AZ收购了Ionis的NASH候选药物

2018-04-10 MedSci MedSci原创

阿斯利康已经购买了Ionis Pharmaceuticals的实验性反义疗法,交易价值可能超过3亿美元。Ionis说,这一举措是建立在公司之间现有的战略合作伙伴关系基础之上,由于药物进入开发阶段引起的。IONIS-AZ6-2.5-LRx / AZD2693旨在抑制一种未公开的靶点治疗非酒精性脂肪性肝炎(NASH)患者,这是一种非酒精性脂肪性肝病的进行性形式。AZ将向Ionis支付3000万美元的许


阿斯利康已经购买了Ionis Pharmaceuticals的实验性反义疗法,交易价值可能超过3亿美元。

Ionis说,这一举措是建立在公司之间现有的战略合作伙伴关系基础之上,由于药物进入开发阶段引起的。

IONIS-AZ6-2.5-LRx / AZD2693旨在抑制一种未公开的靶点治疗非酒精性脂肪性肝炎(NASH)患者,这是一种非酒精性脂肪性肝病的进行性形式。

AZ将向Ionis支付3000万美元的许可费,并承担进一步开发和药物商业化的责任。

Ionis还可以获得高达3亿美元的额外开发和监管里程碑费用,以及如果将药物推向市场,则可以从药物的销售中扣除特许权使用费等级。

Ionis制药公司反义药物发现和转化医学高级副总裁Brett Monia指出:"这是我们与阿斯利康的战略合作开发的第三种药物,用于发现治疗心血管,肾脏和代谢疾病的药物。"

"通过在NASH提供临床前和开发方面的专业知识,阿斯利康在推进此项计划方面发挥了战略性作用,为药物的快速发展做出了贡献。我们期待阿斯利康将此计划迅速推向临床试验阶段,并最终推向市场。"


此文系梅斯医学(MedSci)原创整理编译,转载需授权!

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1714777, encodeId=cc6a1e14777aa, content=<a href='/topic/show?id=021230e312' target=_blank style='color:#2F92EE;'>#AZ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3073, encryptionId=021230e312, topicName=AZ)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9e5031899089, createdName=12498e5fm22(暂无昵称), createdTime=Sun Feb 03 01:49:00 CST 2019, time=2019-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2052404, encodeId=2e8720524044f, content=<a href='/topic/show?id=688a2e469f0' target=_blank style='color:#2F92EE;'>#候选药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=27469, encryptionId=688a2e469f0, topicName=候选药物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=467c360, createdName=yuanming7, createdTime=Sat Jan 05 21:49:00 CST 2019, time=2019-01-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1301238, encodeId=7dbe13012389d, content=<a href='/topic/show?id=38e32852fe' target=_blank style='color:#2F92EE;'>#ASH#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2852, encryptionId=38e32852fe, topicName=ASH)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=39a0295, createdName=kksonne, createdTime=Thu Apr 12 12:49:00 CST 2018, time=2018-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1509640, encodeId=cf9f1509640f6, content=<a href='/topic/show?id=a9e09969c4' target=_blank style='color:#2F92EE;'>#Ionis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9969, encryptionId=a9e09969c4, topicName=Ionis)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0a7810117141, createdName=AspirantSuo, createdTime=Thu Apr 12 12:49:00 CST 2018, time=2018-04-12, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1714777, encodeId=cc6a1e14777aa, content=<a href='/topic/show?id=021230e312' target=_blank style='color:#2F92EE;'>#AZ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3073, encryptionId=021230e312, topicName=AZ)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9e5031899089, createdName=12498e5fm22(暂无昵称), createdTime=Sun Feb 03 01:49:00 CST 2019, time=2019-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2052404, encodeId=2e8720524044f, content=<a href='/topic/show?id=688a2e469f0' target=_blank style='color:#2F92EE;'>#候选药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=27469, encryptionId=688a2e469f0, topicName=候选药物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=467c360, createdName=yuanming7, createdTime=Sat Jan 05 21:49:00 CST 2019, time=2019-01-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1301238, encodeId=7dbe13012389d, content=<a href='/topic/show?id=38e32852fe' target=_blank style='color:#2F92EE;'>#ASH#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2852, encryptionId=38e32852fe, topicName=ASH)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=39a0295, createdName=kksonne, createdTime=Thu Apr 12 12:49:00 CST 2018, time=2018-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1509640, encodeId=cf9f1509640f6, content=<a href='/topic/show?id=a9e09969c4' target=_blank style='color:#2F92EE;'>#Ionis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9969, encryptionId=a9e09969c4, topicName=Ionis)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0a7810117141, createdName=AspirantSuo, createdTime=Thu Apr 12 12:49:00 CST 2018, time=2018-04-12, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1714777, encodeId=cc6a1e14777aa, content=<a href='/topic/show?id=021230e312' target=_blank style='color:#2F92EE;'>#AZ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3073, encryptionId=021230e312, topicName=AZ)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9e5031899089, createdName=12498e5fm22(暂无昵称), createdTime=Sun Feb 03 01:49:00 CST 2019, time=2019-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2052404, encodeId=2e8720524044f, content=<a href='/topic/show?id=688a2e469f0' target=_blank style='color:#2F92EE;'>#候选药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=27469, encryptionId=688a2e469f0, topicName=候选药物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=467c360, createdName=yuanming7, createdTime=Sat Jan 05 21:49:00 CST 2019, time=2019-01-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1301238, encodeId=7dbe13012389d, content=<a href='/topic/show?id=38e32852fe' target=_blank style='color:#2F92EE;'>#ASH#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2852, encryptionId=38e32852fe, topicName=ASH)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=39a0295, createdName=kksonne, createdTime=Thu Apr 12 12:49:00 CST 2018, time=2018-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1509640, encodeId=cf9f1509640f6, content=<a href='/topic/show?id=a9e09969c4' target=_blank style='color:#2F92EE;'>#Ionis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9969, encryptionId=a9e09969c4, topicName=Ionis)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0a7810117141, createdName=AspirantSuo, createdTime=Thu Apr 12 12:49:00 CST 2018, time=2018-04-12, status=1, ipAttribution=)]
    2018-04-12 kksonne
  4. [GetPortalCommentsPageByObjectIdResponse(id=1714777, encodeId=cc6a1e14777aa, content=<a href='/topic/show?id=021230e312' target=_blank style='color:#2F92EE;'>#AZ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3073, encryptionId=021230e312, topicName=AZ)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9e5031899089, createdName=12498e5fm22(暂无昵称), createdTime=Sun Feb 03 01:49:00 CST 2019, time=2019-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2052404, encodeId=2e8720524044f, content=<a href='/topic/show?id=688a2e469f0' target=_blank style='color:#2F92EE;'>#候选药物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=27469, encryptionId=688a2e469f0, topicName=候选药物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=467c360, createdName=yuanming7, createdTime=Sat Jan 05 21:49:00 CST 2019, time=2019-01-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1301238, encodeId=7dbe13012389d, content=<a href='/topic/show?id=38e32852fe' target=_blank style='color:#2F92EE;'>#ASH#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2852, encryptionId=38e32852fe, topicName=ASH)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=39a0295, createdName=kksonne, createdTime=Thu Apr 12 12:49:00 CST 2018, time=2018-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1509640, encodeId=cf9f1509640f6, content=<a href='/topic/show?id=a9e09969c4' target=_blank style='color:#2F92EE;'>#Ionis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9969, encryptionId=a9e09969c4, topicName=Ionis)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0a7810117141, createdName=AspirantSuo, createdTime=Thu Apr 12 12:49:00 CST 2018, time=2018-04-12, status=1, ipAttribution=)]
    2018-04-12 AspirantSuo

相关资讯

AZ的Forxiga将用于I型糖尿病患者

欧洲药品管理局已经接受阿斯利康公司(AZ)提交Forxiga作为I型糖尿病治疗药物的申请。该事件包含来自III期DEPICT临床计划的数据,该数据显示,与安慰剂相比,Forxiga作为I型糖尿病控制不佳的患者的可调胰岛素口服辅助药物,在24周和52周时可显着降低HbA1c,体重和每日胰岛素总量。在安全性方面,除了更多数量的糖尿病酮症酸中毒(DKA)事件(已知在I型糖尿病患者中发生频率更高)之外,该