JACC:TAVR后需要晚期(≥48h)永久起搏器的高度传导障碍预测因子

2018-08-07 xiangting MedSci原创

该分析显示在这个队列中,基线右束支传导阻滞和TAVR后PR长度增加数量是TAVR后需要进行PPM置换的晚期(≥48h)高度传导障碍独立预测因子。

这项研究旨在确定经导管主动脉瓣置换术(TAVR)后需要晚期(≥48h)永久起搏器置换(PPM)的高度传导障碍的预测因子。

研究人员通过回顾性分析意大利米兰单个中心2007年10月至2015年7月的TAVR数据库,确定了连续性患者数据。将delta PR(ΔPR)和delta QRS(ΔQRS)间隔定义为TAVR后48小时最后一个PR和QRS长度与基线PR和QRS长度的差值。

总人群包括740名患者。排除了78名已经有PPM的患者和51名TAVR后PPM<48小时患者。最终分析包括611名患者。54名患者(8.8%)出现了高度传导障碍,需要TAVR后PPM≥48小时。需要晚期PPM植入的患者QRS较宽(113±25ms vs.105±23ms;p=0.009)、基线右束支传导阻滞发生率较高(12.9%vs.5.3%;p=0.026),并且植入的自扩张瓣膜更多(51.8%vs.31.9%;p=0.003)。ΔPR为40±51ms(p=0.0001),ΔQRS为22±61ms(p=0.001)。多因素分析显示,基线右束支传导阻滞(比值比:3.56;95%置信区间:1.07至11.77;p=0.037)和ΔPR(每增加10ms优势比为:1.31;95%置信区间:1.18至1.45;p=0.0001)是延迟性高度传导障碍的独立预测因子。

该分析显示在这个队列中,基线右束支传导阻滞和TAVR后PR长度增加数量是TAVR后需要进行PPM置换的晚期(≥48h)高度传导障碍独立预测因子。简单的心电图分析有助于检测到TAVR 48小时以后可能发生的潜在致命高度传导障碍。

原始出处:

本文系梅斯医学(MedSci)原创译整理,转载需授权!

评论区 (6)
#插入话题
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    2018-09-27 wangtianj2007@

    #AVR#

    0

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    2018-12-31 hbwxf

    #JACC#

    0

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    2018-08-09 宋威
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    2018-08-09 HNYYM
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    2018-08-09 12498568m50暂无昵称

    #ACC#

    0

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    2018-08-07 清风拂面

    谢谢分享学习

    0

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