Stroke:洛杉矶运动量表(LAMS)对急性脑缺血的效用评估!

2018-02-23 MedSci MedSci原创

目前,因为大血管闭塞(LVO)可直接进入综合性中风中心(CSC),因此,已经开发了院前指数来识别急性脑缺血(ACI)患者,但很少有研究在院前环节进行验证,且其对颅内出血患者的作用尚未确定。近期,一项发表在杂志Stroke上的研究旨在验证洛杉矶运动量表(LAMS)对适合LVO和CSC患者(LVO ACI和颅内出血患者)的识别,并将LAMS与其他量表进行了比较。LAMS由救护人员对接受救护车前往医院的

目前,因为大血管闭塞(LVO)可直接进入综合性中风中心(CSC),因此,已经开发了院前指数来识别急性脑缺血(ACI)患者,但很少有研究在院前环节进行验证,且其对颅内出血患者的作用尚未确定。

近期,一项发表在杂志Stroke上的研究旨在验证洛杉矶运动量表(LAMS)对适合LVO和CSC患者(LVO ACI和颅内出血患者)的识别,并将LAMS与其他量表进行了比较。

LAMS由救护人员对接受救护车前往医院的患者进行评估,以确定(1)所有ACI患者的LVO和(2)所有可疑中风患者中CSC适宜的患者。此外,LAMS同时与其他6个建议的辅助用药和全国卫生研究院卒中量表进行比较。

最终,在94名患者中,平均年龄为70(±13)岁,女性为49%。有76%的患者诊断为ACI(由于48%的LVO和28%的非LVO),19%的颅内出血和5%的神经血管病变。在所有疑似卒中患者中,救护人员使用LOA对LVO中的ACI患者(C统计量,0.79;准确率,0.72)和适宜CSC者(C统计量,0.80;准确度,0.72)有中度良好的识别能力。如果在急诊后期进行,与7个量表相比,LAMS对于ACI中的LVO(精确度LAMS,0.70;其他量表,0.62-0.68)和适宜CSC者的效用具有可比性,且准确性更高(精确度LAMS,0.73;其他比例,0.56-0.73)。

此项研究结果表明:救护人员在现场进行的LAMS可准确识别适合LVO和CSC的患者。LAMS的表现与更广泛的院前和全国卫生研究院卒中量表相当或更好。

原始出处:
Noorian AR, Sanossian N, et al. Los Angeles Motor Scale to Identify Large Vessel Occlusion: Prehospital Validation and Comparison With Other Screens. Stroke. 2018 Feb 19. pii: STROKEAHA.117.019228. doi: 10.1161/STROKEAHA.117.019228. 

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    2018-09-19 lxg951
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    2018-07-31 xuyu
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