HIF-1 a represses the expression of the angiogenesis inhibitor thrombospondin-2

MacLauchlan, SC; Calabro, NE; Huang, Y; Krishna, M; Bancroft, T; Sharma, T; Yu, J; Sessa, WC; Giordano, F; Kyriakides, TR

Giordano, F (reprint author), Yale Univ, Sch Med, Sect Cardiovasc Med, Dept Internal Med, 10 Amistad Str 401C, New Haven, CT 06520 USA.; Kyriakides, TR (reprint author), Yale Univ, Sch Med, Dept Pathol, 10 Amistad Str 301C, New Haven, CT 06520 USA.

MATRIX BIOLOGY, 2018; 65 (): 45

Abstract

Thrombospondin-2 (TSP2) is a potent inhibitor of angiogenesis whose expression is dynamically regulated following injury. In the present study, it is ......

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