ARCH PATHOL LAB MED:通过磁共振成像检测前列腺癌?

2019-02-05 MedSci MedSci原创

在格里森评分(GS7前列腺癌中,格里森模式4GP4)的数量是一个重要的预后因素,并影响治疗决策。目前,磁共振成像(MRI)靶向活检已越来越多地用于临床实践。

研究目的是探讨MRI靶向活检是否可以检测GP 7前列腺癌的GP 4量,以及是否改善活检/根治性前列腺切除术GS一致性。

共有243名患者进行了成对标准和MRI靶向活检,其中65名患者接受了根治性前列腺切除术。活检结果,包括GS和肿瘤体积,与根治性前列腺切除术的发现相关。

结果显示,通过MRI靶向活组织检查检测到的较多前列腺癌为GS 7或更高。通过MRI靶向活检,GS 7癌症的平均GP 4百分比为31.0%±29.3%,而标准活组织检查为25.1%±29.5%。分别通过靶向活检和标准活检诊断218例(56.0%)和217例(44.2%)前列腺癌中共有122GP 410%或更高(P = .01)。格列森升级见于来自MRI靶向活检的59例(20.3%)中的12例和来自标准活检的57例(42.1%)中的24例(P = .01)。在标准活检中,格里森升级与活检癌症体积相反,GP 430%或更低。在MRI靶向活组织检查中未发现这种相关性。

研究表明,核磁共振成像靶向活检可以检测出更具侵袭性的前列腺癌,并降低根治性前列腺切除术中格里森升级的风险。该研究支持MRI靶向活组织检查在前列腺癌检查中的潜在作用,并在前列腺活检报告中包含GP 4的百分比。

原始出处:

Yani Zhao, Fang-Ming Deng, Hongying Huang, Prostate Cancers Detected by Magnetic Resonance Imaging–Targeted Biopsies Have a Higher Percentage of Gleason Pattern 4 Component and Are Less Likely to Be Upgraded in Radical Prostatectomies

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    2019-08-08 yb6560
  2. [GetPortalCommentsPageByObjectIdResponse(id=1786252, encodeId=713a1e8625228, content=<a href='/topic/show?id=569f13e9045' target=_blank style='color:#2F92EE;'>#Pathol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13790, encryptionId=569f13e9045, topicName=Pathol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4b65161, createdName=yb6560, createdTime=Thu Aug 08 23:15:00 CST 2019, time=2019-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=361795, encodeId=580b361e9527, content=了解一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOgo3iaicb1Imgk1yIfnvr6oXzibcAFB6puAyNJXbzWhNuLqaFYBVRWjh7rghkvFLPxMAfD5ib3nXwVD/0, createdBy=bed21972958, createdName=wxl882001, createdTime=Fri Mar 01 21:17:12 CST 2019, time=2019-03-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=360133, encodeId=69c8360133a2, content=了解一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOgo3iaicb1Imgk1yIfnvr6oXzibcAFB6puAyNJXbzWhNuLqaFYBVRWjh7rghkvFLPxMAfD5ib3nXwVD/0, createdBy=bed21972958, createdName=wxl882001, createdTime=Thu Feb 07 14:52:25 CST 2019, time=2019-02-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1341651, encodeId=7e2313416517c, content=<a href='/topic/show?id=24b8e37529a' target=_blank style='color:#2F92EE;'>#磁共振#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73752, encryptionId=24b8e37529a, topicName=磁共振)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=24a22500182, createdName=1696533704_45270454, createdTime=Wed Feb 06 15:15:00 CST 2019, time=2019-02-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1609549, encodeId=8767160954983, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Wed Feb 06 15:15:00 CST 2019, time=2019-02-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=359969, encodeId=4e7435996945, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Tue Feb 05 07:48:34 CST 2019, time=2019-02-05, status=1, ipAttribution=)]
    2019-03-01 wxl882001

    了解一下

    0

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    2019-02-07 wxl882001

    了解一下

    0

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    2019-02-06 仁医06
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    2019-02-05 龙胆草

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