我国台湾11年随访研究:老年高血压患者用钙拮抗剂可降低骨折风险

2017-01-05 朱朱 中国循环杂志

由于骨质疏松,老年人成为骨折的高发人群,而应用某些降压药物的老年高血压患者发生骨折的风险可能更高。 近期发表在《中华医学杂志》英文版的一项来自我国台湾的队列研究提示,应用钙拮抗剂(CCB)的老年高血压患者骨折风险降低,而应用血管紧张素转换酶抑制剂(ACEI)的患者骨折风险则升高。 研究人员在校正年龄、性别、合并症和同期服用的药物等因素后发现,在11年随访期间,应用CCB的老年高

由于骨质疏松,老年人成为骨折的高发人群,而应用某些降压药物的老年高血压患者发生骨折的风险可能更高。
 
近期发表在《中华医学杂志》英文版的一项来自我国台湾的队列研究提示,应用钙拮抗剂(CCB)的老年高血压患者骨折风险降低,而应用血管紧张素转换酶抑制剂(ACEI)的患者骨折风险则升高。
 
研究人员在校正年龄、性别、合并症和同期服用的药物等因素后发现,在11年随访期间,应用CCB的老年高血压患者新发骨质疏松性骨折的风险比不用CCB者降低30%,而用ACEI的患者比不用ACEI者骨折风险则增加64%。应用袢利尿剂、噻嗪类利尿剂、血管紧张素受体拮抗剂(ARB)、β受体阻滞剂和α受体阻滞剂与新发骨质疏松性骨折无明显关系。
 
这项研究调取了我国台湾台中65~80岁老年患者的医保数据,11年随访期间,1144例高血压患者中,128例新发骨质疏松性骨折。
 
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    2017-01-16 habb
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    2017-01-07 虈亣靌

    内容不错,己拜读。

    0

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由上海瑞金医院王继光等进行的研究显示,高血压和糖尿病共患率较高,但对于心内科和内分泌科而言,前来就诊的二病并存患者,前者控糖药物使用不够,后者降压药物使用不足,血压血糖均达标者两科均不过半。 研究者指出,或许高血压和糖尿病联合管理平台有助于提高和改善当前救治状况。 研究显示,在心内科就诊的高血压患者约有1/3同时罹患糖尿病,而在内分泌科就诊的糖尿病患者中则有约2/3合并高血压。

高血压伴高尿酸血症的研究进展

作者:卢新政 邹花一阳单位:江苏省人民医院(南京医科大学第一附属医院、南京医科大学附属医院)[1] 高血压与高尿酸作为心血管疾病两个危险因素[1],近年在中国逐渐增多。高血压与高尿酸相互影响,两者并存时,心脑血管疾病风险明显增加。因此,高血压合并高尿酸血症的临床诊治与管理很重要。1 流行病学1870年最早发现,血尿酸与高血压的发生发展有关。早期,人们将其归因于肾血管收缩,引