PHF19 promotes multiple myeloma tumorigenicity through PRC2 activation and broad H3K27me3 domain formation

Ren, ZH; Ahn, JH; Liu, HQ; Tsai, YH; Bhanu, NV; Koss, B; Allison, DF; Ma, AQ; Storey, AJ; Wang, P; Mackintosh, SG; Edmondson, RD; Groen, RWJ; Martens, AC; Garcia, BA; Tackett, AJ; Jin, J; Cai, L; Zheng, DY; Wang, GG

Wang, GG (reprint author), UNC Lineberger Canc Ctr, 450 West Dr,CB 7295, Chapel Hill, NC 27599 USA.

BLOOD, 2019; 134 (14): 1176

Abstract

Dysregulation of polycomb repressive complex 2 (PRC2) promotes oncogenesis partly through its enzymatic function for inducing trimethylation of histon......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索