INFLAMM BOWEL DIS:中国儿童炎症性肠病报告

2013-03-01 张旦昕 陈静 中新网

  上海瑞金医院儿科主任许春娣领衔的课题组首次调研了10年来上海儿童中炎症性肠病的发病情况,完成了国际上首个关于中国儿童中炎症性肠病地区性多中心大样本的临床研究报告。   业内专家指出,该研究报告问世将对中国儿童炎症性肠病的诊断和防治起到积极的促进和推动作用,并对建立中国儿童炎症性肠病的诊疗指南提供了理论基础。   炎症性肠病是一组病因不明的慢性肠道炎症,主要包括溃疡性结肠炎和克罗

  上海瑞金医院儿科主任许春娣领衔的课题组首次调研了10年来上海儿童中炎症性肠病的发病情况,完成了国际上首个关于中国儿童中炎症性肠病地区性多中心大样本的临床研究报告。

  业内专家指出,该研究报告问世将对中国儿童炎症性肠病的诊断和防治起到积极的促进和推动作用,并对建立中国儿童炎症性肠病的诊疗指南提供了理论基础。

  炎症性肠病是一组病因不明的慢性肠道炎症,主要包括溃疡性结肠炎和克罗恩病等。其临床表现主要包括腹泻、血便和腹痛等消化道症状。研究资料显示,炎症性肠病目前尚无根治手段,且其发生肠癌等肿瘤的风险数倍高于正常人,由此严重影响了患者的身体健康和生活质量。以往西方国家的炎症性肠病患病率较高,在我国发病率较低。

  许春娣介绍,近年发现,炎症性肠病在中国的发病率也呈逐年上升趋势,正成为中国人群中多发的消化疾病之一。炎症性肠病也多见于儿童,然而在中国却缺乏有关儿童患者的临床研究资料。

  据了解,课题组首次联合了上海4所儿童医院的消化科,对近10年来上海儿童炎症性肠病的发病情况进行了较全面的研究和调查。研究结果显示,2000-2010年间上海地区0-14岁炎症性肠病新发人数占申城同年龄段常驻人口的比例逐年上升,发病率从2001年的0.5/100万上升到了2011年的6.1/100万。

  该项研究为儿童炎症性肠病的多中心临床研究建立了良好的基础。许春娣表示,课题组将继续致力于对该疾病治疗及转归的观察和研究,并针对该疾病的病因及发病机制作进一步探讨。

  据知,国际消化领域权威杂志《炎性肠疾病》(Inflammatory Bowel Diseases,IF:4.9)在线发表了许春娣课题组的研究成果。



    

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    2013-03-31 lxg951
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    2014-02-08 yuandd
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    2013-03-03 xiaoyeshuang
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