JCO:术中冰冻病理诊断指导亚肺叶切除术精准切除

2015-12-04 MedSci MedSci原创

复旦大学附属肿瘤医院胸部肿瘤多学科综合诊治团队准确描述并定义了周围型肺腺癌的术中冰冻病理诊断,同时以此提出了兼具微创、精准和疗效三位一体亚肺叶切除手术方式的精准指征。相关成果日前在线发表于《临床肿瘤学杂志》。据上述团队首席专家陈海泉介绍,团队中的放射介入医师在CT的精确引导下,为每一例肺小结节患者通过胸外插入“带钩钢丝”,从而为外科医生术中精确找到病灶作好“位置标记”。此项技术开展近8年来,已完成

复旦大学附属肿瘤医院胸部肿瘤多学科综合诊治团队准确描述并定义了周围型肺腺癌的术中冰冻病理诊断,同时以此提出了兼具微创、精准和疗效三位一体亚肺叶切除手术方式的精准指征。相关成果日前在线发表于《临床肿瘤学杂志》。


据上述团队首席专家陈海泉介绍,团队中的放射介入医师在CT的精确引导下,为每一例肺小结节患者通过胸外插入“带钩钢丝”,从而为外科医生术中精确找到病灶作好“位置标记”。此项技术开展近8年来,已完成患者1000余例,定位精准率达99%以上;同时,由于取下的病变组织完整,为病理科作出明确诊断创造了条件。

“术中,我们不仅追求手术切口的大小、打洞的数量,更关键的是能根据术中的病理结果精准地进行病变组织切除,减少术中器械游离时对正常组织造成的伤害。”陈海泉表示。

据统计,肿瘤医院在国内率先开展全腔镜下Ivor Lewis食管癌根治术、胸腔镜下肺癌根治术、保留肌肉的小切口开胸肺叶切除术等微创手术。目前,累计完成超过1万多例胸部肿瘤微创手术。

陈海泉介绍说,此项成果具有里程碑意义:“首先,精确的术中冰冻病理诊断对于早期周围型肺腺癌患者手术方式的选择具有重要指导价值;其次,对于复发低危的周围型肺腺癌患者,行亚肺叶切除术可在保证疗效的前提下,精确划定手术范围,将内部脏器的损伤降至最低,从而最大程度地保留肺功能,提高手术安全性。”

原始出处:

Liu S, Wang R, Zhang Y, Li Y, Cheng C, Pan Y, Xiang J, Zhang Y, Chen H, Sun Y.Precise Diagnosis of Intraoperative Frozen Section Is an Effective Method to Guide Resection Strategy for Peripheral Small-Sized Lung Adenocarcinoma.J Clin Oncol. 2015 Nov 23. pii: JCO634907.

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    2016-08-27 李东泽

    这篇资讯带给我们新知识,启发新思维,不论是科研还是临床工作都有很大的帮助。。。

    0

  3. 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    2016-08-12 lidong40
  4. 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encryptionId=67c5319121e, topicName=切除术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9d8a96, createdName=doctorzheng, createdTime=Sat Nov 19 05:16:00 CST 2016, time=2016-11-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=48896, encodeId=f06c48896d9, content=好文章,值得收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=158, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc301610909, createdName=hixiaoluo, createdTime=Sun Dec 27 08:30:00 CST 2015, time=2015-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=45545, encodeId=ad284554533, content=历害, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4bfa83595, createdName=jetleo, createdTime=Fri Dec 11 13:00:00 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  5. [GetPortalCommentsPageByObjectIdResponse(id=1987779, encodeId=7d6d198e7797c, content=<a href='/topic/show?id=93d8243089c' target=_blank style='color:#2F92EE;'>#亚肺叶#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=24308, encryptionId=93d8243089c, topicName=亚肺叶)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f984116, createdName=kzlchina, createdTime=Fri Apr 15 10:16:00 CST 2016, time=2016-04-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=105906, encodeId=6dd61059060a, content=这篇资讯带给我们新知识,启发新思维,不论是科研还是临床工作都有很大的帮助。。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, 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authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83epQX9hfEIBiaPg0e9KvLYVBCSGYydH6K6OQxBh3RaOC0TYP9HYy2v0XdHib1LFnZNU5Siak0P8oh8Aqw/132, createdBy=acd92440184, createdName=shijzhiewnjhch, createdTime=Sun Dec 06 14:16:00 CST 2015, time=2015-12-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1556425, encodeId=d1e0155642535, content=<a href='/topic/show?id=a9b0820898c' target=_blank style='color:#2F92EE;'>#肺叶切除#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82089, encryptionId=a9b0820898c, topicName=肺叶切除)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=727d14772225, createdName=zhangj7113, createdTime=Sun Dec 06 14:16:00 CST 2015, time=2015-12-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44926, encodeId=37374492690, content=号, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=89451666648, createdName=1211暖暖, createdTime=Sat Dec 05 21:13:00 CST 2015, time=2015-12-05, status=1, ipAttribution=)]
    2015-12-27 hixiaoluo

    好文章,值得收藏

    0

  6. 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channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=89451666648, createdName=1211暖暖, createdTime=Sat Dec 05 21:13:00 CST 2015, time=2015-12-05, status=1, ipAttribution=)]
    2015-12-11 jetleo

    历害

    0

  7. 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  9. 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    2015-12-05 1211暖暖

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