In this issue of Structure, Healy et al. discovered the PDLIM family of proteins as novel interactors of the sort-ing nexin SNX17, determined the NMR ......
CDK11 is a cyclin-dependent kinase that controls proliferation by regulating transcription, RNA splicing, and the cell cycle. As its activity is incre......
p120RasGAP is a multidomain GTPase-activating protein for Ras. The presence of two Src homology 2 do-mains in an SH2-SH3-SH2 module raises the possibi......
Subtilosin A is a sactipeptide bacteriocin produced by Bacillus subtilis strain 168, containing intramolecular thioether bonds and a head-to-tail macr......
In this issue of Structure, Kelso et al. present the crystal structure of the understudied cancer-associated cyclin-dependent kinase 11 (CDK11) bound ......
Emerging models of telomere and associated proteins in Tetrahymena have broadened our understanding of telomeric processes. In this issue of Structure......
Pseudomonas aeruginosa is an opportunistic pathogen that is responsible for thousands of deaths every year in the United States. P. aeruginosa virulen......
Orexin receptors are a family of G protein-coupled receptors that consist of two subtypes: orexin-1 receptors (OX1Rs) and OX2Rs. They are expressed th......
STARD3, a steroidogenic acute regulatory lipid transfer protein, was identified as a key xanthophyll-binding protein in the human retina. STARD3 and i......
Telomerase is crucial for telomere maintenance and genome integrity. The most salient feature of Tetrahy-mena telomerase is that its CST subcomplex (p......
The sorting nexin SNX17 controls endosomal recycling of transmembrane cargo proteins including integrins, the amyloid precursor protein, and lipoprote......
Despite their worldwide prevalence and association with human disease, the molecular bases of human as-trovirus (HAstV) infection and evolution remain......
In red-light sensing phytochromes, isomerization of the bilin chromophore triggers structural and dynamic changes across multiple domains, ultimately ......
Nucleosomes are symmetric structures. However, binding of linker histones generates an inherently asymmetric H1-nucleosome complex, and whether this a......
In this issue of Structure, Tettoni et al. present the structure and biochemical characterization of the fission yeast LAMTOR-Gtr complex, which media......
