Clinical Nutrition: 补充Omega-3脂肪酸、类胡萝卜素和维生素 E 可改善老年人的记忆力

2021-12-11 MedSci原创 MedSci原创

有研究表明,可以对抗大脑的老化,提高记忆力的维生素主要包括维生素B1,维生素B6,维生素B12和叶酸等。

健康的年轻人多摄取ω-3脂肪酸,可帮助改善,提升记忆力,也有越来越多的证据表明,omega-3 脂肪酸 (ω-3FA)、类胡萝卜素和维生素 E 可以提高人类的认知能力。然而,尚未在健康老年个体中研究它们对认知的影响。因此,本研究调查了ω-3FA、类胡萝卜素和维生素 E 补充剂对老年人认知能力的综合影响,评估其是否具有改善记忆力的能力。

 

研究人员要求健康的 65 岁以上的老年人每天服用 1 克鱼油(其中 430 毫克二十二碳六烯酸、90 毫克二十碳五烯酸)、22 毫克类胡萝卜素(10 毫克叶黄素、10 毫克内消旋玉米黄质、2 毫克玉米黄质)和 15 毫克维生素 E进行治疗,同时招募了一批相似的老年患者进行安慰剂对照治疗。

 

 研究结果显示:在补充相关营养制剂24个月后,与接受安慰剂的个体(n=30;年龄 69.77±3.74 岁;70 % 女性)相比,虽然随着工作记忆任务的认知负荷增加,治疗组患者的记忆能力表现优于安慰剂组。与安慰剂相比,在治疗组中也观察到组织类胡萝卜素浓度、血清叶黄素类胡萝卜素浓度和血浆 ω-3FA 浓度的统计学显着改善,因此,额外补充Omega-3脂肪酸、类胡萝卜素和维生素 E是具有一定的益处的。

 

本项研究的结果支持了一个生物学上合理的基本原理,即这些营养素以剂量依赖的方式协同作用,以改善认知健康的老年人的工作记忆。增加类胡萝卜素和 ω-3FA 的营养摄入可能有助于减少晚年认知能力下降和痴呆症的风险。

原始出处 :

Rebecca Power. Et al. Omega-3 fatty acid, carotenoid and vitamin E supplementation improves working memory in older adults: a randomised clinical trial. Clinical Nutrition.2021.

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    2021-12-13 zll0628
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    2021-12-12 查查佳佳

    阅国内外无数文献,经过反复推敲和打磨,改版数十次后精心汇编而成

    0

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