JACC:心肌的顺应性能较射血分数更高地反映心室收缩功能

2017-08-15 nanchao.H MedSci原创

保留型左室射血分数(EF)和心肌顺应性下降经常出现在肥厚型心肌病、缺血性心脏病和糖尿病等患者中。近日,在国际心血管权威杂志JACC上发表了一篇旨在通过数学和超声心动图结合的方法分析评估EF和心肌顺应性的这种不一致性。来自一个椭圆形的左室模型的解析方程显示出EF和4个参数之间的关系:整体纵向应变(GLS),整体圆周应变(GCS)、壁厚和短轴直径。通过心超对100例EF为16%-72%的研究对象进行该

保留型左室射血分数(EF)和心肌顺应性下降经常出现在肥厚型心肌病、缺血性心脏病和糖尿病等患者中。近日,在国际心血管权威杂志JACC上发表了一篇旨在通过数学和超声心动图结合的方法分析评估EF和心肌顺应性的这种不一致性。来自一个椭圆形的左室模型的解析方程显示出EF和4个参数之间的关系:整体纵向应变(GLS),整体圆周应变(GCS)、壁厚和短轴直径。通过心超对100例EF为16%-72%的研究对象进行该4个参数的测量来确定该解析方程式,并将模型预测的EF与实际测量的EF进行对比。研究结果显示,模型预测的EF与实际测量的EF高度吻合(r = 0.95)。模型结果显示GCS预测EF的效果大于GLS的两倍,GLS的减少可以通过GCS的升高或壁厚来补偿。此外,该模型进一步阐明了EF是如何在心室壁增厚的情况下维持不变的,尽管心脏的长轴和圆周均有所减少。研究结果表明,心脏在轻度变形的情况下维持射血分数不变是可以通过数学几何参数解释的,因此,心肌顺应性能更好地反映患者的心脏收缩功能。原始出处:Thomas M et al.Geometry as a Confounder When Assessing Ve

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    2018-03-18 hbwxf
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    2017-08-18 1e0ece0dm09(暂无匿称)

    谢谢分享

    0

  3. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04f22055142, createdName=131****2916, createdTime=Tue Aug 15 23:13:44 CST 2017, time=2017-08-15, status=1, ipAttribution=)]
    2017-08-16 明月清辉

    谢谢分享,学习了

    0

  5. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04f22055142, createdName=131****2916, createdTime=Tue Aug 15 23:13:44 CST 2017, time=2017-08-15, status=1, ipAttribution=)]
    2017-08-16 Y—xianghai

    学习了新知识

    0

  6. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04f22055142, createdName=131****2916, createdTime=Tue Aug 15 23:13:44 CST 2017, time=2017-08-15, status=1, ipAttribution=)]
    2017-08-16 忠诚向上

    好好学习看看

    0

  7. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04f22055142, createdName=131****2916, createdTime=Tue Aug 15 23:13:44 CST 2017, time=2017-08-15, status=1, ipAttribution=)]
    2017-08-16 刘煜

    学习了谢谢分享

    0

  8. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04f22055142, createdName=131****2916, createdTime=Tue Aug 15 23:13:44 CST 2017, time=2017-08-15, status=1, ipAttribution=)]
    2017-08-16 半夏微凉

    学习了谢谢分享

    0

  9. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04f22055142, createdName=131****2916, createdTime=Tue Aug 15 23:13:44 CST 2017, time=2017-08-15, status=1, ipAttribution=)]
    2017-08-16 189****1577

    值得推荐一下

    0

  10. 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    2017-08-15 131****2916

    不错的文章值得学习

    0

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