Hypertension:儿童和成人血压升高对成人动脉僵硬度的影响!

2017-07-04 xing.T MedSci原创

由此可见,这些结果强调了血压控制在心血管疾病一级预防中的重要性。

儿童期血压升高与成人动脉硬化增加有关,它是心血管和各种原因死亡率的独立预测因子。从童年到成年的有利的血压变化和成人动脉硬化高风险还没有被报道。近日,心血管权威杂志Hypertension上发表了一篇研究文章,研究人员对1540名白色人群从基线随访27年(1980、6-18岁)后旨在评估了儿童和成人血压对成年后脉搏波传导速度(PWV)的影响。

根据国家高血压教育计划表,研究人员定义了儿童血压升高。在成年后,如果收缩压升高≥120mmHg,舒张压≥80mmHg,或自称使用降压药物被列为高血压患者。通过整体阻抗心脏成像法在2007年测量了受试者的PWV,并且升高的PWV被定义为PWV值超过年龄、性别和心率特异性的第八十百分位数。

研究人员发现持续血压升高和儿童期血压正常但成人期血压升高的个体成年PWV升高的风险增加(分别有相对风险(95%可信区间)为3.18[2.22-4.55]和2.64[1.79-3.88]),与(成人和儿童)血压均正常的个体相比。相反,儿童期血压升高但成年期没有升高的个人PWV升高的风险并未显著增加(相对风险(95%可信区间)为1.26[0.80-1.99])。当儿童和成人血压升高的定义不同时,结果仍是一致的。

由此可见,这些结果强调了血压控制在心血管疾病一级预防中的重要性。

原始出处:

Heikki Aatola,,et al. Influence of Child and Adult Elevated Blood Pressure on Adult Arterial Stiffness The Cardiovascular Risk in Young Finns Study.Hypertension.2017. https://doi.org/10.1161/HYPERTENSIONAHA.117.09444

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    2017-07-10 大爰

    学习了谢谢分享!!

    0

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    2017-07-04 flysky120

    学习一下知识了

    0

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    2017-07-04 杨利洪

    学习了,分享了

    0

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