J Diet Suppl:布朗蒂果实提取物具有优异的抗菌作用

2018-06-30 MedSci MedSci原创

https://www.ncbi.nlm.nih.gov/pubmed/29958029

作为化合物替代品的植物提取物通常用于制药和食品工业。提取物的抗菌性质主要作为药物成分使用。由于传染病的高发病率,有必要确定更多能够治疗疾病的药物。既往研究报道了不同植物提取物的抗氧化作用。本研究旨在探究布氏锥栗果实提取物的抗氧化活性、总酚和类黄酮的含量,以及抗菌效果。

在该研究中,使用70%的乙醇通过浸渍提取布氏锥栗果实提取物。使用Folin-Ciocalceu试剂和没食子酸等价物测定总酚含量,并与丁基化羟基甲苯(BHT)相比,使用2,2-二苯基-1-苦基偕腙(DPPH)测量抗氧化活性。通过肉汤微量稀释法、最小抑制浓度(MIC)和最小杀菌浓度(MBC)的测量来探究其抗菌效果。然后研究不同浓度提取物对金黄色葡萄球菌和粪肠球菌生长的作用,并与万古霉素和呋喃妥因比较。

结果表明,奎宁果水果醇提取物的抗氧化活性高于BHT。总酚含量为3.010mg GAE/g DW。黄酮醇和类黄酮含量分别为1.813和0.654mg/g。提取物对两种细菌都具有明显的抑制作用,且金黄色葡萄球菌较粪肠球菌对提取物的抗菌作用更敏感。

综上所述,该研究结果表明,布朗蒂果实提取物具有较强的抗氧化作用,含有大量的酚类,黄酮醇和类黄酮化合物,并可抑制细菌生长。

原始出处:

Aleebrahim-Dehkordy E, Rafieian-Kopaei M, et al.,  In Vitro Evaluation of Antioxidant Activity and Antibacterial Effects and Measurement of Total Phenolic and Flavonoid Contents of Quercus brantii L. Fruit Extract. J Diet Suppl. 2018 Jun 29:1-9. doi: 10.1080/19390211.2018.1470126.

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    2018-07-02 zhouqu_8
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    2018-07-02 lg.zhao