系统评价和荟萃分析方案:中医健脾疗法治疗运动性疲劳

2022-03-07 August MedSci原创

运动性疲劳(EIF)是体育比赛和训练中常见的现象。可能会给运动员的运动技能执行和认知带来麻烦。

运动诱发的疲劳 (EIF) 是由于剧烈和长时间的运动而导致的最大随意肌力的降低,这成为体育比赛和体能训练中普遍存在的现象。EIF 在疾病中的潜在机制似乎与神经炎症通路密切相关。研究表明,疲劳运动后对运动员眼球运动的控制受损。长期使用骨骼运动系统对动眼神经系统的功能有不利影响,表明中枢疲劳的潜在作用。在没有充分恢复的情况下长时间剧烈运动导致的 EIF 不仅会影响运动技能的执行,还会损害突触可塑性和认知功能,例如注意力广度、信息处理和决策。虽然中药健脾疗法已被普遍用于EIF管理,但关于健脾疗法有效性和安全性的相关证据仍不清楚。

方法:检索PubMed、Embase、Web of Science、Cochrane图书馆、SinoMed、中国科技期刊数据库(VIP)、中国知网(CNKI)、万方等数据库,从数据库中检索2000年至2021年的相关随机对照试验. 纳入中药健脾疗法治疗EIF的随机对照试验。系统审查和数据的荟萃分析将根据系统审查和荟萃分析 (PRISMA)指南的首选报告项目在 RevMan 5.3 中进行。两位作者独立进行文献检索、数据提取和质量评价。使用 Cochrane 随机临床试验偏倚风险工具评估偏倚风险。结果:本系统回顾和荟萃分析将总结中医健脾疗法在 EIF 中的最新证据。结果将在完成后提交给同行评审的期刊。

随着世界各国体育教育的不断发展,人们对竞技体育的期望也越来越高。为提高运动员的控制能力和竞技水平,运动后需要缓解疲劳。EIF越来越受到社会和国家的重视。中药健脾药材“黄芪”是一种流行的“补气”药材,具有悠久的使用历史,具有多种生物功能,可提高运动表现并改善 EIF,减少运动引起的副产物血液的积累乳酸和氨与急性运动挑战。

人参是一种著名的中药健脾疗法,潜在地通过调节肠道菌群来改善 EIF,从机制上讲,人参中的糖类和人参皂苷在 EIF 的治疗中发挥着重要作用,它们作为特定肠道细菌的能量底物,从而有效地调节在肠道微生物群中最重要的是,人参触发了几个独特且关键的分子和细胞信号通路,以对 EIF 进行有益反应研究表明,红景天通过抑制骨骼肌中的线粒体自噬来缓解力竭性 EIF,其机制可能与通过抑制 PINK1/Parkin 信号通路提高抗氧化活性、增强能量产生和抑制线粒体自噬有关。

综上所述,此研究结论将为支持中药健脾疗法作为 EIF 患者的有效干预措施提供证据。

 

原文:Geng X, Guo X, Liu B, Yu P, Li J, Pan H. Traditional Chinese medicine Jianpi therapy in exercise-induced fatigue: A protocol for systematic review and meta-analysis. Medicine (Baltimore). 2022;101(2):e28594. doi:10.1097/MD.0000000000028594

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    2022-08-22 venlin
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    2022-03-08 ms5000000078691768

    已学习

    0

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    2022-03-07 tamgche
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    2022-03-07 huagfeg
  6. [GetPortalCommentsPageByObjectIdResponse(id=1681462, encodeId=0b18168146288, content=<a href='/topic/show?id=366b8e2299e' target=_blank style='color:#2F92EE;'>#荟萃#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87229, encryptionId=366b8e2299e, topicName=荟萃)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c12d27855367, createdName=venlin, createdTime=Mon Aug 22 19:50:45 CST 2022, time=2022-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1837019, encodeId=d992183e01986, content=<a href='/topic/show?id=1f188e230c5' target=_blank style='color:#2F92EE;'>#荟萃分析#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87230, encryptionId=1f188e230c5, topicName=荟萃分析)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b79433, createdName=fangcong, createdTime=Sun Nov 06 09:50:45 CST 2022, time=2022-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1200483, encodeId=58b71200483ec, content=已学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=07586536952, createdName=ms5000000078691768, createdTime=Tue Mar 08 09:52:01 CST 2022, time=2022-03-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1260952, encodeId=abd5126095216, content=<a href='/topic/show?id=493ee0559a7' target=_blank style='color:#2F92EE;'>#疲劳#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70559, encryptionId=493ee0559a7, topicName=疲劳)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=674961, createdName=tamgche, createdTime=Mon Mar 07 15:50:45 CST 2022, time=2022-03-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1444760, encodeId=0dee1444e6000, content=<a href='/topic/show?id=3d9291459d1' target=_blank style='color:#2F92EE;'>#评价#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91459, encryptionId=3d9291459d1, topicName=评价)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1fee5134542, createdName=huagfeg, createdTime=Mon Mar 07 15:50:45 CST 2022, time=2022-03-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1200209, encodeId=ddc81200209b6, content=好文章,谢谢分享。, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJlfgys76DEiaNtbYo2re3ibjrUPTRibEXRyFwAB4aAGiave842S0FQDf0wAoaH226NiaSoPPDzhndsf1g/132, createdBy=88b489038, createdName=yangchou, createdTime=Mon Mar 07 12:55:11 CST 2022, time=2022-03-07, status=1, ipAttribution=)]
    2022-03-07 yangchou

    好文章,谢谢分享。

    0

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