Front Microbiol:耐力运动训练有益肠道菌群平衡

2018-10-19 小通 生物通

《Frontiers in Microbiology》报道,耐力运动训练可以将肠道微生物菌群组成向有益方向改变,经过6周训练,潜在引起炎症的微生物(变形菌)减少,增强新陈代谢的微生物(阿克曼菌)增加。

《Frontiers in Microbiology》报道,耐力运动训练可以将肠道微生物菌群组成向有益方向改变,经过6周训练,潜在引起炎症的微生物(变形菌)减少,增强新陈代谢的微生物(阿克曼菌)增加。

尽管实验者体重没有明显下降,但运动仍具有其他有益影响,芬兰科学院研究员、Jyväskylä大学教员Satu Pekkala说。

“我们发现,VLDL颗粒中的磷脂和胆固醇随运动而降低,这有益于心脏代谢健康,因为VLDL负责将肝脏中的脂质运输到外周组织,循环过程中转化为坏LDL胆固醇,从而危害血管健康。”

运动训练还降低了血管粘附蛋白-1(Vascular adhesion protein-1)活性,具有有益的抗炎作用,特别是对血管系统,虽然本研究未深入调查其潜在机制。

广为人知的阿克曼菌(Akkermansia)是否介导了运动的有益效应,尚需进一步研究。



其他研究表明,体力活动旺盛的志愿者体内的阿克曼属微生物比不活跃的志愿者多得多。这种细菌也是近年来的研究热点,一些科研人员认为它可以预防肥胖和糖尿病

“我们需要更多证据证明阿克曼菌参与调节锻炼导致的一些健康益处,”Pekkala说。

除了肠道微生物组成变化,研究人员还调查了参与运动训练的志愿者的基因和其功能变化。“功能基因表达丰度变化不大,这是可以预料的,因为训练期间饮食没有变化,”Pekkala指出。“如果训练时间增长,也许可能会看到更大效果。”



在这项测试中,研究人员对17名超重女性(之前久坐)进行了为期6周的体能训练(每周三次),训练强度根据心率控制。在测试期间,志愿者的其他生活方式,包括饮食没有改变,以确保运动效果。

原始出处:Munukka Eveliina, Ahtiainen Juha, Puigbo Pere, et al. Six-week endurance exercise alters gut metagenome that is not reflected in systemic metabolism in over-weight women. Front Microbiol, 03 October 2018 

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    2023-02-17 showtest 来自上海

    #耐力运动训练#可以将#肠道微生物#菌群组成向有益方向改变,经过6周训练,潜在引起#炎症#的微生物(变形菌)减少,增强新陈代谢的微生物(#阿克曼菌#)增加。#AKK菌#,这个菌很珍贵,能抗衰老。#长跑##运动锻炼#

    0

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createdTime=Fri Sep 27 18:24:00 CST 2019, time=2019-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1857711, encodeId=5cec185e7116d, content=<a href='/topic/show?id=3f48525849' target=_blank style='color:#2F92EE;'>#CRO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5258, encryptionId=3f48525849, topicName=CRO)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c30265, createdName=jiafufeng@yaho, createdTime=Wed Jan 02 03:24:00 CST 2019, time=2019-01-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1918344, encodeId=4ed5191834446, content=<a href='/topic/show?id=4f26341994' target=_blank style='color:#2F92EE;'>#Bio#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3419, encryptionId=4f26341994, topicName=Bio)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Fri Apr 26 03:24:00 CST 2019, time=2019-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1971326, encodeId=7ef419e1326bc, content=<a href='/topic/show?id=ef2680345df' target=_blank style='color:#2F92EE;'>#耐力运动#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80345, encryptionId=ef2680345df, topicName=耐力运动)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a691420, createdName=30397604, createdTime=Fri Sep 20 14:24:00 CST 2019, time=2019-09-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1954921, encodeId=c691195492169, content=<a href='/topic/show?id=d5079422460' target=_blank style='color:#2F92EE;'>#运动训练#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94224, encryptionId=d5079422460, topicName=运动训练)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Mon Sep 16 01:24:00 CST 2019, time=2019-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2084452, encodeId=adb220844520b, content=<a href='/topic/show?id=61f411e013b' target=_blank style='color:#2F92EE;'>#Micro#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11701, encryptionId=61f411e013b, topicName=Micro)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d59291, createdName=xjy02, createdTime=Fri May 24 16:24:00 CST 2019, time=2019-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=360269, encodeId=2ee23602697a, content=学习了,非常实用的操作技术,值得借鉴的临床经验和学习资料,涨知识,获益匪浅,感谢分享!, beContent=null, objectType=article, 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content=<a href='/topic/show?id=507881e38b7' target=_blank style='color:#2F92EE;'>#肠道菌群平衡#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81738, encryptionId=507881e38b7, topicName=肠道菌群平衡)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f5b299, createdName=xuyu, createdTime=Thu Apr 04 11:24:00 CST 2019, time=2019-04-04, status=1, ipAttribution=)]
  4. 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createdTime=Fri Sep 27 18:24:00 CST 2019, time=2019-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1857711, encodeId=5cec185e7116d, content=<a href='/topic/show?id=3f48525849' target=_blank style='color:#2F92EE;'>#CRO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5258, encryptionId=3f48525849, topicName=CRO)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c30265, createdName=jiafufeng@yaho, createdTime=Wed Jan 02 03:24:00 CST 2019, time=2019-01-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1918344, encodeId=4ed5191834446, content=<a href='/topic/show?id=4f26341994' target=_blank style='color:#2F92EE;'>#Bio#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3419, encryptionId=4f26341994, topicName=Bio)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Fri Apr 26 03:24:00 CST 2019, time=2019-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1971326, encodeId=7ef419e1326bc, content=<a href='/topic/show?id=ef2680345df' target=_blank style='color:#2F92EE;'>#耐力运动#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80345, encryptionId=ef2680345df, topicName=耐力运动)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a691420, createdName=30397604, createdTime=Fri Sep 20 14:24:00 CST 2019, time=2019-09-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1954921, encodeId=c691195492169, content=<a href='/topic/show?id=d5079422460' target=_blank style='color:#2F92EE;'>#运动训练#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94224, encryptionId=d5079422460, topicName=运动训练)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Mon Sep 16 01:24:00 CST 2019, time=2019-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2084452, encodeId=adb220844520b, content=<a href='/topic/show?id=61f411e013b' target=_blank style='color:#2F92EE;'>#Micro#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11701, encryptionId=61f411e013b, topicName=Micro)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d59291, createdName=xjy02, createdTime=Fri May 24 16:24:00 CST 2019, time=2019-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=360269, encodeId=2ee23602697a, content=学习了,非常实用的操作技术,值得借鉴的临床经验和学习资料,涨知识,获益匪浅,感谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/02/27/c53a212859edcad4f60a54feffff50bb.jpg, createdBy=67cf1525321, createdName=13718711b3m, createdTime=Sat Feb 09 17:19:23 CST 2019, time=2019-02-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=358049, encodeId=88fc35804969, content=很不错的学习资料,值得借鉴与分享的临床经验,学习了,获益匪浅,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/02/27/c53a212859edcad4f60a54feffff50bb.jpg, createdBy=67cf1525321, createdName=13718711b3m, createdTime=Sun Jan 13 17:49:32 CST 2019, time=2019-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1808446, encodeId=5509180844610, content=<a href='/topic/show?id=507881e38b7' target=_blank style='color:#2F92EE;'>#肠道菌群平衡#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81738, encryptionId=507881e38b7, topicName=肠道菌群平衡)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f5b299, createdName=xuyu, createdTime=Thu Apr 04 11:24:00 CST 2019, time=2019-04-04, status=1, ipAttribution=)]
    2019-04-26 sunylz
  5. 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  6. 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topicName=null, topicId=null, topicList=[TopicDto(id=94224, encryptionId=d5079422460, topicName=运动训练)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Mon Sep 16 01:24:00 CST 2019, time=2019-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2084452, encodeId=adb220844520b, content=<a href='/topic/show?id=61f411e013b' target=_blank style='color:#2F92EE;'>#Micro#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11701, encryptionId=61f411e013b, topicName=Micro)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d59291, createdName=xjy02, createdTime=Fri May 24 16:24:00 CST 2019, time=2019-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=360269, encodeId=2ee23602697a, content=学习了,非常实用的操作技术,值得借鉴的临床经验和学习资料,涨知识,获益匪浅,感谢分享!, beContent=null, objectType=article, 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  7. 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topicName=null, topicId=null, topicList=[TopicDto(id=94224, encryptionId=d5079422460, topicName=运动训练)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Mon Sep 16 01:24:00 CST 2019, time=2019-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2084452, encodeId=adb220844520b, content=<a href='/topic/show?id=61f411e013b' target=_blank style='color:#2F92EE;'>#Micro#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11701, encryptionId=61f411e013b, topicName=Micro)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d59291, createdName=xjy02, createdTime=Fri May 24 16:24:00 CST 2019, time=2019-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=360269, encodeId=2ee23602697a, content=学习了,非常实用的操作技术,值得借鉴的临床经验和学习资料,涨知识,获益匪浅,感谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/02/27/c53a212859edcad4f60a54feffff50bb.jpg, createdBy=67cf1525321, createdName=13718711b3m, createdTime=Sat Feb 09 17:19:23 CST 2019, time=2019-02-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=358049, encodeId=88fc35804969, content=很不错的学习资料,值得借鉴与分享的临床经验,学习了,获益匪浅,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/02/27/c53a212859edcad4f60a54feffff50bb.jpg, createdBy=67cf1525321, createdName=13718711b3m, createdTime=Sun Jan 13 17:49:32 CST 2019, time=2019-01-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1808446, encodeId=5509180844610, content=<a href='/topic/show?id=507881e38b7' target=_blank style='color:#2F92EE;'>#肠道菌群平衡#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81738, encryptionId=507881e38b7, topicName=肠道菌群平衡)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f5b299, createdName=xuyu, createdTime=Thu Apr 04 11:24:00 CST 2019, time=2019-04-04, status=1, ipAttribution=)]
    2019-05-24 xjy02
  8. 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content=<a href='/topic/show?id=507881e38b7' target=_blank style='color:#2F92EE;'>#肠道菌群平衡#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81738, encryptionId=507881e38b7, topicName=肠道菌群平衡)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f5b299, createdName=xuyu, createdTime=Thu Apr 04 11:24:00 CST 2019, time=2019-04-04, status=1, ipAttribution=)]
    2019-02-09 13718711b3m

    学习了,非常实用的操作技术,值得借鉴的临床经验和学习资料,涨知识,获益匪浅,感谢分享!

    0

  9. 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    2019-01-13 13718711b3m

    很不错的学习资料,值得借鉴与分享的临床经验,学习了,获益匪浅,谢谢分享!

    0

  10. 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