筛选条件 共查询到44条结果
排序方式
Anlotinib combined with TQB2450 in patients with platinum-resistant or -refractory ovarian cancer: A multi-center, single-arm, phase 1b trial

期刊: CELL REPORTS MEDICINE, 2022; 3 (7)

This is a phase Ib study of anlotinib plus a programmed death-ligand 1 (PD-L1) inhibitor TQB2450 for plat-inum-resistant or-refractory ovarian cancer.......

Human early syncytiotrophoblasts are highly susceptible to SARS-CoV-2 infection

期刊: CELL REPORTS MEDICINE, 2022; 3 (12)

Direct in vivo investigation of human placenta trophoblast's susceptibility to SARS-CoV-2 is challenging. Here we report that human trophoblast stem c......

Reward learning in the development and maintenance of chronic back pain

期刊: CELL REPORTS MEDICINE, 2022; 3 (7)

Treating and preventing chronic pain require our understanding of how it develops and maintains. Loffler et al. (2022)(1) demonstrate that distinct op......

Correlation of gut microbiota and metabolic functions with the antibody response to the BBIBP-CorV vaccine

期刊: CELL REPORTS MEDICINE, 2022; 3 (10)

Increasing evidence indicates that gut microbiota may play a key role in vaccination immunity. Here, we investigate whether the human gut microbiota a......

Inhibiting 31 beta HSD1 to eliminate the oncogenic effects of progesterone in prostate cancer

期刊: CELL REPORTS MEDICINE, 2022; 3 (3)

Prostate cancer continuously progresses following deprivation of circulating androgens originating from the testis and adrenal glands, indicating the ......

Radiogenomic analysis reveals tumor heterogeneity of triple-negative breast cancer

期刊: CELL REPORTS MEDICINE, 2022; 3 (7)

Triple-negative breast cancer (TNBC) is a subset of breast cancer with an adverse prognosis and significant tumor heterogeneity. Here, we extract quan......

PSMG2-controlled proteasome-autophagy balance mediates the tolerance for MEK-targeted therapy in triple-negative breast cancer

期刊: CELL REPORTS MEDICINE, 2022; 3 (9)

Although the MAPK pathway is aberrantly activated in triple-negative breast cancers (TNBCs), the clinical outcome of MEK-targeted therapy is still poo......

Time-restricted eating with or without low-carbohydrate diet reduces visceral fat and improves metabolic syndrome: A randomized trial

期刊: CELL REPORTS MEDICINE, 2022; 3 (10)

Overconsumption of carbohydrate-rich food combined with adverse eating patterns contributes to the increasing incidence of metabolic syndrome (MetS) i......

More efforts are needed for background surveys of zoonotic coronaviruses in animals

期刊: CELL REPORTS MEDICINE, 2022; 3 (3)

Recently, a novel dog-origin coronavirus has been found in humans. The low similarity between the receptor-binding domain from this novel virus and ot......

Optimal target saturation of ligand-blocking anti-GITR antibody IBI37G5 dictates Fc gamma R-independent GITR agonism and antitumor activity

期刊: CELL REPORTS MEDICINE, 2022; 3 (6)

Glucocorticoid-induced tumor necrosis factor receptor (GITR) is a co-stimulatory receptor and an important target for cancer immunotherapy. We herein ......

Rui-Hua Xu

期刊: CELL REPORTS MEDICINE, 2022; 3 (4)

Rui-Hua Xu completed the REGOTORI trial that showed a novel combination regimen, regorafenib plus toripalimab, improved the efficacy and survival of r......

A molecularly engineered, broad-spectrum anti-coronavirus lectin inhibits SARS-CoV-2 and MERS-CoV infection in vivo

期刊: CELL REPORTS MEDICINE, 2022; 3 (10)

Pan-coronavirus'' antivirals targeting conserved viral components can be designed. Here, we show that the rationally engineered H84T-banana lectin (H8......

Spatial heterogeneity of infiltrating T cells in high- grade serous ovarian cancer revealed by multi-omics analysis

期刊: CELL REPORTS MEDICINE, 2022; 3 (12)

Tumor-infiltrating lymphocytes (TILs), especially CD8+ TILs, represent a favorable prognostic factor in high-grade serous ovarian cancer (HGSOC) and o......

共44条页码: 1/3页15条/页