JACC:Heart Failure:哮喘患者更易罹患心血管疾病

2017-06-28 tulip1999 来宝网

一项最新研究首次发现了哮喘病史与左心室肥厚发生率增加有关,而后者是心力衰竭的一个危险因素。



哮喘病史与心力衰竭的危险因素有关】一项最新研究首次发现了哮喘病史与左心室肥厚发生率增加有关,而后者是心力衰竭的一个危险因素

据估计,在美国每有12人当中大约就有1人(约2,500万人)患有哮喘,而且这个数字还在不断增加。

之前已有研究表明,哮喘与心血管疾病的风险增加有关,包括心脏病发作、心脏病和中风。

现在,发表在《JACC:心力衰竭》杂志上的这项最新研究表明:有哮喘病史的人将面临着更大的左心室肥厚(LVH)风险

左心室肥厚(LVH)是一种以左心室增厚和扩大为特征的疾病。左心室是负责泵出富氧血液将其输送至全身的一个心腔。

许多左心室肥厚(LVH)患者没有任何症状或体征,特别是在早期阶段。当出现症状时,可能包括气短、胸痛、疲劳、心悸、头晕或昏厥。

高血压是左心室肥厚(LVH)最常见的原因,尽管左心室肥厚(LVH)也可能是由于主动脉瓣狭窄和其他使心脏缩窄的原因所致。

与哮喘病史有关的左心室质量指数(LVMI)

在这项最新研究中,资深作者,洛杉矶新奥尔良杜兰大学肥胖研究中心的Lu Qi博士及其同事对参与Bogalusa心脏研究的1,118名健康成人的健康数据进行了评估。

所有成人均完成了一份详细的儿童哮喘病史调查表。对所有研究对象进行为期10年左右的随访。

在随访过程中两到四个时间点,用超声心动图对参与者左室质量(LVM)——左心室的尺寸进行评估。研究人员依据参与者的身高尺寸对左室质量(LVM)进行了相应的调整,得出了他们的左心室质量指数(LVMI)。

与没有哮喘史的成年人相比,那些的确存在这种呼吸道疾病病史的成年人被发现具有较高的调整后的平均左室质量(LVM),即更高的左心室质量指数(LVMI)。

据研究小组报告,在收缩压较高的参与者,哮喘病史与左室质量(LVM)及左心室质量指数(LVMI)更高之间的联系更为密切。

在将心血管疾病(CVD)的其他关键危险因素,包括年龄、吸烟状况、心率和血压药物使用在内都考虑进去之后,该研究结果仍然成立。

在谈到该研究结果的意义时,研究人员说道:

“我们的研究数据表明,有哮喘病史的人改变积极的生活方式甚至是进行药物治疗,尤其是那些高血压病患者,可降低其罹患心血管疾病的风险。”

“还需要在其他人群中进行进一步的研究对我们的研究结果加以验证,”研究小组补充说道。

原始出处:

Dianjianyi Sun, Tiange Wang, Yoriko Heianza, et al. A History of Asthma From Childhood and Left Ventricular Mass in Asymptomatic Young Adults : The Bogalusa Heart Study. JACC: Heart Failure, 2017.https://doi.org/10.1016/j.jchf.2017.03.009.

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    2017-12-28 hbwxf
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    2017-08-15 docwu2019
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    2017-06-30 zhaojie88
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    2017-06-30 slcumt
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    2017-06-28 dhzzm

    学习了分享了

    0

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    2017-06-28 有备才能无患

    有哮喘病史的人改变积极的生活方式甚至是进行药物治疗,尤其是那些高血压病患者,可降低其罹患心血管疾病的风险。”

    0

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