JAHA:女性急性心梗患者的超额死亡率更高!

2017-12-15 MedSci MedSci原创

本研究的目的旨在评估急性心肌梗死治疗、全因死亡率、相对存活率和超额死亡率的性别差异。本研究纳入分析了瑞典2003年至2013年接受住院治疗的急性心肌梗死病人,在经年龄和住院时间等因素调整分析后,在全因死亡率方面无明显性别差异,在ST段抬高型心梗(STEMI)和非ST段抬高型心梗的并发症中也无明显的性别差异,但是在STEMI和非STEMI的1年和5年超额死亡率方面,女性要更高(1年:1.89 [95

本研究的目的旨在评估急性心肌梗死治疗、全因死亡率、相对存活率和超额死亡率的性别差异。本研究纳入分析了瑞典2003年至2013年接受住院治疗的急性心肌梗死病人,在经年龄和住院时间等因素调整分析后,在全因死亡率方面无明显性别差异,在ST段抬高型心梗(STEMI)和非ST段抬高型心梗的并发症中也无明显的性别差异,但是在STEMI和非STEMI的1年和5年超额死亡率方面,女性要更高(1年:1.89 [95% CI, 1.66-2.16] ; 1.20 [95% CI, 1.16-1.24], 5 年: 1.60 [95% CI, 1.48-1.72] ; 1.26 [95% CI, 1.21-1.32])。在进一步经指南推荐的治疗方法调整后,非STEMI患者的1年超额死亡率无明显性别差异,而女性在5年超额死亡率中略高一些(1.07 [95% CI, 1.02-1.12])。研究结果显示,急性心梗患者在全因死亡率中无明显性别差异,但是女性在超额死亡率方面要高于男性,这种差异在经指南推荐的治疗方法调整后会减弱。原始出处:Oras A et al.Sex Differences in Treatme

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    2018-07-01 1771ae4158m

    学习一下很不错

    0

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    2018-05-21 1771ae4158m

    学习一下很不错

    0

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    2018-04-25 1771ae4158m

    学习一下很不错

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=2049470, encodeId=465220494e0d2, content=<a href='/topic/show?id=5c2e5106290' target=_blank style='color:#2F92EE;'>#心梗患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51062, encryptionId=5c2e5106290, topicName=心梗患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e6a1280, createdName=zhanglin3079, createdTime=Fri Mar 30 02:12:00 CST 2018, time=2018-03-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=328380, encodeId=38a63283803a, content=学习一下很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/23/ac01daf0962458a9eb8c0b1e2f6ce5bc.jpg, createdBy=04b81710322, createdName=1771ae4158m, createdTime=Sun Jul 01 07:57:43 CST 2018, time=2018-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=317144, encodeId=b1f931e14493, content=学习一下很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/23/ac01daf0962458a9eb8c0b1e2f6ce5bc.jpg, createdBy=04b81710322, createdName=1771ae4158m, createdTime=Mon May 21 07:04:46 CST 2018, time=2018-05-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=309093, encodeId=bd25309093f5, content=学习一下很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/23/ac01daf0962458a9eb8c0b1e2f6ce5bc.jpg, createdBy=04b81710322, createdName=1771ae4158m, createdTime=Wed Apr 25 08:31:10 CST 2018, time=2018-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=301619, encodeId=7397301619cd, content=学习一下很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/23/ac01daf0962458a9eb8c0b1e2f6ce5bc.jpg, createdBy=04b81710322, createdName=1771ae4158m, createdTime=Sun Apr 01 06:28:31 CST 2018, time=2018-04-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=271978, encodeId=ac262e197810, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Sun Dec 24 01:09:17 CST 2017, time=2017-12-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1267650, encodeId=774a126e650d3, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Sun Dec 17 04:12:00 CST 2017, time=2017-12-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1308361, encodeId=7f1b130836104, content=<a href='/topic/show?id=8323522e503' target=_blank style='color:#2F92EE;'>#急性心梗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52275, encryptionId=8323522e503, topicName=急性心梗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fa4f352, createdName=chenlianhui, createdTime=Sun Dec 17 04:12:00 CST 2017, time=2017-12-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=269727, encodeId=b3c2269e27e1, content=学习了.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Sat Dec 16 01:03:11 CST 2017, time=2017-12-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=269615, encodeId=f2a826961555, content=大样本研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=17, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c4a5105539, createdName=lovetcm, createdTime=Fri Dec 15 14:58:35 CST 2017, time=2017-12-15, status=1, ipAttribution=)]
    2018-04-01 1771ae4158m

    学习一下很不错

    0

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    2017-12-24 1209e435m98(暂无昵称)

    学习了.谢谢分享

    0

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    2017-12-17 柳叶一刀
  8. [GetPortalCommentsPageByObjectIdResponse(id=2049470, encodeId=465220494e0d2, content=<a href='/topic/show?id=5c2e5106290' target=_blank style='color:#2F92EE;'>#心梗患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51062, encryptionId=5c2e5106290, topicName=心梗患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e6a1280, createdName=zhanglin3079, createdTime=Fri Mar 30 02:12:00 CST 2018, time=2018-03-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=328380, encodeId=38a63283803a, content=学习一下很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/23/ac01daf0962458a9eb8c0b1e2f6ce5bc.jpg, createdBy=04b81710322, createdName=1771ae4158m, createdTime=Sun Jul 01 07:57:43 CST 2018, time=2018-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=317144, encodeId=b1f931e14493, content=学习一下很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/23/ac01daf0962458a9eb8c0b1e2f6ce5bc.jpg, createdBy=04b81710322, createdName=1771ae4158m, createdTime=Mon May 21 07:04:46 CST 2018, time=2018-05-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=309093, encodeId=bd25309093f5, content=学习一下很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/23/ac01daf0962458a9eb8c0b1e2f6ce5bc.jpg, createdBy=04b81710322, createdName=1771ae4158m, createdTime=Wed Apr 25 08:31:10 CST 2018, time=2018-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=301619, encodeId=7397301619cd, content=学习一下很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/23/ac01daf0962458a9eb8c0b1e2f6ce5bc.jpg, createdBy=04b81710322, createdName=1771ae4158m, createdTime=Sun Apr 01 06:28:31 CST 2018, time=2018-04-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=271978, encodeId=ac262e197810, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Sun Dec 24 01:09:17 CST 2017, time=2017-12-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1267650, encodeId=774a126e650d3, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Sun Dec 17 04:12:00 CST 2017, time=2017-12-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1308361, encodeId=7f1b130836104, content=<a href='/topic/show?id=8323522e503' target=_blank style='color:#2F92EE;'>#急性心梗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52275, encryptionId=8323522e503, topicName=急性心梗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fa4f352, createdName=chenlianhui, createdTime=Sun Dec 17 04:12:00 CST 2017, time=2017-12-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=269727, encodeId=b3c2269e27e1, content=学习了.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Sat Dec 16 01:03:11 CST 2017, time=2017-12-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=269615, encodeId=f2a826961555, content=大样本研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=17, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c4a5105539, createdName=lovetcm, createdTime=Fri Dec 15 14:58:35 CST 2017, time=2017-12-15, status=1, ipAttribution=)]
  9. [GetPortalCommentsPageByObjectIdResponse(id=2049470, encodeId=465220494e0d2, content=<a href='/topic/show?id=5c2e5106290' target=_blank style='color:#2F92EE;'>#心梗患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51062, encryptionId=5c2e5106290, topicName=心梗患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e6a1280, createdName=zhanglin3079, createdTime=Fri Mar 30 02:12:00 CST 2018, time=2018-03-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=328380, encodeId=38a63283803a, content=学习一下很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/23/ac01daf0962458a9eb8c0b1e2f6ce5bc.jpg, createdBy=04b81710322, createdName=1771ae4158m, createdTime=Sun Jul 01 07:57:43 CST 2018, time=2018-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=317144, encodeId=b1f931e14493, content=学习一下很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/23/ac01daf0962458a9eb8c0b1e2f6ce5bc.jpg, createdBy=04b81710322, createdName=1771ae4158m, createdTime=Mon May 21 07:04:46 CST 2018, time=2018-05-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=309093, encodeId=bd25309093f5, content=学习一下很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/23/ac01daf0962458a9eb8c0b1e2f6ce5bc.jpg, createdBy=04b81710322, createdName=1771ae4158m, createdTime=Wed Apr 25 08:31:10 CST 2018, time=2018-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=301619, encodeId=7397301619cd, content=学习一下很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/23/ac01daf0962458a9eb8c0b1e2f6ce5bc.jpg, createdBy=04b81710322, createdName=1771ae4158m, createdTime=Sun Apr 01 06:28:31 CST 2018, time=2018-04-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=271978, encodeId=ac262e197810, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Sun Dec 24 01:09:17 CST 2017, time=2017-12-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1267650, encodeId=774a126e650d3, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Sun Dec 17 04:12:00 CST 2017, time=2017-12-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1308361, encodeId=7f1b130836104, content=<a href='/topic/show?id=8323522e503' target=_blank style='color:#2F92EE;'>#急性心梗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52275, encryptionId=8323522e503, topicName=急性心梗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fa4f352, createdName=chenlianhui, createdTime=Sun Dec 17 04:12:00 CST 2017, time=2017-12-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=269727, encodeId=b3c2269e27e1, content=学习了.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Sat Dec 16 01:03:11 CST 2017, time=2017-12-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=269615, encodeId=f2a826961555, content=大样本研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=17, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c4a5105539, createdName=lovetcm, createdTime=Fri Dec 15 14:58:35 CST 2017, time=2017-12-15, status=1, ipAttribution=)]
    2017-12-16 1209e435m98(暂无昵称)

    学习了.谢谢分享!

    0

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    2017-12-15 lovetcm

    大样本研究

    0

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目前,对心梗后的左房重塑的认识尚浅。本研究的目的旨在利用心肌梗塞的猪模型来评估左房结构重塑的能力,并阐明左房重塑是如何影响二尖瓣返流的进展。本研究共建立了3个动物模型:1) 近端左回旋支(LCX)包括左房分支冠状动脉闭塞(左房梗塞组);2)近端左回旋支(LCX)不包括左房分支冠状动脉闭塞(LCx组);3)左前降支(LAD)闭塞(LAD组)。通过心脏磁共振扫描对左房、左室重塑和缺血性二尖瓣返流进行评

JACC:依普利酮可减少房颤负担,但不影响心房电重构

醛固酮抑制剂依普利酮(EPL)可以减少收缩型心衰患者房颤的发病风险,然而,其具体机制尚未阐明。本研究将34只房性心动过速的山羊(13 ± 1周)随机分成每日口服EPL组(n=19)和糖片对照组(n=14),主要终点事件是连续七天的房颤(n=29)或持续23周的心动过速(n=5)。结果显示,EPL可以明显减少房颤发展过程中左房的扩张率。与对照组相比,口服EPL的山羊的心房平滑肌肌动蛋白、Ⅲ型胶原表达

JACC:低密度脂蛋白胆固醇处于正常水平就安全了?

传统上认为,缺乏心血管危险因素(CVRFs)患动脉粥样硬化的风险低,然而,没有CVRFs的个体仍报道有不良心血管事件的发生。本研究的目的旨在评估分析没有CVRF的个体患亚临床动脉粥样硬化的危险预测因素。本研究纳入了PESA临床试验中无传统心血管危险因素的个体(n = 1,779; 平均年龄为45.0 ± 4.1 岁,女性占 50.3%)。无传统心血管危险因素包括一下几点:不吸烟,血压<140/90

JACC:冠心病伴糖尿病的冠脉搭桥远期疗效优于介入治疗

既往随机临床试验数据表明对于多血管冠心病(MV-CAD)伴糖尿病患者,冠脉搭桥手术的疗效要优于经皮介入治疗(PCI)。然而,这种优越性对现实临床中稳定型缺血性心脏病(SIHD)和急性冠脉综合征(ACS)患者是否存在尚属未知。在来自不列颠哥伦比亚的一个大型人群样本研究中,评估比较了2007年至2014年接受冠脉血流重建的所以糖尿病患者的心血管结局预后(n = 4661, 2947名为ACS),主要终