科学家研发用于治疗年龄相关性黄斑变性的眼药水&#160有望取代注射治疗

2017-05-17 cnBeta cnBeta

年龄相关性黄斑变性 (AMD) 是一种导致老年人致盲的常见疾病,是一种可引起视力迅速丧失的视网膜退行性病变。患者每月需要用注射液进行治疗。 据外媒报道,现在伯明翰大学的科学家团队开发了一种突破性的新治疗方法,用简单的眼药水可取代此前的注射液。据悉,仅在英国,AMD 就影响了超过 60 万人。而在美国,这种疾病是 50 岁以上人群失明的最常见原因之一。目前的治疗包括直接将药物注射至眼球内。这



年龄相关性黄斑变性 (AMD) 是一种导致老年人致盲的常见疾病,是一种可引起视力迅速丧失的视网膜退行性病变。患者每月需要用注射液进行治疗。 据外媒报道,现在伯明翰大学的科学家团队开发了一种突破性的新治疗方法,用简单的眼药水可取代此前的注射液。

据悉,仅在英国,AMD 就影响了超过 60 万人。而在美国,这种疾病是 50 岁以上人群失明的最常见原因之一。目前的治疗包括直接将药物注射至眼球内。这些注射不仅有损伤眼睛的危险,还令患者非常痛苦。

值得庆幸的是,伯明翰大学的科学家团队开发了这种全新的治疗方法。该小组研发了一种细胞穿透肽(CPP),可以在数分钟内将药物带到眼睛的相关部位。 研究人员使用 CPP 方法将有效和无毒的 AMD 治疗药物滴入到小鼠、大鼠和猪的眼睛中。这种眼药水的生物活性被证明与任何其他可替代的药物相当。

参与这项研究的 Felicity de Cogan 博士表示:“CPP 药物可能通过改变给药选项对 AMD 治疗产生重大影响。与目前的治疗相比,通过眼药水可以有效地自行管理药物,并能避免不利结果和使医疗成本显着降低。”(生物谷 Bioon.com)

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    2017-05-19 lqvr
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    2017-05-19 huangdf
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    2017-05-19 muzishouyi

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