NEJM:罕见原发性伴继发性梅毒感染-案例报道

2016-02-01 chensuo译 MedSci原创

男性,68岁,无既往病史,今因嘴唇上部出现侵蚀性溃疡伴剧烈疼痛而到院就诊(如图A所示)。据该男子主诉嘴唇出现病变已有6周余。体格检查可见,该男子的手及脚(包括手掌和脚掌)可见大范围边界清楚的红斑、鳞屑斑(如图B、C、D所示)。除此以外,未见其他异常症状。实验室检查结果显示梅毒螺旋体颗粒凝集试验阳性(滴度为1:2560;正常值<1:80)、性病研究室试验结果呈阳性(滴度1:8;正常值<1:2)。人类

男性,68岁,无既往病史,今因嘴唇上部出现侵蚀性溃疡伴剧烈疼痛而到院就诊(如图A所示)。据该男子主诉嘴唇出现病变已有6周余。




体格检查可见,该男子的手及脚(包括手掌和脚掌)可见大范围边界清楚的红斑、鳞屑斑(如图B、C、D所示)。除此以外,未见其他异常症状。

实验室检查结果显示梅毒螺旋体颗粒凝集试验阳性(滴度为1:2560;正常值<1:80)、性病研究室试验结果呈阳性(滴度1:8;正常值<1:2)。人类免疫缺陷病毒和肝炎血清学试验均为阴性。免疫印迹分析梅毒特异性IgM和IgG结果阳性。

另外,从嘴唇病变和脚病变部位取活检标本作组织病理学检测分析显示,唇部病变和足溃疡病变为银屑病样增生,两标本均可见丰富CD79a阳性浆细胞和苍白螺旋体。

根据以上所述的临床症状及实验室结果,会诊医师诊断该男子为一期和二期梅毒。

最后,该男子接受了肌肉注射苄星青霉素(每次剂量为2.4×106 IU,共注射3次,间隔时间为4周)。2个月后该男子的症状明显好转,实验室检测滴度也大幅度地降低。

一般情况下,一期和二期梅毒在同一患者身上同时发生是非常罕见的,但是,通过二次感染也有可能导致这种情况的发生。

原始出处:

Michael P. Schön, M.D., and Hans P. Bertsch, Primary and Secondary Syphilis,N Engl J Med 2016; 


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    2016-02-09 feifers
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    2016-08-19 akira明

    谢谢分享。

    0

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encryptionId=3c8662445ce, topicName=梅毒感染)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=zhangpaul93, createdTime=Sat Feb 13 19:10:00 CST 2016, time=2016-02-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71014, encodeId=5452e10148d, content=感谢分享。, beContent=null, objectType=article, channel=null, level=null, likeNumber=138, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=73801651090, createdName=1ddc978cm67(暂无匿称), createdTime=Fri Mar 18 00:09:00 CST 2016, time=2016-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1952650, encodeId=9a37195265026, content=<a href='/topic/show?id=a37ce8961a1' target=_blank style='color:#2F92EE;'>#继发性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78961, encryptionId=a37ce8961a1, topicName=继发性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2317301, createdName=xzw113, createdTime=Fri Nov 04 05:10:00 CST 2016, time=2016-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=63703, encodeId=5e3563e038f, content=头一次听说, beContent=null, objectType=article, channel=null, level=null, likeNumber=135, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160613/IMG575D9886B86721544.jpg, createdBy=07961686486, createdName=1de4921fm57(暂无匿称), createdTime=Mon Feb 08 13:57:00 CST 2016, time=2016-02-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1467115, encodeId=f999146e11519, content=<a href='/topic/show?id=ef32e9539e8' target=_blank style='color:#2F92EE;'>#罕见#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Mon Feb 01 22:28:00 CST 2016, time=2016-02-01, status=1, ipAttribution=)]
  5. 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createdName=jiyangfei, createdTime=Sun May 15 22:10:00 CST 2016, time=2016-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=100610, encodeId=aba2100610de, content=谢谢分享。, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/X5rIibvOT8wIavvRus9ic9ykU2O4icURoYHRZ8GiakmmpTvlumLDRFJCXeUicOeeLAsiaqwWpqYCdsLXeibBv7s48aACA/132, createdBy=509a1938333, createdName=akira明, createdTime=Fri Aug 19 00:22:00 CST 2016, time=2016-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1980770, encodeId=c2461980e70c6, content=<a href='/topic/show?id=3c8662445ce' target=_blank style='color:#2F92EE;'>#梅毒感染#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62445, encryptionId=3c8662445ce, topicName=梅毒感染)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=zhangpaul93, createdTime=Sat Feb 13 19:10:00 CST 2016, time=2016-02-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71014, encodeId=5452e10148d, content=感谢分享。, beContent=null, objectType=article, channel=null, level=null, likeNumber=138, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=73801651090, createdName=1ddc978cm67(暂无匿称), createdTime=Fri Mar 18 00:09:00 CST 2016, time=2016-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1952650, encodeId=9a37195265026, content=<a href='/topic/show?id=a37ce8961a1' target=_blank style='color:#2F92EE;'>#继发性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78961, encryptionId=a37ce8961a1, topicName=继发性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2317301, createdName=xzw113, createdTime=Fri Nov 04 05:10:00 CST 2016, time=2016-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=63703, encodeId=5e3563e038f, content=头一次听说, beContent=null, objectType=article, channel=null, level=null, likeNumber=135, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160613/IMG575D9886B86721544.jpg, createdBy=07961686486, createdName=1de4921fm57(暂无匿称), createdTime=Mon Feb 08 13:57:00 CST 2016, time=2016-02-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1467115, encodeId=f999146e11519, content=<a href='/topic/show?id=ef32e9539e8' target=_blank style='color:#2F92EE;'>#罕见#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79539, encryptionId=ef32e9539e8, topicName=罕见)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=29f36868190, createdName=syscxl, createdTime=Wed Feb 03 02:10:00 CST 2016, time=2016-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=62732, encodeId=5a3962e328a, content=少见, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuK9CDibOwszLoEBg36ZXqzB5NDasNV9GTfFDmBicM1V8hUS4OtTicG3IiaFIKq4wqD23LUxORRJXqjVs/0, createdBy=00e81647535, createdName=I come, createdTime=Tue Feb 02 06:52:00 CST 2016, time=2016-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=62606, encodeId=98886260600, content=值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Mon Feb 01 22:28:00 CST 2016, time=2016-02-01, status=1, ipAttribution=)]
    2016-03-18 1ddc978cm67(暂无匿称)

    感谢分享。

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1724425, encodeId=11911e2442533, content=<a href='/topic/show?id=78ece8958b2' target=_blank style='color:#2F92EE;'>#继发#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78958, encryptionId=78ece8958b2, topicName=继发)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=499d33645837, createdName=feifers, createdTime=Tue Feb 09 06:10:00 CST 2016, time=2016-02-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1846483, encodeId=9b0e184648361, content=<a href='/topic/show?id=d3a33e0306d' target=_blank style='color:#2F92EE;'>#原发性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37030, encryptionId=d3a33e0306d, topicName=原发性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8e4c53, 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topicName=继发性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2317301, createdName=xzw113, createdTime=Fri Nov 04 05:10:00 CST 2016, time=2016-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=63703, encodeId=5e3563e038f, content=头一次听说, beContent=null, objectType=article, channel=null, level=null, likeNumber=135, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160613/IMG575D9886B86721544.jpg, createdBy=07961686486, createdName=1de4921fm57(暂无匿称), createdTime=Mon Feb 08 13:57:00 CST 2016, time=2016-02-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1467115, encodeId=f999146e11519, content=<a href='/topic/show?id=ef32e9539e8' target=_blank style='color:#2F92EE;'>#罕见#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79539, encryptionId=ef32e9539e8, topicName=罕见)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=29f36868190, createdName=syscxl, createdTime=Wed Feb 03 02:10:00 CST 2016, time=2016-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=62732, encodeId=5a3962e328a, content=少见, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuK9CDibOwszLoEBg36ZXqzB5NDasNV9GTfFDmBicM1V8hUS4OtTicG3IiaFIKq4wqD23LUxORRJXqjVs/0, createdBy=00e81647535, createdName=I come, createdTime=Tue Feb 02 06:52:00 CST 2016, time=2016-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=62606, encodeId=98886260600, content=值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Mon Feb 01 22:28:00 CST 2016, time=2016-02-01, status=1, ipAttribution=)]
    2016-11-04 xzw113
  7. 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Mon Feb 01 22:28:00 CST 2016, time=2016-02-01, status=1, ipAttribution=)]
    2016-02-08 1de4921fm57(暂无匿称)

    头一次听说

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1724425, encodeId=11911e2442533, content=<a href='/topic/show?id=78ece8958b2' target=_blank style='color:#2F92EE;'>#继发#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78958, encryptionId=78ece8958b2, topicName=继发)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=499d33645837, createdName=feifers, createdTime=Tue Feb 09 06:10:00 CST 2016, time=2016-02-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1846483, encodeId=9b0e184648361, content=<a href='/topic/show?id=d3a33e0306d' target=_blank style='color:#2F92EE;'>#原发性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37030, encryptionId=d3a33e0306d, topicName=原发性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8e4c53, createdName=jiyangfei, createdTime=Sun May 15 22:10:00 CST 2016, time=2016-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=100610, encodeId=aba2100610de, content=谢谢分享。, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/X5rIibvOT8wIavvRus9ic9ykU2O4icURoYHRZ8GiakmmpTvlumLDRFJCXeUicOeeLAsiaqwWpqYCdsLXeibBv7s48aACA/132, createdBy=509a1938333, createdName=akira明, createdTime=Fri Aug 19 00:22:00 CST 2016, time=2016-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1980770, encodeId=c2461980e70c6, content=<a href='/topic/show?id=3c8662445ce' target=_blank style='color:#2F92EE;'>#梅毒感染#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62445, encryptionId=3c8662445ce, topicName=梅毒感染)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=zhangpaul93, createdTime=Sat Feb 13 19:10:00 CST 2016, time=2016-02-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71014, encodeId=5452e10148d, content=感谢分享。, beContent=null, objectType=article, channel=null, level=null, likeNumber=138, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=73801651090, createdName=1ddc978cm67(暂无匿称), createdTime=Fri Mar 18 00:09:00 CST 2016, time=2016-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1952650, encodeId=9a37195265026, content=<a href='/topic/show?id=a37ce8961a1' target=_blank style='color:#2F92EE;'>#继发性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78961, encryptionId=a37ce8961a1, topicName=继发性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2317301, createdName=xzw113, createdTime=Fri Nov 04 05:10:00 CST 2016, time=2016-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=63703, encodeId=5e3563e038f, content=头一次听说, beContent=null, objectType=article, channel=null, level=null, likeNumber=135, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160613/IMG575D9886B86721544.jpg, createdBy=07961686486, createdName=1de4921fm57(暂无匿称), createdTime=Mon Feb 08 13:57:00 CST 2016, time=2016-02-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1467115, encodeId=f999146e11519, content=<a href='/topic/show?id=ef32e9539e8' target=_blank style='color:#2F92EE;'>#罕见#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79539, encryptionId=ef32e9539e8, topicName=罕见)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=29f36868190, createdName=syscxl, createdTime=Wed Feb 03 02:10:00 CST 2016, time=2016-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=62732, encodeId=5a3962e328a, content=少见, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuK9CDibOwszLoEBg36ZXqzB5NDasNV9GTfFDmBicM1V8hUS4OtTicG3IiaFIKq4wqD23LUxORRJXqjVs/0, createdBy=00e81647535, createdName=I come, createdTime=Tue Feb 02 06:52:00 CST 2016, time=2016-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=62606, encodeId=98886260600, content=值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Mon Feb 01 22:28:00 CST 2016, time=2016-02-01, status=1, ipAttribution=)]
    2016-02-03 syscxl
  9. [GetPortalCommentsPageByObjectIdResponse(id=1724425, encodeId=11911e2442533, content=<a href='/topic/show?id=78ece8958b2' target=_blank style='color:#2F92EE;'>#继发#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78958, encryptionId=78ece8958b2, topicName=继发)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=499d33645837, createdName=feifers, createdTime=Tue Feb 09 06:10:00 CST 2016, time=2016-02-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1846483, encodeId=9b0e184648361, content=<a href='/topic/show?id=d3a33e0306d' target=_blank style='color:#2F92EE;'>#原发性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37030, encryptionId=d3a33e0306d, topicName=原发性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8e4c53, createdName=jiyangfei, createdTime=Sun May 15 22:10:00 CST 2016, time=2016-05-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=100610, encodeId=aba2100610de, content=谢谢分享。, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/X5rIibvOT8wIavvRus9ic9ykU2O4icURoYHRZ8GiakmmpTvlumLDRFJCXeUicOeeLAsiaqwWpqYCdsLXeibBv7s48aACA/132, createdBy=509a1938333, createdName=akira明, createdTime=Fri Aug 19 00:22:00 CST 2016, time=2016-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1980770, encodeId=c2461980e70c6, content=<a href='/topic/show?id=3c8662445ce' target=_blank style='color:#2F92EE;'>#梅毒感染#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62445, encryptionId=3c8662445ce, topicName=梅毒感染)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=zhangpaul93, createdTime=Sat Feb 13 19:10:00 CST 2016, time=2016-02-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71014, encodeId=5452e10148d, content=感谢分享。, beContent=null, objectType=article, channel=null, level=null, likeNumber=138, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=73801651090, createdName=1ddc978cm67(暂无匿称), createdTime=Fri Mar 18 00:09:00 CST 2016, time=2016-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1952650, encodeId=9a37195265026, content=<a href='/topic/show?id=a37ce8961a1' target=_blank style='color:#2F92EE;'>#继发性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78961, encryptionId=a37ce8961a1, topicName=继发性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2317301, createdName=xzw113, createdTime=Fri Nov 04 05:10:00 CST 2016, time=2016-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=63703, encodeId=5e3563e038f, content=头一次听说, beContent=null, objectType=article, channel=null, level=null, likeNumber=135, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160613/IMG575D9886B86721544.jpg, createdBy=07961686486, createdName=1de4921fm57(暂无匿称), createdTime=Mon Feb 08 13:57:00 CST 2016, time=2016-02-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1467115, encodeId=f999146e11519, content=<a href='/topic/show?id=ef32e9539e8' target=_blank style='color:#2F92EE;'>#罕见#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79539, encryptionId=ef32e9539e8, topicName=罕见)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=29f36868190, createdName=syscxl, createdTime=Wed Feb 03 02:10:00 CST 2016, time=2016-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=62732, encodeId=5a3962e328a, content=少见, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuK9CDibOwszLoEBg36ZXqzB5NDasNV9GTfFDmBicM1V8hUS4OtTicG3IiaFIKq4wqD23LUxORRJXqjVs/0, createdBy=00e81647535, createdName=I come, createdTime=Tue Feb 02 06:52:00 CST 2016, time=2016-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=62606, encodeId=98886260600, content=值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Mon Feb 01 22:28:00 CST 2016, time=2016-02-01, status=1, ipAttribution=)]
    2016-02-02 I come

    少见

    0

  10. 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Mon Feb 01 22:28:00 CST 2016, time=2016-02-01, status=1, ipAttribution=)]
    2016-02-01 dhzzm

    值得学习

    0

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