JAHA:术前右心室游离壁纵向应变可作为严重三尖瓣关闭不全术后的预后指标

2021-04-18 MedSci原创 MedSci原创

术前RVFWSL作为RV功能障碍的指标是接受重度功能性TR手术患者的独立预后指标。因此,术前RVFWSL可以帮助判断严重功能性TR患者的最佳手术时机。

在发生不可逆的右心室(RV)功能障碍之前,应对严重的三尖瓣关闭不全(TR)进行干预。但是,当前的指南并未提供与RV收缩功能相关的标准来指导最佳手术时机。

近日,血管疾病领域权威杂志JAHA上发表了一篇研究文章,研究人员纳入了115例连续就诊的患者(年龄为62±10岁;男性占23.5%;62.6%[n=72]的患者先前接受过左侧瓣膜手术),他们在两个三级中心接受了重度功能性TR手术。

研究人员收集了患者术前的临床和超声心动图参数,包括RV游离壁纵向应变(RVFWSL)。该研究的主要终点是心脏死亡和手术后5年归因于心血管原因的计划外再入院的综合结局。

在333人次每年的随访期间,有40例患者(34.8%)出现了主要终点。由于心血管原因,有11例患者发生心源性死亡和34例患者出现计划外再入院治疗,其中5例两种情况均经历过。术前绝对RVFWSL<24%与主要终点相关(风险比为2.30;95%CI为1.22-4.36;P=0.011),与临床风险因素无关,包括欧洲心脏手术风险评估系统II和血红蛋白水平。同时,RV收缩功能的其他常规超声心动图指标并不显著。将RVFWSL绝对值<24%添加到临床模型增加了其对主要终点的预测价值。

由此可见,术前RVFWSL作为RV功能障碍的指标是接受重度功能性TR手术患者的独立预后指标。因此,术前RVFWSL可以帮助判断严重功能性TR患者的最佳手术时机。

原始出处:

Minkwan Kim.et al.Preoperative Right Ventricular Free‐Wall Longitudinal Strain as a Prognosticator in Isolated Surgery for Severe Functional Tricuspid Regurgitation.J AM HEART ASSOC.2021.https://www.ahajournals.org/doi/10.1161/JAHA.120.019856

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1268497, encodeId=4a87126849e16, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Tue Apr 20 07:06:20 CST 2021, time=2021-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1374193, encodeId=ab1013e41935e, content=<a href='/topic/show?id=8de610018644' target=_blank style='color:#2F92EE;'>#预后指标#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100186, encryptionId=8de610018644, topicName=预后指标)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ca3c375, createdName=jwf_2001, createdTime=Tue Apr 20 07:06:20 CST 2021, time=2021-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1543784, encodeId=1fd61543e840d, content=<a href='/topic/show?id=52d93862e06' target=_blank style='color:#2F92EE;'>#右心室#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38627, encryptionId=52d93862e06, topicName=右心室)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f18d13610637, createdName=124988c7m99暂无昵称, createdTime=Tue Apr 20 07:06:20 CST 2021, time=2021-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1578486, encodeId=b0c015e8486c0, content=<a href='/topic/show?id=a1021962883' target=_blank style='color:#2F92EE;'>#三尖瓣#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=19628, encryptionId=a1021962883, topicName=三尖瓣)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c7cb16409801, createdName=124985dbm11(暂无昵称), createdTime=Tue Apr 20 07:06:20 CST 2021, time=2021-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=958040, encodeId=2717958040e2, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210414/74acf51dc67c4905b857b73fdb80f145/1204a71866c844d49799244c743c6cf5.jpg, createdBy=47ee5419152, createdName=ms4000000651155070, createdTime=Sun Apr 18 16:41:52 CST 2021, time=2021-04-18, status=1, ipAttribution=)]
    2021-04-20 zhaohui6731
  2. [GetPortalCommentsPageByObjectIdResponse(id=1268497, encodeId=4a87126849e16, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Tue Apr 20 07:06:20 CST 2021, time=2021-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1374193, encodeId=ab1013e41935e, content=<a href='/topic/show?id=8de610018644' target=_blank style='color:#2F92EE;'>#预后指标#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100186, encryptionId=8de610018644, topicName=预后指标)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ca3c375, createdName=jwf_2001, createdTime=Tue Apr 20 07:06:20 CST 2021, time=2021-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1543784, encodeId=1fd61543e840d, content=<a href='/topic/show?id=52d93862e06' target=_blank style='color:#2F92EE;'>#右心室#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38627, encryptionId=52d93862e06, topicName=右心室)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f18d13610637, createdName=124988c7m99暂无昵称, createdTime=Tue Apr 20 07:06:20 CST 2021, time=2021-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1578486, encodeId=b0c015e8486c0, content=<a href='/topic/show?id=a1021962883' target=_blank style='color:#2F92EE;'>#三尖瓣#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=19628, encryptionId=a1021962883, topicName=三尖瓣)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c7cb16409801, createdName=124985dbm11(暂无昵称), createdTime=Tue Apr 20 07:06:20 CST 2021, time=2021-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=958040, encodeId=2717958040e2, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210414/74acf51dc67c4905b857b73fdb80f145/1204a71866c844d49799244c743c6cf5.jpg, createdBy=47ee5419152, createdName=ms4000000651155070, createdTime=Sun Apr 18 16:41:52 CST 2021, time=2021-04-18, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1268497, encodeId=4a87126849e16, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Tue Apr 20 07:06:20 CST 2021, time=2021-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1374193, encodeId=ab1013e41935e, content=<a href='/topic/show?id=8de610018644' target=_blank style='color:#2F92EE;'>#预后指标#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100186, encryptionId=8de610018644, topicName=预后指标)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ca3c375, createdName=jwf_2001, createdTime=Tue Apr 20 07:06:20 CST 2021, time=2021-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1543784, encodeId=1fd61543e840d, content=<a href='/topic/show?id=52d93862e06' target=_blank style='color:#2F92EE;'>#右心室#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38627, encryptionId=52d93862e06, topicName=右心室)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f18d13610637, createdName=124988c7m99暂无昵称, createdTime=Tue Apr 20 07:06:20 CST 2021, time=2021-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1578486, encodeId=b0c015e8486c0, content=<a href='/topic/show?id=a1021962883' target=_blank style='color:#2F92EE;'>#三尖瓣#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=19628, encryptionId=a1021962883, topicName=三尖瓣)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c7cb16409801, createdName=124985dbm11(暂无昵称), createdTime=Tue Apr 20 07:06:20 CST 2021, time=2021-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=958040, encodeId=2717958040e2, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210414/74acf51dc67c4905b857b73fdb80f145/1204a71866c844d49799244c743c6cf5.jpg, createdBy=47ee5419152, createdName=ms4000000651155070, createdTime=Sun Apr 18 16:41:52 CST 2021, time=2021-04-18, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1268497, encodeId=4a87126849e16, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Tue Apr 20 07:06:20 CST 2021, time=2021-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1374193, encodeId=ab1013e41935e, content=<a href='/topic/show?id=8de610018644' target=_blank style='color:#2F92EE;'>#预后指标#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100186, encryptionId=8de610018644, topicName=预后指标)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ca3c375, createdName=jwf_2001, createdTime=Tue Apr 20 07:06:20 CST 2021, time=2021-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1543784, encodeId=1fd61543e840d, content=<a href='/topic/show?id=52d93862e06' target=_blank style='color:#2F92EE;'>#右心室#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38627, encryptionId=52d93862e06, topicName=右心室)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f18d13610637, createdName=124988c7m99暂无昵称, createdTime=Tue Apr 20 07:06:20 CST 2021, time=2021-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1578486, encodeId=b0c015e8486c0, content=<a href='/topic/show?id=a1021962883' target=_blank style='color:#2F92EE;'>#三尖瓣#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=19628, encryptionId=a1021962883, topicName=三尖瓣)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c7cb16409801, createdName=124985dbm11(暂无昵称), createdTime=Tue Apr 20 07:06:20 CST 2021, time=2021-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=958040, encodeId=2717958040e2, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210414/74acf51dc67c4905b857b73fdb80f145/1204a71866c844d49799244c743c6cf5.jpg, createdBy=47ee5419152, createdName=ms4000000651155070, createdTime=Sun Apr 18 16:41:52 CST 2021, time=2021-04-18, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1268497, encodeId=4a87126849e16, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Tue Apr 20 07:06:20 CST 2021, time=2021-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1374193, encodeId=ab1013e41935e, content=<a href='/topic/show?id=8de610018644' target=_blank style='color:#2F92EE;'>#预后指标#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100186, encryptionId=8de610018644, topicName=预后指标)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ca3c375, createdName=jwf_2001, createdTime=Tue Apr 20 07:06:20 CST 2021, time=2021-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1543784, encodeId=1fd61543e840d, content=<a href='/topic/show?id=52d93862e06' target=_blank style='color:#2F92EE;'>#右心室#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38627, encryptionId=52d93862e06, topicName=右心室)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f18d13610637, createdName=124988c7m99暂无昵称, createdTime=Tue Apr 20 07:06:20 CST 2021, time=2021-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1578486, encodeId=b0c015e8486c0, content=<a href='/topic/show?id=a1021962883' target=_blank style='color:#2F92EE;'>#三尖瓣#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=19628, encryptionId=a1021962883, topicName=三尖瓣)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c7cb16409801, createdName=124985dbm11(暂无昵称), createdTime=Tue Apr 20 07:06:20 CST 2021, time=2021-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=958040, encodeId=2717958040e2, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210414/74acf51dc67c4905b857b73fdb80f145/1204a71866c844d49799244c743c6cf5.jpg, createdBy=47ee5419152, createdName=ms4000000651155070, createdTime=Sun Apr 18 16:41:52 CST 2021, time=2021-04-18, status=1, ipAttribution=)]
    2021-04-18 ms4000000651155070

    学习了

    0

相关资讯

Circ-Cardiovasc Inte:经导管主动脉瓣置换术患者的临床结局及预后指标!

由此可见,TAVR是早期肝脏疾病患者重度主动脉瓣狭窄可行的治疗或是肝病根治前的过渡治疗。Child-Pugh B-C级患者、尤其是合并肾损害的患者,具有非常低的存活率,以及TAVR应慎重考虑以避免无效治疗。这些结果可能有助于改善肝病患者的临床决策过程和管理。

Crit Care:SOFA评分的早期变化可作为败血症患者28天死亡率的预后指标

由此可见,ΔSOFA是28天死亡率有效地早期预测标志物,可以作为未来败血症试验的终点。

Nat Commun:恶性胸膜间皮瘤的克隆结构可作为预后指标并影响肿瘤微环境

恶性胸膜间皮瘤(MPM)是一种罕见的、无法治愈的癌症。

Clinica Chimica Acta:血浆骨桥蛋白是急性脑出血患者的预后指标?

骨桥蛋白(Osteopontin, OPN)是一种母体细胞蛋白,在急性脑损伤后的脑组织中可大量产生。本研究在一项临床研究中确定了急性脑出血(ICH)患者血浆OPN浓度与预后的关系。 在这个前瞻性观察研究中,研究人员招募了162例ICH患者和162名健康对照者,使用国立卫生研究院卒中量表(NIHSS)评分和血肿量评估了出血严重程度,不良预后定义为卒中后90天的改良Rankin量表≥2,而早期神

Br J Cancer:无肿瘤距离(TFD):早期宫颈癌患者的新预后指标

早期宫颈癌的预后标志物可用于调整患者的手术类型,包括淋巴结分期、子宫旁切除术的类型以及最重要的辅助治疗的应用。既往的大多数研究的主要局限性在于,研究期间两种临床治疗方法特别是评估单个标记的方法的标准化

Stroke:入院中性粒细胞与淋巴细胞比率可作为大血管闭塞卒中结局的预后指标

由此可见,较高的入院NLR是机械性血栓切除术治疗的大血管闭塞患者症状性颅内出血和3个月死亡率的独立预测因子,其可以用于确定需要辅助抗炎治疗的目标人群。