Cerebral Cortex:社会经济地位与认知能力之间的关系部分与脑结构有关

2022-03-02 影像小生 MedSci原创

更高的社会经济地位(SES)对大脑和认知具有促进和保护作用。教育、收入、一般认知能力(GCA)和脑容量之间的正相关关系在发育、成年和老龄化中已经被报道。虽然较高的社会经济地位被视为促进或保护因素,但较

更高的社会经济地位(SES)对大脑和认知具有促进和保护作用。教育、收入、一般认知能力(GCA)和脑容量之间的正相关关系在发育、成年和老龄化中已经被报道。虽然较高的社会经济地位被视为促进或保护因素,但较低的社会经济地位被表明会对大脑和认知功能造成风险,特别是在儿童时期。

Kristine B Walhovd等在Cerebral Cortex发表题为Education and Income Show Heterogeneous Relationships to Lifespan Brain and Cognitive Differences Across European and US Cohorts的研究文章,旨在研究 SES、脑容量和认知能力之间的关系是否因年龄和国籍而异。

研究了包含欧洲和美国队列(4-97 岁,N = 500 000;54 000 w/脑成像)。所有关联的队列之间存在显着的异质性。

研究结果发现教育与颅内体积(ICV) 和总灰质 (GM) 体积呈正相关。收入与 ICV 相关,但与 GM 无关。没有观察到作为年龄函数的关联的可靠差异。

GCA对皮质体积、面积和厚度的影响。

GMICV与年龄相关的差异。

认知(GCA)与教育、收入、GMICV的关系。

GM和ICV与教育和收入的关系。

与欧洲队列相比,美国的 SES 与大脑和认知的相关性更强。样本代表性各不相同,本研究无法确定跨队列关联差异的潜在机制。神经解剖体积的差异部分解释了 SES-认知关系。SES 与 ICV 的相关性比与 GM 的关系更密切,这意味着成年期的 SES-认知关系不太可能基于对衰老过程中 GM 体积的神经保护作用。相对较强的 SES-ICV 关联与在生命早期建立的 SES-脑容量关系兼容,因为 ICV 在儿童期稳定。研究结果强调,SES 与大脑和认知没有统一的关联或影响。相对较强的 SES-ICV 关联与在生命早期建立的 SES-脑容量关系兼容,因为 ICV 在儿童期稳定。研究结果强调,SES 与大脑和认知没有统一的关联或影响。相对较强的 SES-ICV 关联与在生命早期建立的 SES-脑容量关系兼容,因为 ICV 在儿童期稳定。研究结果强调,SES 与大脑和认知没有统一的关联或影响。

总之,通过这种多队列研究方法,在美国和欧洲的人群中,包括人类寿命的所有年龄段,SES的大脑认知关系存在显著的异质性。这表明SES不会以任何一致的方式影响大脑或认知,反之亦然。与欧洲人相比,美国人的社会地位和大脑结构之间存在更强的正相关关系。ICV与SES的相关性比ICV对照GM的相关性更强。这表明在衰老过程中主要是发育作用而不是神经保护作用ICV和GM体积可以部分解释教育- GCA关系和收入-GCA关系的差异。

在欧洲和美国的主要人群中,SES与大脑和认知的关系存在显著的异质性。基于这些结果,SES对认知的影响不太可能是基于衰老过程中对GM体积的神经保护作用。相反,在大脑发育过程中建立的社会经济地位关系可能贯穿整个生命周期。在这方面,美国人的收入和教育与神经解剖学体积的关系比欧洲人的更强,这表明在工业化国家的不同人群中,社会经济地位并不相同。结果还表明,社会经济地位与认知能力之间的部分关系可能与大脑结构的差异有关。这并不意味着SES通过其对大脑的影响来因果影响认知,只是说SES是一个标志,它以部分相似的方式与大脑和认知相关。这些发现,包括在不同人群中显著的影响异质性,对我们理解社会经济地位是否、何时以及如何影响大脑和认知有意义。

原文出处

Kristine B Walhovd, Anders M Fjell, Yunpeng Wang, Inge K Amlien, Athanasia M Mowinckel, Ulman Lindenberger, Sandra Düzel, David Bartrés-Faz, Klaus P Ebmeier, Christian A Drevon, William F C Baaré, Paolo Ghisletta, Louise Baruël Johansen, Rogier A Kievit, Richard N Henson, Kathrine Skak Madsen, Lars Nyberg, Jennifer R Harris, Cristina Solé-Padullés, Sara Pudas, Øystein Sørensen, René Westerhausen, Enikő Zsoldos, Laura Nawijn, Torkild Hovde Lyngstad, Sana Suri, Brenda Penninx, Ole J Rogeberg, Andreas M Brandmaier, Education and Income Show Heterogeneous Relationships to Lifespan Brain and Cognitive Differences Across European and US Cohorts, Cerebral Cortex, Volume 32, Issue 4, 15 February 2022, Pages 839–854, https://doi.org/10.1093/cercor/bhab248

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  4. [GetPortalCommentsPageByObjectIdResponse(id=1805528, encodeId=56d318055286d, content=<a href='/topic/show?id=cc8ae8341fc' target=_blank style='color:#2F92EE;'>#经济地位#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78341, encryptionId=cc8ae8341fc, topicName=经济地位)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=71f1477, createdName=s_pl2008, createdTime=Fri Jun 17 00:25:27 CST 2022, time=2022-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1707367, encodeId=a1b71e0736711, content=<a href='/topic/show?id=63764499be' target=_blank style='color:#2F92EE;'>#cerebral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4499, encryptionId=63764499be, topicName=cerebral)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a56f31414366, createdName=ms55066533437992, createdTime=Sun Jan 01 04:25:27 CST 2023, time=2023-01-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1924513, encodeId=ff971924513e4, content=<a href='/topic/show?id=a7f2e3997c4' target=_blank style='color:#2F92EE;'>#社会经济#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73997, encryptionId=a7f2e3997c4, topicName=社会经济)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=医者仁心, createdTime=Sun Aug 21 07:25:27 CST 2022, time=2022-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1199140, encodeId=8d8a1199140e5, content=社会地位与认知关系, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b2b82397018, createdName=12346c4dm64暂无昵称, createdTime=Thu Mar 03 18:33:59 CST 2022, time=2022-03-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1199057, encodeId=d72c119905eb4, content=长期选择的结果吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=62af5100837, createdName=145f35c5m30(暂无昵称), createdTime=Thu Mar 03 14:55:26 CST 2022, time=2022-03-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1198757, encodeId=45481198e573c, content=霍……努力新方向新动力啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210127/50a003c4097845e182c08afd64d8a509/bd766dfebe9c40e0bca2dae964601bdc.jpg, createdBy=22de5454917, createdName=carrotlyl, createdTime=Wed Mar 02 16:07:35 CST 2022, time=2022-03-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1198693, encodeId=4009119869383, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e9be6495931, createdName=ms8000000018254969, createdTime=Wed Mar 02 13:06:32 CST 2022, time=2022-03-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1457174, encodeId=3fb5145e1740d, content=<a href='/topic/show?id=94f5e400123' target=_blank style='color:#2F92EE;'>#社会经济地位#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74001, encryptionId=94f5e400123, topicName=社会经济地位)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c6025850709, createdName=chenwq10, createdTime=Fri Feb 25 08:25:27 CST 2022, time=2022-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1556537, encodeId=adc2155653eb8, content=<a href='/topic/show?id=ab7e85001cf' target=_blank style='color:#2F92EE;'>#脑结构#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85001, encryptionId=ab7e85001cf, topicName=脑结构)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4f3114785325, createdName=wmr116, createdTime=Fri Feb 25 08:25:27 CST 2022, time=2022-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1617078, encodeId=bb10161e0781d, content=<a href='/topic/show?id=e660e3936c0' target=_blank style='color:#2F92EE;'>#社会#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73936, encryptionId=e660e3936c0, topicName=社会)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e6de19781024, createdName=ms705947299214030, createdTime=Fri Feb 25 08:25:27 CST 2022, time=2022-02-25, status=1, ipAttribution=)]
    2022-03-03 12346c4dm64暂无昵称

    社会地位与认知关系

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1805528, encodeId=56d318055286d, content=<a href='/topic/show?id=cc8ae8341fc' target=_blank style='color:#2F92EE;'>#经济地位#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78341, encryptionId=cc8ae8341fc, topicName=经济地位)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=71f1477, createdName=s_pl2008, createdTime=Fri Jun 17 00:25:27 CST 2022, time=2022-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1707367, encodeId=a1b71e0736711, content=<a href='/topic/show?id=63764499be' target=_blank style='color:#2F92EE;'>#cerebral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4499, encryptionId=63764499be, topicName=cerebral)], attachment=null, authenticateStatus=null, createdAvatar=null, 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02 16:07:35 CST 2022, time=2022-03-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1198693, encodeId=4009119869383, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e9be6495931, createdName=ms8000000018254969, createdTime=Wed Mar 02 13:06:32 CST 2022, time=2022-03-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1457174, encodeId=3fb5145e1740d, content=<a href='/topic/show?id=94f5e400123' target=_blank style='color:#2F92EE;'>#社会经济地位#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74001, encryptionId=94f5e400123, topicName=社会经济地位)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c6025850709, createdName=chenwq10, createdTime=Fri Feb 25 08:25:27 CST 2022, time=2022-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1556537, encodeId=adc2155653eb8, content=<a href='/topic/show?id=ab7e85001cf' target=_blank style='color:#2F92EE;'>#脑结构#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85001, encryptionId=ab7e85001cf, topicName=脑结构)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4f3114785325, createdName=wmr116, createdTime=Fri Feb 25 08:25:27 CST 2022, time=2022-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1617078, encodeId=bb10161e0781d, content=<a href='/topic/show?id=e660e3936c0' target=_blank style='color:#2F92EE;'>#社会#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73936, encryptionId=e660e3936c0, topicName=社会)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e6de19781024, createdName=ms705947299214030, createdTime=Fri Feb 25 08:25:27 CST 2022, time=2022-02-25, status=1, ipAttribution=)]
    2022-03-03 145f35c5m30(暂无昵称)

    长期选择的结果吗

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1805528, encodeId=56d318055286d, content=<a href='/topic/show?id=cc8ae8341fc' target=_blank style='color:#2F92EE;'>#经济地位#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78341, encryptionId=cc8ae8341fc, topicName=经济地位)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=71f1477, createdName=s_pl2008, createdTime=Fri Jun 17 00:25:27 CST 2022, time=2022-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1707367, encodeId=a1b71e0736711, content=<a href='/topic/show?id=63764499be' target=_blank style='color:#2F92EE;'>#cerebral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4499, encryptionId=63764499be, topicName=cerebral)], attachment=null, authenticateStatus=null, createdAvatar=null, 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createdName=12346c4dm64暂无昵称, createdTime=Thu Mar 03 18:33:59 CST 2022, time=2022-03-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1199057, encodeId=d72c119905eb4, content=长期选择的结果吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=62af5100837, createdName=145f35c5m30(暂无昵称), createdTime=Thu Mar 03 14:55:26 CST 2022, time=2022-03-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1198757, encodeId=45481198e573c, content=霍……努力新方向新动力啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210127/50a003c4097845e182c08afd64d8a509/bd766dfebe9c40e0bca2dae964601bdc.jpg, createdBy=22de5454917, createdName=carrotlyl, createdTime=Wed Mar 02 16:07:35 CST 2022, time=2022-03-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1198693, encodeId=4009119869383, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e9be6495931, createdName=ms8000000018254969, createdTime=Wed Mar 02 13:06:32 CST 2022, time=2022-03-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1457174, encodeId=3fb5145e1740d, content=<a href='/topic/show?id=94f5e400123' target=_blank style='color:#2F92EE;'>#社会经济地位#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74001, encryptionId=94f5e400123, topicName=社会经济地位)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c6025850709, createdName=chenwq10, createdTime=Fri Feb 25 08:25:27 CST 2022, time=2022-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1556537, encodeId=adc2155653eb8, content=<a href='/topic/show?id=ab7e85001cf' target=_blank style='color:#2F92EE;'>#脑结构#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85001, encryptionId=ab7e85001cf, topicName=脑结构)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4f3114785325, createdName=wmr116, createdTime=Fri Feb 25 08:25:27 CST 2022, time=2022-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1617078, encodeId=bb10161e0781d, content=<a href='/topic/show?id=e660e3936c0' target=_blank style='color:#2F92EE;'>#社会#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73936, encryptionId=e660e3936c0, topicName=社会)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e6de19781024, createdName=ms705947299214030, createdTime=Fri Feb 25 08:25:27 CST 2022, time=2022-02-25, status=1, ipAttribution=)]
    2022-03-02 carrotlyl

    霍……努力新方向新动力啊

    0

  7. 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createdName=12346c4dm64暂无昵称, createdTime=Thu Mar 03 18:33:59 CST 2022, time=2022-03-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1199057, encodeId=d72c119905eb4, content=长期选择的结果吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=62af5100837, createdName=145f35c5m30(暂无昵称), createdTime=Thu Mar 03 14:55:26 CST 2022, time=2022-03-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1198757, encodeId=45481198e573c, content=霍……努力新方向新动力啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210127/50a003c4097845e182c08afd64d8a509/bd766dfebe9c40e0bca2dae964601bdc.jpg, createdBy=22de5454917, createdName=carrotlyl, createdTime=Wed Mar 02 16:07:35 CST 2022, time=2022-03-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1198693, encodeId=4009119869383, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e9be6495931, createdName=ms8000000018254969, createdTime=Wed Mar 02 13:06:32 CST 2022, time=2022-03-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1457174, encodeId=3fb5145e1740d, content=<a href='/topic/show?id=94f5e400123' target=_blank style='color:#2F92EE;'>#社会经济地位#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74001, encryptionId=94f5e400123, topicName=社会经济地位)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c6025850709, createdName=chenwq10, createdTime=Fri Feb 25 08:25:27 CST 2022, time=2022-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1556537, encodeId=adc2155653eb8, content=<a href='/topic/show?id=ab7e85001cf' target=_blank style='color:#2F92EE;'>#脑结构#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85001, encryptionId=ab7e85001cf, topicName=脑结构)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4f3114785325, createdName=wmr116, createdTime=Fri Feb 25 08:25:27 CST 2022, time=2022-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1617078, encodeId=bb10161e0781d, content=<a href='/topic/show?id=e660e3936c0' target=_blank style='color:#2F92EE;'>#社会#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73936, encryptionId=e660e3936c0, topicName=社会)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e6de19781024, createdName=ms705947299214030, createdTime=Fri Feb 25 08:25:27 CST 2022, time=2022-02-25, status=1, ipAttribution=)]
    2022-03-02 ms8000000018254969

    学习

    0

  8. 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createdName=12346c4dm64暂无昵称, createdTime=Thu Mar 03 18:33:59 CST 2022, time=2022-03-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1199057, encodeId=d72c119905eb4, content=长期选择的结果吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=62af5100837, createdName=145f35c5m30(暂无昵称), createdTime=Thu Mar 03 14:55:26 CST 2022, time=2022-03-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1198757, encodeId=45481198e573c, content=霍……努力新方向新动力啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210127/50a003c4097845e182c08afd64d8a509/bd766dfebe9c40e0bca2dae964601bdc.jpg, createdBy=22de5454917, createdName=carrotlyl, createdTime=Wed Mar 02 16:07:35 CST 2022, time=2022-03-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1198693, encodeId=4009119869383, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e9be6495931, createdName=ms8000000018254969, createdTime=Wed Mar 02 13:06:32 CST 2022, time=2022-03-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1457174, encodeId=3fb5145e1740d, content=<a href='/topic/show?id=94f5e400123' target=_blank style='color:#2F92EE;'>#社会经济地位#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74001, encryptionId=94f5e400123, topicName=社会经济地位)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c6025850709, createdName=chenwq10, createdTime=Fri Feb 25 08:25:27 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  9. 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02 16:07:35 CST 2022, time=2022-03-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1198693, encodeId=4009119869383, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e9be6495931, createdName=ms8000000018254969, createdTime=Wed Mar 02 13:06:32 CST 2022, time=2022-03-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1457174, encodeId=3fb5145e1740d, content=<a href='/topic/show?id=94f5e400123' target=_blank style='color:#2F92EE;'>#社会经济地位#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74001, encryptionId=94f5e400123, topicName=社会经济地位)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c6025850709, createdName=chenwq10, createdTime=Fri Feb 25 08:25:27 CST 2022, time=2022-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1556537, encodeId=adc2155653eb8, content=<a href='/topic/show?id=ab7e85001cf' target=_blank style='color:#2F92EE;'>#脑结构#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85001, encryptionId=ab7e85001cf, topicName=脑结构)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4f3114785325, createdName=wmr116, createdTime=Fri Feb 25 08:25:27 CST 2022, time=2022-02-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1617078, encodeId=bb10161e0781d, content=<a href='/topic/show?id=e660e3936c0' target=_blank style='color:#2F92EE;'>#社会#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73936, encryptionId=e660e3936c0, topicName=社会)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e6de19781024, createdName=ms705947299214030, createdTime=Fri Feb 25 08:25:27 CST 2022, time=2022-02-25, status=1, ipAttribution=)]
    2022-02-25 wmr116
  10. 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