Leuk Lymphoma:AML青少年和年轻人生存期存在种族差异

2017-05-02 梁舒瑶;常路 环球医学

很少有研究检测了种族对急性髓性白血病(AML)的青少年和年轻人(AYA)生存期的影响。2017年5月,发表在《Leuk Lymphoma》的一项使用美国国家癌症数据库的回顾性研究对此进行分析。

很少有研究检测了种族对急性髓性白血病(AML)的青少年和年轻人(AYA)生存期的影响。2017年5月,发表在《Leuk Lymphoma》的一项使用美国国家癌症数据库的回顾性研究对此进行分析。

该研究对美国国家癌症数据库中的2001~2011年确诊为AML的15~39岁的患者(排除了急性早幼粒细胞白血病)进行分析。根据民族的不同,研究人员检测了总生存期(OS),确定了以下3个时间段的OS趋势:2001~2004、2005~2008、2009~2011。研究人员识别出8684名患者,中位随访62.8个月。多变量分析表明,与白人相比,黑人具有显着性更差的OS(HR,1.21;95% CI,1.11~1.32),西班牙裔具有显着性更好的OS(HR,0.90;95% CI,0.82~0.99)。仅白人随着时间可获得OS的改善,3个时间段的1年生存率分别为69、72和74个月(P<0.01)。

研究人员发现了AML的AYA患者的OS具有显着的种族差异。进一步的研究应该检测促成这些差异的医生和患者的医疗递送因素。

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    2017-05-07 1771ae4158m

    学习一下很不错

    0

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    2017-05-05 1e145228m78(暂无匿称)

    学习了,谢谢作者分享!

    0

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createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Fri May 05 05:13:08 CST 2017, time=2017-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=193882, encodeId=521a1938820a, content=种族差异,年龄,地域,性别, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K3znicMkicI94Wia7Jq1NMQAXYyWibHfz7XEaqq8FZufAK6QGDOgG5hoFDL0cp2dK7aMBYu8GMicticgP0/0, createdBy=94221957302, createdName=铭记心中。。, createdTime=Fri May 05 00:34:00 CST 2017, time=2017-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1353562, encodeId=a4691353562ca, content=<a href='/topic/show?id=29e1e4781f1' target=_blank style='color:#2F92EE;'>#种族差异#</a>, 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=193330, encodeId=364219333095, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfBfgWn9nXBgH1sNSiaOAKhsKpN40jDHQKqcRzovau5VibLvREN8uxnu9sKoScBicHSiaDMmbveibFdrBiaD4k4IOPwlG/0, createdBy=b5d11730951, createdName=Jackie Li, createdTime=Wed May 03 17:07:34 CST 2017, time=2017-05-03, status=1, ipAttribution=)]
    2017-05-05 ylzr123

    认真学习,把间接经验应用到临床实践中去,然后再总结出新思路。给点赞啦……

    0

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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=193330, encodeId=364219333095, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfBfgWn9nXBgH1sNSiaOAKhsKpN40jDHQKqcRzovau5VibLvREN8uxnu9sKoScBicHSiaDMmbveibFdrBiaD4k4IOPwlG/0, createdBy=b5d11730951, createdName=Jackie Li, createdTime=Wed May 03 17:07:34 CST 2017, time=2017-05-03, status=1, ipAttribution=)]
    2017-05-05 铭记心中。。

    种族差异,年龄,地域,性别

    0

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  8. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=193330, encodeId=364219333095, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfBfgWn9nXBgH1sNSiaOAKhsKpN40jDHQKqcRzovau5VibLvREN8uxnu9sKoScBicHSiaDMmbveibFdrBiaD4k4IOPwlG/0, createdBy=b5d11730951, createdName=Jackie Li, createdTime=Wed May 03 17:07:34 CST 2017, time=2017-05-03, status=1, ipAttribution=)]
    2017-05-04 有备才能无患

    好研究项目

    0

  9. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=193330, encodeId=364219333095, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfBfgWn9nXBgH1sNSiaOAKhsKpN40jDHQKqcRzovau5VibLvREN8uxnu9sKoScBicHSiaDMmbveibFdrBiaD4k4IOPwlG/0, createdBy=b5d11730951, createdName=Jackie Li, createdTime=Wed May 03 17:07:34 CST 2017, time=2017-05-03, status=1, ipAttribution=)]
    2017-05-03 1e1b8538m79(暂无匿称)

    难道是和基因学有关

    0

  10. 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    2017-05-03 Jackie Li

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