Eur Heart J：冠脉疾病患者筛查糖尿病 **OGTT

2015-02-15 高晓方医学论坛网

瑞典一项研究表明，在伴有确定性冠脉疾病的患者中，口服糖耐量试验(OGTT)确认的既往未诊断糖尿病患者比率最高，并应作为评估类此患者血糖状况的首选检测。论文2月9日在线发表于《欧洲心脏杂志》(Eur Heart J)。 此项研究共纳入4004例既往无糖尿病病史的冠脉疾病患者，并测定空腹血糖(FPG)、2小时餐后血糖(2hPG)和糖化血红蛋白A1c(HbA1c)。依据ADA和WHO血糖异常标

瑞典一项研究表明，在伴有确定性冠脉疾病的患者中，口服糖耐量试验(OGTT)确认的既往未诊断糖尿病患者比率最高，并应作为评估类此患者血糖状况的首选检测。论文2月9日在线发表于《欧洲心脏杂志》(Eur Heart J)。

此项研究共纳入4004例既往无糖尿病病史的冠脉疾病患者，并测定空腹血糖(FPG)、2小时餐后血糖(2hPG)和糖化血红蛋白A1c(HbA1c)。依据ADA和WHO血糖异常标准将受试者分为三个不同的血糖分类。评估FPG、HbA1c和2hPG单独或联合确认血糖异常的效能和一致性。结果显示，1158例(29%)患者伴有未检出糖尿病，其中由FPG、2hPG、HbA1c确认的比率分别为75%、40%和17%，由FPG+HbA1c和OGTT(=FPG+2hPG)确认的比率分别为81%和96%。

仅有7%的患者由FPG、HbA1c和2hPG三种方法均加以确认。 ADA标准(FPG+HbA1c)和WHO标准(OGTT=FPG+2hPG)分别确认90%和73%的患者。依据ADA标准筛查可将66%的患者确定为糖尿病高危，依据WHO标准则为46%。

原始出处：

Gyberg V, De Bacquer D, Kotseva K, De Backer G, Schnell O, Sundvall J, Tuomilehto J, Wood D, Rydén L; on behalf of EUROASPIRE IV Investigators.Screening for dysglycaemia in patients with coronary artery disease as reflected by fasting glucose, oral glucose tolerance test, and HbA1c: a report from EUROASPIRE IV-a survey from the European Society of Cardiology.Eur Heart J. 2015 Feb 9. pii: ehv008. [Epub ahead of print]

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2015-02-28 hmwwww

#疾病患者#

36 0
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2015-02-28 慧读

有用

179 0
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2015-02-19 午夜星河

看执行力度

99 0
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2015-02-17 shenxlcyp

#OGTT#

36 0
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2015-02-17 zhaojie88

#ART#

27 0
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2015-02-17 爆笑小医

#HEART#

0 0
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2015-02-17 huangshifeng

#冠脉疾病#

41 0
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2015-02-16 Johnny1989

已阅

106 0
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2015-02-16 windmilL1989

赞

98 0
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2015-02-15 223.104.5.**

过于敏感会不会过度诊断?

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