J Int Med Res:顺式阿曲库铵对麻醉诱导期间喉罩置入患者校正QT间期延长的影响

2018-08-12 李华宇 罂粟花

本研究目的是观察麻醉诱导期间喉罩置入患者校正QT(QTc)间期延长的发生率及顺式阿曲库铵对QTc间期的影响。

背景与目的:本研究目的是观察麻醉诱导期间喉罩置入患者校正QT(QTc)间期延长的发生率及顺式阿曲库铵对QTc间期的影响。

方法:将88名患者分为两组:顺式阿曲库铵组(n = 45)和非顺式阿曲库铵组(n = 43)。通过12导联动态心电图连续记录患者从病房到麻醉诱导后的QTc间期。

结果:在顺式阿曲库铵组中,患者到达手术室后QTc间期从417.9±27.9ms显着增加到451.6±32.5ms,且在休息15min后显着降低至432.4±32.5ms; 给予异丙酚和芬太尼之后再次显着增加到459.7±23.8毫秒。然而,顺式阿曲库铵注射后QTc间期缩短。在非顺式阿曲库铵组中,QTc间期在给予芬太尼和异丙酚之前与顺式阿曲库铵组相似的变化。

结论:当患者到达手术室即刻和给予异丙酚和芬太尼后,QTc间期显着延长。顺式阿曲库铵对喉罩置入患者的QTc间期没有影响。

原始出处

Xuan C, Wu N, Li Y, et al. Corrected QT interval prolongation during anesthetic induction for laryngeal mask airway insertion with or without cisatracurium. J Int Med Res. 2018 May;46(5):1990-2000. doi: 10.1177/0300060518764185.

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    2018-08-14 xinmeili
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  6. [GetPortalCommentsPageByObjectIdResponse(id=1705573, encodeId=08b41e0557382, content=<a href='/topic/show?id=8c77103094c3' target=_blank style='color:#2F92EE;'>#麻醉诱导期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103094, encryptionId=8c77103094c3, topicName=麻醉诱导期)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=dc9630990780, createdName=mxj1971622, createdTime=Wed Mar 27 04:08:00 CST 2019, time=2019-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1796525, encodeId=65761e965254b, content=<a href='/topic/show?id=511f18046c2' target=_blank style='color:#2F92EE;'>#T间期延长#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=18046, encryptionId=511f18046c2, topicName=T间期延长)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9d0b2500136, createdName=12498b08m90暂无昵称, createdTime=Fri Jul 05 18:08:00 CST 2019, time=2019-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1677836, encodeId=30f116e7836e8, content=<a href='/topic/show?id=2ba6150049b' target=_blank style='color:#2F92EE;'>#QT间期延长#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15004, encryptionId=2ba6150049b, topicName=QT间期延长)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3d0327606456, createdName=ewsr10, createdTime=Mon Jan 21 01:08:00 CST 2019, time=2019-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1399456, encodeId=6ca81399456a0, content=<a href='/topic/show?id=72d615003a5' target=_blank style='color:#2F92EE;'>#QT间期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15003, encryptionId=72d615003a5, topicName=QT间期)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d8202208740, createdName=xinmeili, createdTime=Tue Aug 14 10:08:00 CST 2018, time=2018-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1609054, encodeId=f913160905468, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Tue Aug 14 10:08:00 CST 2018, time=2018-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=338185, encodeId=cac2338185e5, content=了解一下,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Sun Aug 12 19:34:22 CST 2018, time=2018-08-12, status=1, ipAttribution=)]
    2018-08-12 天地飞扬

    了解一下,谢谢分享!

    0