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Non-Vitamin K Antagonist Oral Anticoagulants (NOACs) Versus Warfarin in Patients with Atrial Fibrillation and (Morbid) Obesity or Low Body Weight: a Systematic Review and Meta-Analysis

期刊: CARDIOVASCULAR DRUGS AND THERAPY, 2022; 36 (4)

Purpose Oral anticoagulants are crucial for preventing systemic thromboembolism in atrial fibrillation (AF), with guidelines preferring non-vitamin K ......

JIF:2.77

Low-dose Dasatinib Ameliorates Hypertrophic Cardiomyopathy in Noonan Syndrome with Multiple Lentigines

期刊: CARDIOVASCULAR DRUGS AND THERAPY, 2022; 36 (4)

Purpose Noonan syndrome with multiple lentigines (NSML) is an autosomal dominant disorder presenting with hypertrophic cardiomyopathy (HCM). Up to 85%......

JIF:2.77

K-80003 Inhibition of Macrophage Apoptosis and Necrotic Core Development in Atherosclerotic Vulnerable Plaques

期刊: CARDIOVASCULAR DRUGS AND THERAPY, 2022; 36 (6)

Purpose Macrophage apoptosis coupled with a defective phagocytic clearance of the apoptotic cells promotes plaque necrosis in advanced atherosclerosis......

JIF:2.77

Challenges in Optimizing Lipid Management in Women

期刊: CARDIOVASCULAR DRUGS AND THERAPY, 2022; 36 (6)

While there are physiologic differences in lipid metabolism in men and women, pharmacologic therapy is very effective in both with similar management ......

JIF:2.77

Implementation of Cholesterol-Lowering Therapy to Reduce Cardiovascular Risk in Persons Living with HIV

期刊: CARDIOVASCULAR DRUGS AND THERAPY, 2022; 36 (1)

The widespread availability of highly effective antiretroviral therapies has reduced mortality from opportunistic infections in persons living with HI......

JIF:2.77

Angio-Based Fractional Flow Reserve, Functional Pattern of Coronary Artery Disease, and Prediction of Percutaneous Coronary Intervention Result: a Proof-of-Concept Study

期刊: CARDIOVASCULAR DRUGS AND THERAPY, 2022; 36 (4)

Purpose Wire-based coronary physiology pullback performed before percutaneous coronary intervention (PCI) discriminates coronary artery disease (CAD) ......

JIF:2.77

Efficacy and Safety of the Fixed-Dose Versus Variable-Dose of 4-PCC for Vitamin K Antagonist Reversal: A Comprehensive Systematic Review and Meta-Analysis

期刊: CARDIOVASCULAR DRUGS AND THERAPY, 2022; 36 (3)

Background The optimal dosing strategy of four-factor prothrombin complex concentrate (4F-PCC) for vitamin K antagonists (VKAs) reversal is unknown. M......

JIF:2.77

Empagliflozin Disrupts a Tnfrsf12a-Mediated Feed Forward Loop That Promotes Left Ventricular Hypertrophy

期刊: CARDIOVASCULAR DRUGS AND THERAPY, 2022; 36 (4)

Purpose Although the cardioprotective benefits of sodium-glucose cotransporter 2 (SGLT2) inhibitors are now widely appreciated, the mechanisms underly......

JIF:2.77

A Bioinformatics Investigation into the Pharmacological Mechanisms of Sodium-Glucose Co-transporter 2 Inhibitors in Diabetes Mellitus and Heart Failure Based on Network Pharmacology

期刊: CARDIOVASCULAR DRUGS AND THERAPY, 2022; 36 (4)

Purpose Diabetes mellitus (DM) is a major risk factor for the development of heart failure (HF). Sodium-glucose co-transporter 2 (SGLT2) inhibitors ha......

JIF:2.77

Arrhythmia Recurrence After Atrial Fibrillation Ablation: Impact of Warfarin vs. Non-Vitamin K Antagonist Oral Anticoagulants

期刊: CARDIOVASCULAR DRUGS AND THERAPY, 2022; 36 (5)

Purpose Both warfarin and non-vitamin K antagonist oral anticoagulants (NOACs) have pleiotropic effects including anti-inflammatory and anti-fibrotic ......

JIF:2.77

Searching for Preclinical Models of Acute Decompensated Heart Failure: a Concise Narrative Overview and a Novel Swine Model

期刊: CARDIOVASCULAR DRUGS AND THERAPY, 2022; 36 (4)

Purpose Available animal models of acute heart failure (AHF) and their limitations are discussed herein. A novel and preclinically relevant porcine mo......

JIF:2.77

Rationale and Design of the H-REPLACE Study: Safety and Efficacy of LMWH Versus Rivaroxaban in ChinEse Patients HospitaLized with Acute Coronary SyndromE

期刊: CARDIOVASCULAR DRUGS AND THERAPY, 2022; 36 (1)

Background Acute coronary syndrome (ACS) is a serious and life-threatening condition. Anticoagulation during the acute phase of ACS is effective in re......

JIF:2.77

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