ENDO 2018:无糖、低热量?人造甜味剂危害健康有新证:从细胞水平升高血糖血脂

2018-03-28 卢芳 中国循环杂志

糖,如今被广为诟病,但打着无糖、低热量甚至无热量招牌的人造甜味剂就安全无忧吗?

糖,如今被广为诟病,但打着无糖、低热量甚至无热量招牌的人造甜味剂就安全无忧吗?

近日一项来自美国乔治华盛顿大学的研究表明,人造甜味剂也不是什么“好鸟”。

研究显示,在各种食物中广为存在的人造甜味剂三氯蔗糖,在细胞水平即开始“作祟”。一旦进肚,会促进人体葡萄糖摄取,促进炎症水平和脂肪形成。而且这种作用在肥胖人群中更为显著。

这项研究共纳入18位体重正常和肥胖受试者,其中多数人为糖尿病前期患者。

结果发现,三氯蔗糖与脂肪形成相关基因的上调呈剂量依赖关系。而且所有受试者甘油三酯均明显增高。

糖脂代谢异常在肥胖受试者中体现更为显著。

研究者指出,都说糖不好,但是人造甜味剂就能代替糖?可能带来的危害比糖还大。肥胖的人而言,还是暂别甜食和加了人造甜味剂的饮料吧。

当前货架上很多的食物饮料,里面添加的不仅仅是三氯蔗糖,还有其他的人造甜味剂,或者是几种混杂在一起,研究者表示他们正进行的一项前瞻性研究,对其他人造甜味剂也要深入“调查”一番。

这项研究也为之前发表的多项研究加了脚注。

比如一项加拿大学者进行的研究就显示,一些为期较长的观察性研究发现食用人工甜味剂与体重增加、肥胖、高血压糖尿病、心脏病等相关。

还有研究显示,人造甜味剂还与降低试管婴儿移植与怀孕的成功率相关,推测可能导致卵子以及由这些卵子受精后形成的胚胎质量变差。

另外,孕期如果母亲人造甜味剂摄入的多,还会增加后代为大于胎龄儿和7岁时超重/肥胖风险。

一言以蔽之,糖少吃,加了人造甜味剂的各种食物也应适可而止。

原始出处:
Nabanita Kundu, et al. SUN-071 - Sucralose Promotes Metabolic Dysregulation and Intracellular ROS Accumulation. The Endocrine Society's Annual Meeting-Abstract. Mar 18, 2018.

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    2018-05-20 1771ae4158m

    学习一下很不错

    0

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    2018-04-01 jihuaijun1112

    学习学习学习

    0

  4. 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07:16:26 CST 2018, time=2018-03-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=300818, encodeId=9081300818e7, content=了解了解.继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Thu Mar 29 08:17:13 CST 2018, time=2018-03-29, status=1, ipAttribution=)]
    2018-04-01 jihuaijun1112

    学习学习学习

    0

  5. 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07:16:26 CST 2018, time=2018-03-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=300818, encodeId=9081300818e7, content=了解了解.继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Thu Mar 29 08:17:13 CST 2018, time=2018-03-29, status=1, ipAttribution=)]
    2018-03-30 changjiu

    谢谢学习一下

    0

  6. 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07:16:26 CST 2018, time=2018-03-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=300818, encodeId=9081300818e7, content=了解了解.继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Thu Mar 29 08:17:13 CST 2018, time=2018-03-29, status=1, ipAttribution=)]
    2018-03-30 hbwxf
  7. 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07:16:26 CST 2018, time=2018-03-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=300818, encodeId=9081300818e7, content=了解了解.继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Thu Mar 29 08:17:13 CST 2018, time=2018-03-29, status=1, ipAttribution=)]
  8. 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  9. 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07:16:26 CST 2018, time=2018-03-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=300818, encodeId=9081300818e7, content=了解了解.继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Thu Mar 29 08:17:13 CST 2018, time=2018-03-29, status=1, ipAttribution=)]
    2018-03-30 jihuaijun1112

    学习学习学习.

    0

  10. 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    2018-03-29 1dd8c52fm63(暂无匿称)

    了解了解.继续关注

    0

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应该用人造甜味剂代替糖吗?

我们知道澳大利亚人对糖的消费量很大。澳大利亚统计局的最新结果显示,52%的人口比建议的消费多,这影响到体重和牙齿健康。对糖的批评如此普遍,以至于牛奶和水果等食物中的糖也遭到了攻击。我们应该注意,我们需要关注的是添加糖。像水果和牛奶这样的天然食品还有许多其他有益成分。与其他糖类物质相比,比如软饮料,水果中还含有维生素、纤维和各种植物化学物质。我们从全食超市消费的糖量通常较低,因为每份的糖量都较低。至