期刊: EJNMMI RADIOPHARMACY AND CHEMISTRY, 2023; 8 (1)
Background The molecular chaperone, Hsp90, is a key player in the protein quality control system that maintains homeostasis under cellular stress cond......
期刊: EJNMMI RADIOPHARMACY AND CHEMISTRY, 2023; 8 (1)
BackgroundPancreatic ductal adenocarcinoma (PDAC) continues to be a malignancy with an unmet clinical demand. Development of radioimmunoconjugates whi......
期刊: EJNMMI RADIOPHARMACY AND CHEMISTRY, 2023; 8 (1)
Background: Receptor interacting protein kinase 1 (RIPK1) is a serine/threonine kinase, which regulates programmed cell death and inflammation. Recent......
期刊: EJNMMI RADIOPHARMACY AND CHEMISTRY, 2023; 8 (1)
Background Recently it has been identified a short peptide that showed allosteric antagonism against C-C motif chemokine receptor 2 (CCR2) expressed o......
期刊: EJNMMI RADIOPHARMACY AND CHEMISTRY, 2023; 8 (1)
Background. Silver-111 is a promising beta--emitting radioisotope with ideal characteristics for targeted radionuclide therapy and associated single p......
期刊: EJNMMI RADIOPHARMACY AND CHEMISTRY, 2023; 8 (1)
BackgroundTargeted radionuclide therapy with [Lu-177]Lu-PSMA I&T (zadavotide guraxetan) has proven high efficacy and safety in treating patients w......
期刊: EJNMMI RADIOPHARMACY AND CHEMISTRY, 2023; 8 (1)
Background Lu-177-radiopharmaceuticals can contain the metastable impurity [Lu-177m]lutetium with a physical half-life of 160.4 days, in varying conce......
期刊: EJNMMI RADIOPHARMACY AND CHEMISTRY, 2023; 8 (1)
Background: The Affibody molecule, ABY-025, has demonstrated utility to detect human epidermal growth factor receptor 2 (HER2) in vivo, either radiola......
期刊: EJNMMI RADIOPHARMACY AND CHEMISTRY, 2023; 8 (1)
Background: Ketones are increasingly recognized as an important and possibly oxygen sparing source of energy in vital organs such as the heart, the br......
期刊: EJNMMI RADIOPHARMACY AND CHEMISTRY, 2023; 8 (1)
Background[Ga-68]Ga-PentixaFor is a promising radiotracer for positron emission tomography imaging of several human tumors overexpressing the chemokin......
期刊: EJNMMI RADIOPHARMACY AND CHEMISTRY, 2023; 8 (1)
Background: Reduced expression or impaired signalling of tropomyosin receptor kinases (Trk receptors) are found in a vast spectrum of CNS disorders. [......
期刊: EJNMMI RADIOPHARMACY AND CHEMISTRY, 2023; 8 (1)
Background: The [Lu-177]Lu-DOTA-TATE mediated peptide receptor radionuclide therapy (PRRT) of neuroendocrine tumors (NETs) is sometimes leading to tre......
期刊: EJNMMI RADIOPHARMACY AND CHEMISTRY, 2023; 8 (1)
Background: Platelet-derived growth factor receptor beta (PDGFR beta) is a receptor overexpressed on activated hepatic stellate cells (aHSCs). Positro......
期刊: EJNMMI RADIOPHARMACY AND CHEMISTRY, 2023; 8 (1)
Background: The positron emitting isotope fluorine-18 (F-18) possesses almost ideal physicochemical properties for the development of radiotracers for......