筛选条件 共查询到500条结果
排序方式
Development of a Transcriptional Activator-Like Effector Protein to Accurately Discriminate Single Nucleotide Difference

期刊: CHEMBIOCHEM, 2023; 24 (3)

Transcriptional activator-like effector (TALE), a DNA-binding protein, is widely used in genome editing. However, the recognition of the target sequen......

The Ketosynthase Domain Controls Chain Length in Mushroom Oligocyclic Polyketide Synthases

期刊: CHEMBIOCHEM, 2023; 24 (3)

The nonreducing iterative type I polyketide synthases (NR-PKSs) CoPKS1 and CoPKS4 of the webcap mushroom Cortinarius odorifer share 88 % identical ami......

Towards Selective Delivery of a Ruthenium(II) Polypyridyl Complex-Containing Bombesin Conjugate into Cancer Cells

期刊: CHEMBIOCHEM, 2023; 24 (4)

An increasing number of novel Ru(II) polypyridyl complexes have been successfully applied as photosensitizers (PSs) for photodynamic therapy (PDT). De......

Cell Wall-Denaturing Molecules for Plant Gene Modification

期刊: CHEMBIOCHEM, 2023; 24 (12)

Zwitterionic molecules, such as zwitterionic liquids (ZILs) and polypeptides (ZIPs), are attracting attention for application in new methods that can ......

Lysosomes Targeting pH Activable Imaging-Guided Photodynamic Agents

期刊: CHEMBIOCHEM, 2023; 24 (12)

Photodynamic therapy (PDT) is a photochemistry-based medical treatment combining light at a specific wavelength and a photosensitizer (PS) in the pres......

Characterization of an Unusual α-Oxoamine Synthase Off-Loading Domain from a Cyanobacterial Type I Fatty Acid Synthase

期刊: CHEMBIOCHEM, 2023; ()

Type I fatty acid synthases (FASs) are known from higher eukaryotes and fungi. We report the discovery of FasT, a rare type I FAS from the cyanobacter......

Failure, Success, and Future Direction of Alzheimer Drugs Targeting Amyloid-β Cascade: Pros and Cons of Chemical and Biological Modalities

期刊: CHEMBIOCHEM, 2023; 24 (19)

Alzheimer's disease (AD) is the most prevalent cause of dementia and has become a health concern worldwide urging for an effective therapeutic. The am......

Chemo-Enzymatic Fluorescence Labeling Of Genomic DNA For Simultaneous Detection Of Global 5-Methylcytosine And 5-Hydroxymethylcytosine

期刊: CHEMBIOCHEM, 2023; 24 (20)

5-Methylcytosine and 5-hydroxymethylcytosine are epigenetic modifications involved in gene regulation and cancer. We present a new, simple, and high-t......

A Cell-Free Multi-enzyme Cascade Reaction for the Synthesis of CDP-Glycerol

期刊: CHEMBIOCHEM, 2023; 24 (21)

CDP-glycerol is a nucleotide-diphosphate-activated version of glycerol. In nature, it is required for the biosynthesis of teichoic acid in Gram-positi......

Improved Cytotoxicity and Induced Apoptosis in HeLa Cells by Co-loading Vitamin E Succinate and Curcumin in Nano-MIL-88B-NH2

期刊: CHEMBIOCHEM, 2023; 24 (20)

One of the strategies for improved therapeutic effects in cancer therapy is combination chemotherapy. In this study, a flexible nano-MOF (Fe-MIL-88B-N......

Effect of Hyaluronic Acid on the Self-Assembly of a Dipeptide-Based Supramolecular Gel

期刊: CHEMBIOCHEM, 2023; ()

The combination of polymers and low molecular weight (LMW) compounds is a powerful approach to prepare new supramolecular materials. Here we prepare t......

Immunological Quantitation of the Glycation Site Lysine-414 in Serum Albumin in Human Plasma Samples by Indirect ELISA Using Highly Specific Monoclonal Antibodies

期刊: CHEMBIOCHEM, 2023; ()

Diabetes mellitus, a metabolic disorder that is characterized by elevated blood glucose levels, is common throughout the world and its prevalence is s......

Reflections on the Origin and Early Evolution of the Genetic Code

期刊: CHEMBIOCHEM, 2023; 24 (10)

Examination of the genetic code (GeCo) reveals that amino acids coded by (A/U) codons display a large functional spectrum and bind RNA whereas, except......

Heterologous Expression and Partial Characterization of a Putative Opine Dehydrogenase from a Metagenomic Sequence of Desulfohalobium retbaense

期刊: CHEMBIOCHEM, 2023; 24 (20)

The aim of this research was to prove the function of the putative opine dehydrogenase from Desulfohalobium retbaense and to characterize the enzyme i......

[Fe]-Hydrogenase, Cofactor Biosynthesis and Engineering

期刊: CHEMBIOCHEM, 2023; 24 (20)

[Fe]-hydrogenase catalyzes the heterolytic cleavage of H2 and reversible hydride transfer to methenyl-tetrahydromethanopterin. The iron-guanylylpyridi......

共500条页码: 1/34页15条/页