Lipin 2/3 phosphatidic acid phosphatases maintain phospholipid homeostasis to regulate chylomicron synthesis

Zhang, PX; Csaki, LS; Ronquillo, E; Baufeld, LJ; Lin, JY; Gutierrez, A; Dwyer, JR; Brindley, DN; Fong, LG; Tontonoz, P; Young, SG; Reue, K

Reue, K (reprint author), Univ Calif Los Angeles, David Geffen Sch Med, Human Genet, Gonda 6357B,695 Charles E Young Dr South, Los Angeles, CA 90095 USA.

JOURNAL OF CLINICAL INVESTIGATION, 2019; 129 (1): 281

Abstract

The lipin phosphatidic acid phosphatase (PAP) enzymes are required for triacylglycerol (TAG) synthesis from glycerol 3-phosphate in most mammalian tis......

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