Brain Behav:缺血性脑卒中后晚期肌肉张力和挛缩增加

2020-04-20 MedSci原创 MedSci原创

在没有选择的情况下,关于缺血性脑卒中晚期肌张力增高和痉挛的系统性研究有限。因此,我们旨在确定脑卒中7年后肌张力增高、经典性痉挛和挛性挛缩的发生率以及脑卒中7年后肌张力增高的预测因素。

在没有选择的情况下,关于缺血性脑卒中晚期肌张力增高和痉挛的系统性研究有限。因此,我们旨在确定脑卒中7年后肌张力增高、经典性痉挛和挛性挛缩的发生率以及脑卒中7年后肌张力增高的预测因素。

 

在Sahlgrenska学院缺血性脑卒中研究中招募了年龄<70岁的急性缺血性脑卒中患者(n = 411)。使用斯堪的纳维亚脑卒中量表评估指数卒中时的症状。卒中7年后,幸存者(n = 358)被邀请进行随访评估,其中292人同意参与,288人提供了数据。根据改良的Ashworth量表的肌张力、经典性痉挛和收缩由神经科医生评估。采用logistic回归分析研究了肌张力增高与指数性卒中和复发性卒中的特征之间的关联。

 

结果显示,99名参与者(34%)的肌张力增加:上肢94人(33%),下肢72人(25%)。51名参与者(18%)出现经典性痉挛,26名参与者(9%)出现挛缩。年龄(几率比[OR]1.03[95%置信区间[CI]1.00-1.06])、臂麻痹(OR 1.76[95%CI 1.40-2.2])、失语症(OR 1.68[95%CI 1.12-2.51])和面瘫(OR 2.12[95%CI 1.10-4.07])是肌张力增加的独立预测因素。

 

综上所述,该研究结果表明,70岁以前的缺血性卒中患者中,有三分之一的患者在7年随访时显示出肌张力增加。其中一半的患者还存在经典性痉挛。年龄、臂麻痹、失语症和中风时的面瘫是中风后肌张力增加的预测因素。

 

原始出处:

 

Carina U. PerssonLukas Holmegaard, et al., Increased muscle tone and contracture late after ischemic stroke. Brain Behav. 2020 Feb; 10(2): e01509.  doi: 10.1002/brb3.1509

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    2020-07-12 zhmscau
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    2020-04-22 qjddjq
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    2020-04-21 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

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