J Neurol Neurosur Ps:脑外伤患者精神药物和止痛药使用情况分析

2021-02-14 MedSci原创 MedSci原创

颅脑损伤后使用精神药物和止痛药物的比例较高,建议定期进行医学随访并总结这些药物使用情况。

近日,神经病学领域权威取杂志Journal Of Neurology Neurosurgery And Psychiatry上发表了一篇研究文章,该研究旨在通过以人群为基础的创伤性脑损伤患者队列评估精神药物和止痛药物的使用情况,并与来自相似背景的对照者进行比较。

研究人员评估了在2006年至2012年期间在医院或专科门诊诊断为脑外伤的患者数据。没有被诊断为脑外伤的同胞作为对照者。研究人员评估了在创伤性脑损伤前后12个月内精神药物和止痛药的使用情况。

研究人员确定了23425名脑外伤患者和199658名未受影响的对照者。在创伤性脑损伤患者队列中,36.6%的患者在创伤性脑损伤发生前的12个月内至少服用过一种精神药物或止痛药。脑损伤12个月后,用药率增至45.0%,绝对增幅为8.4% (p<0.001)。脑外伤后阿片类药物(从16.3%增加到21.6%,p<0.001)和非阿片类镇痛药物(从20.3%增加到26.6%,p<0.001)使用率增加最多。大多数处方为短期处方;阿片类处方占20.6%,苯二氮卓类处方超过6个月的占37.3%。与对照者相比,脑外伤患者在外伤前(OR: 1.62, 95%CI: 1.59-1.65)和外伤后(OR: 2.30, 95%CI: 2.26-2.34)服用任何精神药物或止痛药物的几率增加。

由此可见,颅脑损伤后使用精神药物和止痛药物的比例较高,建议定期进行医学随访并总结这些药物使用情况

原始出处:

Yasmina Molero.et al.Psychotropic and pain medication use in individuals with traumatic brain injury—a Swedish total population cohort study of 240 000 persons.Journal Of Neurology Neurosurgery And Psychiatry.2021.https://jnnp.bmj.com/content/early/2021/02/08/jnnp-2020-324353

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    2021-02-24 yinhl1978
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    2021-02-25 三生有幸9135

    建议定期进行医学随访总

    0

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    2021-02-16 lsndxfj
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    2021-02-16 zhangxingru
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    2021-02-15 carrotlyl

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