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Diabetologia：后负荷血浆葡萄糖浓度可作为西南印第安人2型糖尿病的预测因子

2017-09-30 MedSci MedSci原创

2型糖尿病
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近日，国际杂志 《Diabetologia》上在线发表一项关于1小时和2小时后后负荷血浆葡萄糖浓度可作为西南印第安人2型糖尿病的预测因子的研究。

近日，国际杂志 《Diabetologia》上在线发表一项关于1小时和2小时后后负荷血浆葡萄糖浓度可作为西南印第安人2型糖尿病的预测因子的研究。 在75g OGTT期间升高的2小时血浆葡萄糖浓度（2h-PG）预测2型糖尿病的发展。然而，1-h血浆葡萄糖浓度（1h-PG）与胰岛素分泌相关，可能作为更好的2型糖尿病预测因子。在本项研究中，研究人员旨在调查1 h-PG和2 h-PG之间的联系，使用金标准方法测量胰岛素分泌和作用。同时，研究人员还对1 h-PG和2 h-PG作为2型糖尿病的预测因子进行了比较。 这项分析包括无糖尿病的成年志愿者，主要是西南的美洲原住民的后裔，他们参与了1965年至2007年的纵向流行病学研究，包括基线OGTT测量1h-PG。第1组（n=716）分别进行了IVGTT和高胰岛素-正葡萄糖钳夹试验，用于测量急性胰岛素反应（AIR）和胰岛素刺激的葡萄糖反应（M）。 并对第1组中的一些成员（N=490共716）和第二组成员（数量较大N= 1946）随访评估2型糖尿病的发展（随访中位数分别为9.0和12.8年）。 与2h-PG（r= -0.281）相比，1 h-PG（r=

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    2018-08-19 一一一多

    学习了

    0

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    2017-11-24 ms5439512287675881

    #BET#

    0

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    2018-03-31 ms9608593228839890

    #DIA#

    0

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    2017-10-02 宋威

    #预测因子#

    0

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    2017-10-02 12498974m55暂无昵称

    #浓度#

    0

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