FRONT AGING NEUROSCI:规律运动可延缓大脑萎缩

2016-09-01 MedSci MedSci原创

马里兰大学(UMD)的研究人员通过进行后研究发现,平素身体健康的老年人若仅停止锻炼10天左右,大脑中负责机体思考、学习、记忆的重要区域如海马体等的血流量便会明显下降。研究结果发表在Frontiers in Aging Neuroscience。这表明身体健康和认知健康之间有密切关联。 研究人员既往致力于寻找长期耐力运动对改善民众脑血管健康和对海马体的积极作用,但是并不清楚如果停止运动后则这些积极

马里兰大学(UMD)的研究人员通过研究发现,平素身体健康的老年人若仅停止锻炼10天左右,大脑中负责机体思考、学习、记忆的重要区域如海马体等的血流量便会明显下降。研究结果发表在Frontiers in Aging Neuroscience。这表明运动和认知健康之间有密切关联。


研究人员既往致力于寻找长期耐力运动对改善民众脑血管健康和对海马体的积极作用,但是并不清楚如果停止运动后则这些积极作用是否还会存在。 

UMD运动学副教授J.Carson Smith博士指出,众所周知,海马体对机体维持学习和记忆功能很重要。对小鼠和大鼠的研究表明,规律锻炼可促进大脑中新血管的形成和脑细胞的再生。此外,他指出,规律运动可延缓或避免海马体的萎缩。仅仅停止运动十天,便会出现海马体血流量的明显下降,研究人员指出,这表明规律运动对维持大脑功能的重要性。

研究人员对一些平时身体健康、年龄范围为50-89岁(平均为61岁)的老年人进行了调查,并通过使用磁共振成像(MRI)收集了他们停止运动前和停止运动十天后的脑血流量数据。 研究参与者均主要为运动员,研究人员认为不应单纯地认为他们是进行高强度运动的普通运动员。他们的最大摄氧量位居同年龄段的前10%,他们进行耐力运动的平均时间为29年,并参加了一些全国性和地区性的大小型比赛。在研究开始之前,他们依然保持每周运动5天,每周跑步距离为59千米。

结果显示,参与者大脑中八个部位——包括左右海马体的血流量明显降低,此外还包括部分“默认模式网络”。然而,研究人员通过对参与者进行语言测试发现参与者的认知功能无显著变化。

研究人员表示,老年人需要进行规律锻炼,这样可延缓大脑海马体的萎缩进程,可提高其认知功能,并降低机体患慢性疾病的风险。 

原始出处: 

 
[2] Alfonso J. Alfini et al. Hippocampal and Cerebral Blood Flow after Exercise Cessation in Master Athletes. Frontiers in Aging Neuroscience. 2016 August 5.
 
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    2017-07-25 chendoc252
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    2016-09-06 李东泽

    很好,不错,以后会多学习

    0

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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=109548, encodeId=fa9110954816, content=继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Fri Sep 02 11:38:00 CST 2016, time=2016-09-02, status=1, ipAttribution=)]
    2016-09-05 李东泽

    很好,不错,以后会多学习

    0

  4. 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createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2017/04/21/72142930668371951a41ef4ea4b233e6.jpg, createdBy=dcbc1715228, createdName=刘煜, createdTime=Mon Sep 05 06:24:00 CST 2016, time=2016-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=110360, encodeId=02bb11036040, content=值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5e291719269, createdName=大旺旺, createdTime=Sat Sep 03 13:12:00 CST 2016, time=2016-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1364125, encodeId=0072136412595, content=<a href='/topic/show?id=7c5615628ad' target=_blank style='color:#2F92EE;'>#ROS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15628, encryptionId=7c5615628ad, topicName=ROS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=acc3210, createdName=lsndxfj, createdTime=Sat Sep 03 01:56:00 CST 2016, time=2016-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1401203, encodeId=1fdb140120370, content=<a href='/topic/show?id=3405850e3f4' target=_blank style='color:#2F92EE;'>#脑萎缩#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85073, encryptionId=3405850e3f4, topicName=脑萎缩)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/xdmCjlickSzn2cxg75bTZeYl2VYrTV6hibyMlic5XVFkibQbmFB7tK72afyxE4iclBhv7qd91qSk8Q6yicAcmErXRFxQ/132, createdBy=2c5d2304811, createdName=smartjoy, createdTime=Sat Sep 03 01:56:00 CST 2016, time=2016-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1625408, encodeId=48711625408ec, content=<a 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=109548, encodeId=fa9110954816, content=继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Fri Sep 02 11:38:00 CST 2016, time=2016-09-02, status=1, ipAttribution=)]
    2016-09-05 刘煜

    生命在于运动。

    0

  5. 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topicName=ROS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=acc3210, createdName=lsndxfj, createdTime=Sat Sep 03 01:56:00 CST 2016, time=2016-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1401203, encodeId=1fdb140120370, content=<a href='/topic/show?id=3405850e3f4' target=_blank style='color:#2F92EE;'>#脑萎缩#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85073, encryptionId=3405850e3f4, topicName=脑萎缩)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/xdmCjlickSzn2cxg75bTZeYl2VYrTV6hibyMlic5XVFkibQbmFB7tK72afyxE4iclBhv7qd91qSk8Q6yicAcmErXRFxQ/132, createdBy=2c5d2304811, createdName=smartjoy, createdTime=Sat Sep 03 01:56:00 CST 2016, time=2016-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1625408, encodeId=48711625408ec, content=<a href='/topic/show?id=dfe143964e4' target=_blank style='color:#2F92EE;'>#大脑萎缩#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43964, encryptionId=dfe143964e4, topicName=大脑萎缩)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=48aa20754836, createdName=gracezdd, createdTime=Sat Sep 03 01:56:00 CST 2016, time=2016-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=109547, encodeId=1f3c10954ed9, content=继续学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Fri Sep 02 11:38:00 CST 2016, time=2016-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=109548, encodeId=fa9110954816, content=继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Fri Sep 02 11:38:00 CST 2016, time=2016-09-02, status=1, ipAttribution=)]
    2016-09-03 大旺旺

    值得学习

    0

  6. 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topicName=ROS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=acc3210, createdName=lsndxfj, createdTime=Sat Sep 03 01:56:00 CST 2016, time=2016-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1401203, encodeId=1fdb140120370, content=<a href='/topic/show?id=3405850e3f4' target=_blank style='color:#2F92EE;'>#脑萎缩#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85073, encryptionId=3405850e3f4, topicName=脑萎缩)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/xdmCjlickSzn2cxg75bTZeYl2VYrTV6hibyMlic5XVFkibQbmFB7tK72afyxE4iclBhv7qd91qSk8Q6yicAcmErXRFxQ/132, createdBy=2c5d2304811, createdName=smartjoy, createdTime=Sat Sep 03 01:56:00 CST 2016, time=2016-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1625408, encodeId=48711625408ec, content=<a 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=109548, encodeId=fa9110954816, content=继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Fri Sep 02 11:38:00 CST 2016, time=2016-09-02, status=1, ipAttribution=)]
    2016-09-03 lsndxfj
  7. 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createdBy=8aa81937526, createdName=李东泽, createdTime=Tue Sep 06 16:13:00 CST 2016, time=2016-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=111338, encodeId=b53611133882, content=很好,不错,以后会多学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Mon Sep 05 10:31:00 CST 2016, time=2016-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=111081, encodeId=fd4011108160, content=生命在于运动。, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, 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topicName=ROS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=acc3210, createdName=lsndxfj, createdTime=Sat Sep 03 01:56:00 CST 2016, time=2016-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1401203, encodeId=1fdb140120370, content=<a href='/topic/show?id=3405850e3f4' target=_blank style='color:#2F92EE;'>#脑萎缩#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85073, encryptionId=3405850e3f4, topicName=脑萎缩)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/xdmCjlickSzn2cxg75bTZeYl2VYrTV6hibyMlic5XVFkibQbmFB7tK72afyxE4iclBhv7qd91qSk8Q6yicAcmErXRFxQ/132, createdBy=2c5d2304811, createdName=smartjoy, createdTime=Sat Sep 03 01:56:00 CST 2016, time=2016-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1625408, encodeId=48711625408ec, content=<a 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=109548, encodeId=fa9110954816, content=继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Fri Sep 02 11:38:00 CST 2016, time=2016-09-02, status=1, ipAttribution=)]
  8. 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topicName=ROS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=acc3210, createdName=lsndxfj, createdTime=Sat Sep 03 01:56:00 CST 2016, time=2016-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1401203, encodeId=1fdb140120370, content=<a href='/topic/show?id=3405850e3f4' target=_blank style='color:#2F92EE;'>#脑萎缩#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85073, encryptionId=3405850e3f4, topicName=脑萎缩)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/xdmCjlickSzn2cxg75bTZeYl2VYrTV6hibyMlic5XVFkibQbmFB7tK72afyxE4iclBhv7qd91qSk8Q6yicAcmErXRFxQ/132, createdBy=2c5d2304811, createdName=smartjoy, createdTime=Sat Sep 03 01:56:00 CST 2016, time=2016-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1625408, encodeId=48711625408ec, content=<a 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=109548, encodeId=fa9110954816, content=继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Fri Sep 02 11:38:00 CST 2016, time=2016-09-02, status=1, ipAttribution=)]
  9. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=109548, encodeId=fa9110954816, content=继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Fri Sep 02 11:38:00 CST 2016, time=2016-09-02, status=1, ipAttribution=)]
    2016-09-02 doctorJiangchao

    继续学习

    0

  10. 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