Hypertension:胰高血糖素样肽-1与动态血压呈线性相关

2014-12-10 高晓方 译 医学论坛网

瑞士一项研究表明,血浆胰高血糖素样肽-1水平与收缩压和舒张压水平均具有显著相关性。论文12月1日在线发表于《高血压》(Hypertension)。 此项研究共纳入1479例年龄为25~41岁的健康成人受试者,并利用高敏方法测定了空腹血浆胰高血糖素样肽-1水平和动态血压。评估血浆胰高血糖素样肽-1与血压指标的相关性。受试者中位年龄为38岁。 结果显示,胰高血糖素样肽-1由低到高各四分

瑞士一项研究表明,血浆胰高血糖素样肽-1水平与收缩压和舒张压水平均具有显著相关性。论文12月1日在线发表于《高血压》(Hypertension)。

此项研究共纳入1479例年龄为25~41岁的健康成人受试者,并利用高敏方法测定了空腹血浆胰高血糖素样肽-1水平和动态血压。评估血浆胰高血糖素样肽-1与血压指标的相关性。受试者中位年龄为38岁。

结果显示,胰高血糖素样肽-1由低到高各四分位组受试者平均血压分别为120.6/77.1、122.8/78.7、123.2/78.9和124.9/79.9 mmHg。多变量校正之后,胰高血糖素样肽-1与24小时动态血压呈线性相关。在单独分析中,胰高血糖素样肽-1与清醒和睡眠时血压均具有显著相关性。

原始出处:

Krisai P1, Aeschbacher S1, Schoen T1, Bossard M1, van der Stouwe JG1, Dörig L1, Todd J1, Estis J1, Risch M1, Risch L1, Conen D2.Glucagon-Like Peptide-1 and Blood Pressure in Young and Healthy Adults from the General Population.Hypertension. 2014 Dec 1. pii: HYPERTENSIONAHA.114.04718. [Epub ahead of print]


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    2015-07-02 feather89
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    2014-12-12 hbwxf
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