Obstet Gynecol:早产出生的女性怀孕时也容易早产?

2015-05-05 MedSci译 MedSci原创

女性系早产,那么该女性妊娠时早产风险是否会增加,如果风险会增加,那么孕妇早产的并发症如高血压或糖尿病解释能否这种风险。Boivin A 等人在1976-1995年间于加拿大魁北克进行了一项基于人群的队列研究,该人群共有51,148早产女性,823,991名足月产下的女性,按1:2配对,评估早产的妇女和他们的后代之间的关系。这项研究包括7405名女性出生时是早产的女性(554名怀孕32周之前出生和6

女性系早产,那么该女性妊娠时早产风险是否会增加,如果风险会增加,那么孕妇早产的并发症如高血压糖尿病解释能否这种风险。

Boivin A 等人在1976-1995年间于加拿大魁北克进行了一项基于人群的队列研究,该人群共有51,148早产女性,823,991名足月产下的女性,按1:2配对,评估早产的妇女和他们的后代之间的关系。

这项研究包括7405名女性出生时是早产的女性(554名怀孕32周之前出生和6851名32-36周孕出生)和16714名足月妊娠出生的女性,两组人群各自分娩了12248和27879名新生儿。总体来看,14.2% 的32周之前出生的孕妇分娩了至少一次的早产儿,13.0%的32-36周孕出生的孕妇分娩了至少一次的早产儿,而足月出生的孕妇中有9.8%的早产,三组孕妇中极早产儿的数据分别为2.4%, 1.8%,1.2%(both P<.001 for trend)。

校正妊娠并发症等因素后发现,32周之前出生的孕妇分娩早产儿的风险是足月产孕妇的1.63倍(95% CI 1.22-2.19),而32-36周孕出生的孕妇分娩早产儿的风险是足月产孕妇的1.41倍(95% CI 1.27-1.57)。

研究结果表明,早产出生的女性其妊娠时早产风险增加,且是与妊娠并发症如妊娠期高血压妊娠期糖尿病无关的独立危险因素。

原始出处:

Boivin A, Luo ZC, Audibert F, et al. Risk for preterm and very preterm delivery in women who were born preterm. Obstet Gynecol. 2015. 125(5): 1177-84.

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  1. [GetPortalCommentsPageByObjectIdResponse(id=2043850, encodeId=16262043850cd, content=<a href='/topic/show?id=8513126129d' target=_blank style='color:#2F92EE;'>#NEC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12612, encryptionId=8513126129d, topicName=NEC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1ac22500003, createdName=1249842em09(暂无昵称), createdTime=Mon Jun 08 22:57:00 CST 2015, time=2015-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2011188, encodeId=866520111887c, content=<a href='/topic/show?id=840d1e300e5' target=_blank style='color:#2F92EE;'>#TET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17300, encryptionId=840d1e300e5, topicName=TET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cc52251, createdName=yhy100200, createdTime=Sat Aug 15 18:57:00 CST 2015, time=2015-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=22827, encodeId=a6b92282ecc, content=不错哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Wed May 06 22:15:00 CST 2015, time=2015-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=22733, encodeId=3f3f22e3356, content=不错~~, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=chaie1217, createdTime=Wed May 06 12:59:00 CST 2015, time=2015-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=22698, encodeId=b257226989b, content=这个视角很特殊, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=61.171.184.**, createdTime=Tue May 05 23:11:00 CST 2015, time=2015-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=22670, encodeId=83b7226e08b, content=了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3yz0JbjHQ7nicJU7lHMOu0Itf3Zv3VBzEvK3k4AFPBXhiaxIRNGVI33GicoRXQEjkaasjdlWKwZuwcyhDP9Jibqt5ct/0, createdBy=f1281613275, createdName=zhouanxiu, createdTime=Tue May 05 22:49:00 CST 2015, time=2015-05-05, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=2043850, encodeId=16262043850cd, content=<a href='/topic/show?id=8513126129d' target=_blank style='color:#2F92EE;'>#NEC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12612, encryptionId=8513126129d, topicName=NEC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1ac22500003, createdName=1249842em09(暂无昵称), createdTime=Mon Jun 08 22:57:00 CST 2015, time=2015-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2011188, encodeId=866520111887c, content=<a href='/topic/show?id=840d1e300e5' target=_blank style='color:#2F92EE;'>#TET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17300, encryptionId=840d1e300e5, topicName=TET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cc52251, createdName=yhy100200, createdTime=Sat Aug 15 18:57:00 CST 2015, time=2015-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=22827, encodeId=a6b92282ecc, content=不错哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Wed May 06 22:15:00 CST 2015, time=2015-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=22733, encodeId=3f3f22e3356, content=不错~~, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=chaie1217, createdTime=Wed May 06 12:59:00 CST 2015, time=2015-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=22698, encodeId=b257226989b, content=这个视角很特殊, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=61.171.184.**, createdTime=Tue May 05 23:11:00 CST 2015, time=2015-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=22670, encodeId=83b7226e08b, content=了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3yz0JbjHQ7nicJU7lHMOu0Itf3Zv3VBzEvK3k4AFPBXhiaxIRNGVI33GicoRXQEjkaasjdlWKwZuwcyhDP9Jibqt5ct/0, createdBy=f1281613275, createdName=zhouanxiu, createdTime=Tue May 05 22:49:00 CST 2015, time=2015-05-05, status=1, ipAttribution=)]
    2015-08-15 yhy100200
  3. [GetPortalCommentsPageByObjectIdResponse(id=2043850, encodeId=16262043850cd, content=<a href='/topic/show?id=8513126129d' target=_blank style='color:#2F92EE;'>#NEC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12612, encryptionId=8513126129d, topicName=NEC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1ac22500003, createdName=1249842em09(暂无昵称), createdTime=Mon Jun 08 22:57:00 CST 2015, time=2015-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2011188, encodeId=866520111887c, content=<a href='/topic/show?id=840d1e300e5' target=_blank style='color:#2F92EE;'>#TET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17300, encryptionId=840d1e300e5, topicName=TET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cc52251, createdName=yhy100200, createdTime=Sat Aug 15 18:57:00 CST 2015, time=2015-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=22827, encodeId=a6b92282ecc, content=不错哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Wed May 06 22:15:00 CST 2015, time=2015-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=22733, encodeId=3f3f22e3356, content=不错~~, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=chaie1217, createdTime=Wed May 06 12:59:00 CST 2015, time=2015-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=22698, encodeId=b257226989b, content=这个视角很特殊, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=61.171.184.**, createdTime=Tue May 05 23:11:00 CST 2015, time=2015-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=22670, encodeId=83b7226e08b, content=了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3yz0JbjHQ7nicJU7lHMOu0Itf3Zv3VBzEvK3k4AFPBXhiaxIRNGVI33GicoRXQEjkaasjdlWKwZuwcyhDP9Jibqt5ct/0, createdBy=f1281613275, createdName=zhouanxiu, createdTime=Tue May 05 22:49:00 CST 2015, time=2015-05-05, status=1, ipAttribution=)]
    2015-05-06 huaxipanxing

    不错哦

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=2043850, encodeId=16262043850cd, content=<a href='/topic/show?id=8513126129d' target=_blank style='color:#2F92EE;'>#NEC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12612, encryptionId=8513126129d, topicName=NEC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1ac22500003, createdName=1249842em09(暂无昵称), createdTime=Mon Jun 08 22:57:00 CST 2015, time=2015-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2011188, encodeId=866520111887c, content=<a href='/topic/show?id=840d1e300e5' target=_blank style='color:#2F92EE;'>#TET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17300, encryptionId=840d1e300e5, topicName=TET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cc52251, createdName=yhy100200, createdTime=Sat Aug 15 18:57:00 CST 2015, time=2015-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=22827, encodeId=a6b92282ecc, content=不错哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Wed May 06 22:15:00 CST 2015, time=2015-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=22733, encodeId=3f3f22e3356, content=不错~~, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=chaie1217, createdTime=Wed May 06 12:59:00 CST 2015, time=2015-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=22698, encodeId=b257226989b, content=这个视角很特殊, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=61.171.184.**, createdTime=Tue May 05 23:11:00 CST 2015, time=2015-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=22670, encodeId=83b7226e08b, content=了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3yz0JbjHQ7nicJU7lHMOu0Itf3Zv3VBzEvK3k4AFPBXhiaxIRNGVI33GicoRXQEjkaasjdlWKwZuwcyhDP9Jibqt5ct/0, createdBy=f1281613275, createdName=zhouanxiu, createdTime=Tue May 05 22:49:00 CST 2015, time=2015-05-05, status=1, ipAttribution=)]
    2015-05-06 chaie1217

    不错~~

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=2043850, encodeId=16262043850cd, content=<a href='/topic/show?id=8513126129d' target=_blank style='color:#2F92EE;'>#NEC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12612, encryptionId=8513126129d, topicName=NEC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1ac22500003, createdName=1249842em09(暂无昵称), createdTime=Mon Jun 08 22:57:00 CST 2015, time=2015-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2011188, encodeId=866520111887c, content=<a href='/topic/show?id=840d1e300e5' target=_blank style='color:#2F92EE;'>#TET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17300, encryptionId=840d1e300e5, topicName=TET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cc52251, createdName=yhy100200, createdTime=Sat Aug 15 18:57:00 CST 2015, time=2015-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=22827, encodeId=a6b92282ecc, content=不错哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Wed May 06 22:15:00 CST 2015, time=2015-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=22733, encodeId=3f3f22e3356, content=不错~~, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=chaie1217, createdTime=Wed May 06 12:59:00 CST 2015, time=2015-05-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=22698, encodeId=b257226989b, content=这个视角很特殊, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=61.171.184.**, createdTime=Tue May 05 23:11:00 CST 2015, time=2015-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=22670, encodeId=83b7226e08b, content=了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3yz0JbjHQ7nicJU7lHMOu0Itf3Zv3VBzEvK3k4AFPBXhiaxIRNGVI33GicoRXQEjkaasjdlWKwZuwcyhDP9Jibqt5ct/0, createdBy=f1281613275, createdName=zhouanxiu, createdTime=Tue May 05 22:49:00 CST 2015, time=2015-05-05, status=1, ipAttribution=)]
    2015-05-05 61.171.184.**

    这个视角很特殊

    0

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    2015-05-05 zhouanxiu

    了解

    0

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系统性血管炎(SV)是一种非常见疾病,在育龄期的女性很少出现该疾病,因此目前临床上关于该疾病女性妊娠的数据极少,只有少部分回顾性的资料。因此Fredi M等人对该病发生在妊娠前、妊娠期、妊娠后时候的母儿结局做了项研究。

Sleep:同样是睡眠质量下降,差异咋就那么大呢?

妊娠期是女性一生中的特殊时期,由于妊娠导致的各种生理改变,使得孕妇睡觉不安慰,睡眠质量直线下降。

Diabet Med:孕妇抑郁可能导致早产

Callesen NF等人进行了一项研究探究糖尿病合并妊娠孕妇在孕早期时其精神健康状态与不良妊娠结局如早产的关系。该研究主要调查了孕早期与健康相关的生活质量情况、焦虑、抑郁、精神力控制这几个方面对不良妊娠结局的影响

JECH:为了新生儿的健康,妈妈请多念书

目前欧洲的主要重点之一是努力减少卫生不公平现象,让所有人有个健康的生活开始。该任务对未来几代人的健康都将有着极其重要的意义。但是目前在很多欧洲国家关于新生儿健康不平等的信息或证据少之又少。因此Ruiz M 等人对12个欧洲国家,共计75296名新生儿的前瞻性队列研究进行了meta分析,以评估孕妇教育程度与早产和小于胎龄儿风险间关系。通过回归模型评估每个队列并进行meta分析比较衡量队列间异质性。这

Pediatr Infect Dis J:孕期抗逆转录病毒治疗与小于胎龄儿

世界上每天大约有1500名儿童感染艾滋病毒,其中大部分是在母亲怀孕和分娩时被感染的新生胎儿。通常HIV孕妇可以使用抗逆转录病毒(ARV)治疗以最大限度的减少垂直传播风险。先前有研究报道孕期抗逆转录病毒(ARV)治疗和小于胎龄儿(SGA)间有着某种关系,但目前的报道均不能完全阐明该联系。因此Phiri K等人收集了田纳西州相关医学记录,纳入1994-2009年间HIV孕妇。根据诊断、ARV处方、CD