 xiongke014
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    2014-01-08 zhanfl
  4. [GetPortalCommentsPageByObjectIdResponse(id=1791861, encodeId=05be1e9186177, content=<a href='/topic/show?id=696a14818df' target=_blank style='color:#2F92EE;'>#Psychiatry#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14818, encryptionId=696a14818df, topicName=Psychiatry)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c192448, createdName=diushouji, createdTime=Thu Nov 20 07:40:00 CST 2014, time=2014-11-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1527548, encodeId=dbed152e548c6, content=<a href='/topic/show?id=68b5863e5d2' target=_blank style='color:#2F92EE;'>#自闭#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86375, encryptionId=68b5863e5d2, topicName=自闭)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=159511872623, createdName=xiongke014, createdTime=Wed Jan 08 05:40:00 CST 2014, time=2014-01-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1529911, encodeId=6fb4152991102, content=<a href='/topic/show?id=010228026b8' target=_blank style='color:#2F92EE;'>#催产#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28026, encryptionId=010228026b8, topicName=催产)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9f1711981795, createdName=zhanfl, createdTime=Wed Jan 08 05:40:00 CST 2014, time=2014-01-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=6585, encodeId=62b7658502, content=催产素号称是爱情激素呢,当然有这个作用。说不定还能改善抑郁症,谁来研究试试?, beContent=null, objectType=article, channel=null, level=null, likeNumber=131, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=lovetcm, createdTime=Mon Jan 06 22:13:00 CST 2014, time=2014-01-06, status=1, ipAttribution=)]
    2014-01-06 lovetcm

    催产素号称是爱情激素呢,当然有这个作用。说不定还能改善抑郁症,谁来研究试试?

    0

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