Thorax:运动训练可以改善间质性肺疾病患者病情

2017-02-18 xing.T MedSci原创

由此可见,运动训练对于各种间质性肺病患者都是有效的,对石棉肺和IPF患者具有临床意义上的益处。成功的运动训练可以对轻度ILD患者产生最大程度地改善和持续的治疗效应。

关于运动训练与所有间质性肺疾病(ILDs)之间的临床相关性仍然存在不确定性。近日,胸部疾病领域权威杂志Thorax上发表了一篇研究文章,研究人员明确运动训练对不同病因和严重程度的间质性肺病患者的影响。

研究人员将142例ILD患者(61例特发性肺纤维化(IPF)患者,22例石棉肺患者,23例结缔组织疾病相关的ILD(CTD-ILD)患者和36例其他病因患者)被随机分配,接受8 周的监督运动训练或常规护理。研究人员在研究之初、9周和6个月分别进行六分钟步行距离(6MWD)、慢性呼吸疾病问卷(CRDQ)、圣乔治呼吸问卷IPF专用版(SGRQ-I)和改良医学研究理事会呼吸困难评分测量。

在ILD患者中,运动训练显著增加6MWD(25m,95%可信区间为2至47m)和健康相关的生活质量(CRDQ和SGRQ-I)。相比于CTD-ILD患者,石棉肺和IPF患者6MWD、CRDQ、SGRQ-I和呼吸困难改善更加明显,但亚组间差异并不显著。除了CTD-ILD患者其益处在6个月后减弱。较低的基础6MWD和较差的基础症状患者能从运动训练中获得更大的6MWD和相关症状改善。在那些根据协议成功地完成运动处方的患者能够获得更大的收益。在6 月,持续改善的6MWD和症状与更好的基线肺功能和较低的肺动脉高压有关。

由此可见,运动训练对于各种间质性肺病患者都是有效的,对石棉肺和IPF患者具有临床意义上的益处。成功的运动训练可以对轻度ILD患者产生最大程度地改善和持续的治疗效应。

原始出处:


Leona M Dowman, et al. The evidence of benefits of exercise training in interstitial lung disease: a randomised controlled trial.Thorax. 2017. http://thorax.bmj.com/content/early/2017/02/17/thoraxjnl-2016-208638

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    2017-02-26 wmu姿

    管住嘴迈开腿,一切都很美

    0

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    2017-02-22 1e10c84am36(暂无匿称)

    文章很不错哦

    0

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  8. [GetPortalCommentsPageByObjectIdResponse(id=1764993, encodeId=f9f91e64993ab, content=<a href='/topic/show?id=df00e086653' target=_blank style='color:#2F92EE;'>#病情#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70866, encryptionId=df00e086653, topicName=病情)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d1dc37824931, createdName=ms7524819409032184, createdTime=Thu Jan 11 12:26:00 CST 2018, time=2018-01-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1954913, encodeId=464419549139d, content=<a href='/topic/show?id=d5079422460' target=_blank style='color:#2F92EE;'>#运动训练#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94224, encryptionId=d5079422460, topicName=运动训练)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Mon Sep 25 23:26:00 CST 2017, time=2017-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1815755, encodeId=d3101815e5523, content=<a href='/topic/show?id=82e99e291b0' target=_blank style='color:#2F92EE;'>#间质性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97291, encryptionId=82e99e291b0, topicName=间质性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=99cf2500102, createdName=zjshifan_98647306, createdTime=Sat Nov 11 17:26:00 CST 2017, time=2017-11-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1798971, encodeId=c08b1e9897193, content=<a href='/topic/show?id=38e0e0670ff' target=_blank style='color:#2F92EE;'>#疾病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70670, encryptionId=38e0e0670ff, topicName=疾病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c859411, createdName=hmwwww, createdTime=Sun Jul 16 19:26:00 CST 2017, time=2017-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=177948, encodeId=6e8e1e794861, content=管住嘴迈开腿,一切都很美, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=071c2012037, createdName=wmu姿, createdTime=Sun Feb 26 10:19:13 CST 2017, time=2017-02-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=177449, encodeId=112c1e744960, content=文章很不错哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Wed Feb 22 14:23:49 CST 2017, time=2017-02-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1440632, encodeId=c17414406327c, content=<a href='/topic/show?id=b5529e294d4' target=_blank style='color:#2F92EE;'>#间质性肺疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97294, encryptionId=b5529e294d4, topicName=间质性肺疾病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=09464745891, createdName=1179102698_36768927, createdTime=Mon Feb 20 03:26:00 CST 2017, time=2017-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=176849, encodeId=fa1c1e68492b, content=有用,很多肺病患者不愿意运动, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRhMvhh5icA01VlaGzCZQ0VOzgHK4JVfic4aufJ9ic3NibwHq6QCpLFptGLWLOyZms63YicPa1vgcuVlT2/0, createdBy=b3172018021, createdName=Dr.赵, createdTime=Sat Feb 18 17:35:41 CST 2017, time=2017-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=176843, encodeId=c0b01e6843a9, content=学习了,谢谢啦!, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLK1wzJZRTON4gxYUibhUyOypBwMibC4R7SsppicGhz5Ogoy0VVq4CWnqaD2Moeib8RWxI5lOiaVmnxpan/0, createdBy=c53f1730331, createdName=tanxingdoctor, createdTime=Sat Feb 18 17:09:35 CST 2017, time=2017-02-18, status=1, ipAttribution=)]
    2017-02-18 Dr.赵

    有用,很多肺病患者不愿意运动

    0

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    2017-02-18 tanxingdoctor

    学习了,谢谢啦!

    0

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