Diabetes Care:痛性糖尿病神经病变与夜间血压升高有关

2014-07-18 伊文 中华医学会糖尿病学分会

一项来自意大利的小规模研究显示,有痛性糖尿病多发神经病变(PDPN)的患者夜间收缩压水平较高。因此,研究者认为,PDPN应被视作心血管高危因素。(Diabetes Care. 2014年6月26日在线版)该研究纳入113例糖尿病患者,其中34例有PDPN,33例伴无痛DPN,46例无DPN。研究者发现,伴PDPN的患者夜间收缩压水平明显高于其他两组受试者,而日间和夜间收缩压差较小,舒张压水平较低。

一项来自意大利的小规模研究显示,有痛性糖尿病多发神经病变(PDPN)的患者夜间收缩压水平较高。因此,研究者认为,PDPN应被视作心血管高危因素,文章发表在Diabetes Care. 2014年6月26日在线版)

该研究纳入113例糖尿病患者,其中34例有PDPN,33例伴无痛DPN,46例无DPN。研究者发现,伴PDPN的患者夜间收缩压水平(130.4 ± 15.6 mmHg) 明显高于无DPN组((119.9 ± 10.6 mmHg; P < 0.0001),以及无痛DPN(124.2 ± 12.3 mmHg; P < 0.05),而日间和夜间收缩压差较小 (5.5 ± 6.5 vs. 8.6 ± 7.7%; P < 0.05) ,舒张压水平较低。逐步回归分析显示,除体位性低血压和阻塞性睡眠呼吸暂停风险较高外,PDPN是日夜收缩压差和 舒张压差以及夜间收缩压水平的独立决定因素,可能意味着PDPN患者有高心血管风险。

原始出处:

D'Amato C, Morganti R, Di Gennaro F, Greco C, Marfia GA, Spallone V.A Novel Association Between Nondipping and Painful Diabetic Polyneuropathy.Diabetes Care. 2014 Jun 26. pii: DC_140528.

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    2015-04-11 x35042875

    糖尿病肾病进展风险的关系没有发现。

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1901232, encodeId=66a719012320e, content=<a href='/topic/show?id=c097591ed5' target=_blank style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Wed Nov 05 07:46:00 CST 2014, time=2014-11-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1636912, encodeId=1328163691257, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Wed Oct 29 23:46:00 CST 2014, time=2014-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=20697, encodeId=4d422069ee1, content=糖尿病肾病进展风险的关系没有发现。, beContent=null, objectType=article, channel=null, level=null, likeNumber=177, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sat Apr 11 23:31:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1759474, encodeId=a8671e5947485, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Wed Jul 01 07:46:00 CST 2015, time=2015-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1718929, encodeId=9eb71e189291c, content=<a href='/topic/show?id=32b888935ca' target=_blank style='color:#2F92EE;'>#血压升高#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=88935, encryptionId=32b888935ca, topicName=血压升高)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c86e32676392, createdName=zhang92571, createdTime=Sun Sep 14 23:46:00 CST 2014, time=2014-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1322548, encodeId=984b1322548f0, content=<a href='/topic/show?id=c204e6750f7' target=_blank style='color:#2F92EE;'>#糖尿病神经病变#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76750, encryptionId=c204e6750f7, topicName=糖尿病神经病变)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=03e7496, createdName=楚钟, createdTime=Sun Jul 20 01:46:00 CST 2014, time=2014-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1491223, encodeId=660f1491223aa, content=<a href='/topic/show?id=5316e4387aa' target=_blank style='color:#2F92EE;'>#神经病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74387, encryptionId=5316e4387aa, topicName=神经病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1ab48885684, createdName=axin012, createdTime=Sun Jul 20 01:46:00 CST 2014, time=2014-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1500320, encodeId=ba8a1500320c2, content=<a href='/topic/show?id=ecdfe438970' target=_blank style='color:#2F92EE;'>#神经病变#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74389, encryptionId=ecdfe438970, topicName=神经病变)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0ea69427176, createdName=lingaifan, createdTime=Sun Jul 20 01:46:00 CST 2014, time=2014-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1589038, encodeId=e8491589038e1, content=<a href='/topic/show?id=2b504354483' target=_blank style='color:#2F92EE;'>#夜间血压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43544, encryptionId=2b504354483, topicName=夜间血压)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3efb17667459, createdName=cathymary, createdTime=Sun Jul 20 01:46:00 CST 2014, time=2014-07-20, status=1, ipAttribution=)]
    2015-07-01 智智灵药
  5. [GetPortalCommentsPageByObjectIdResponse(id=1901232, encodeId=66a719012320e, content=<a href='/topic/show?id=c097591ed5' target=_blank style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Wed Nov 05 07:46:00 CST 2014, time=2014-11-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1636912, encodeId=1328163691257, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Wed Oct 29 23:46:00 CST 2014, time=2014-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=20697, encodeId=4d422069ee1, content=糖尿病肾病进展风险的关系没有发现。, beContent=null, objectType=article, channel=null, level=null, likeNumber=177, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sat Apr 11 23:31:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1759474, encodeId=a8671e5947485, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Wed Jul 01 07:46:00 CST 2015, time=2015-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1718929, encodeId=9eb71e189291c, content=<a href='/topic/show?id=32b888935ca' target=_blank style='color:#2F92EE;'>#血压升高#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=88935, encryptionId=32b888935ca, topicName=血压升高)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c86e32676392, createdName=zhang92571, createdTime=Sun Sep 14 23:46:00 CST 2014, time=2014-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1322548, encodeId=984b1322548f0, content=<a href='/topic/show?id=c204e6750f7' target=_blank style='color:#2F92EE;'>#糖尿病神经病变#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76750, encryptionId=c204e6750f7, topicName=糖尿病神经病变)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=03e7496, createdName=楚钟, createdTime=Sun Jul 20 01:46:00 CST 2014, time=2014-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1491223, encodeId=660f1491223aa, content=<a href='/topic/show?id=5316e4387aa' target=_blank style='color:#2F92EE;'>#神经病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74387, encryptionId=5316e4387aa, topicName=神经病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1ab48885684, createdName=axin012, createdTime=Sun Jul 20 01:46:00 CST 2014, time=2014-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1500320, encodeId=ba8a1500320c2, content=<a href='/topic/show?id=ecdfe438970' target=_blank style='color:#2F92EE;'>#神经病变#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74389, encryptionId=ecdfe438970, topicName=神经病变)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0ea69427176, createdName=lingaifan, createdTime=Sun Jul 20 01:46:00 CST 2014, time=2014-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1589038, encodeId=e8491589038e1, content=<a href='/topic/show?id=2b504354483' target=_blank style='color:#2F92EE;'>#夜间血压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43544, encryptionId=2b504354483, topicName=夜间血压)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3efb17667459, createdName=cathymary, createdTime=Sun Jul 20 01:46:00 CST 2014, time=2014-07-20, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1901232, encodeId=66a719012320e, content=<a href='/topic/show?id=c097591ed5' target=_blank style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Wed Nov 05 07:46:00 CST 2014, time=2014-11-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1636912, encodeId=1328163691257, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Wed Oct 29 23:46:00 CST 2014, time=2014-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=20697, encodeId=4d422069ee1, content=糖尿病肾病进展风险的关系没有发现。, beContent=null, objectType=article, channel=null, level=null, likeNumber=177, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sat Apr 11 23:31:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1759474, encodeId=a8671e5947485, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Wed Jul 01 07:46:00 CST 2015, time=2015-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1718929, encodeId=9eb71e189291c, content=<a href='/topic/show?id=32b888935ca' target=_blank style='color:#2F92EE;'>#血压升高#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=88935, encryptionId=32b888935ca, topicName=血压升高)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c86e32676392, createdName=zhang92571, createdTime=Sun Sep 14 23:46:00 CST 2014, time=2014-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1322548, encodeId=984b1322548f0, content=<a href='/topic/show?id=c204e6750f7' target=_blank style='color:#2F92EE;'>#糖尿病神经病变#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76750, encryptionId=c204e6750f7, topicName=糖尿病神经病变)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=03e7496, createdName=楚钟, createdTime=Sun Jul 20 01:46:00 CST 2014, time=2014-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1491223, encodeId=660f1491223aa, content=<a href='/topic/show?id=5316e4387aa' target=_blank style='color:#2F92EE;'>#神经病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74387, encryptionId=5316e4387aa, topicName=神经病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1ab48885684, createdName=axin012, createdTime=Sun Jul 20 01:46:00 CST 2014, time=2014-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1500320, encodeId=ba8a1500320c2, content=<a href='/topic/show?id=ecdfe438970' target=_blank style='color:#2F92EE;'>#神经病变#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74389, encryptionId=ecdfe438970, topicName=神经病变)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0ea69427176, createdName=lingaifan, createdTime=Sun Jul 20 01:46:00 CST 2014, time=2014-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1589038, encodeId=e8491589038e1, content=<a href='/topic/show?id=2b504354483' target=_blank style='color:#2F92EE;'>#夜间血压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43544, encryptionId=2b504354483, topicName=夜间血压)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3efb17667459, createdName=cathymary, createdTime=Sun Jul 20 01:46:00 CST 2014, time=2014-07-20, status=1, ipAttribution=)]
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    2014-07-20 axin012
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