Structure-Based Design of Scaffolds Targeting PDE10A by INPHARMA-NMR

Codutti, L; Grimaldi, M; Carlomagno, T

Carlomagno, T (reprint author), Leibniz Univ Hannover, Ctr Biomol Drug Res, Schneiderberg 38, D-30167 Hannover, Germany.; Carlomagno, T (reprint author), Leibniz Univ Hannover, Inst Organ Chem, Schneiderberg 38, D-30167 Hannover, Germany.; Carlomagno, T (

JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2017; 57 (6): 1488

Abstract

Phosphodiesterases (PDE) hydrolyze both cyclic AMP and GMP (cAMP/cGMP) and are responsible for the regulation of their levels in a multitude of cellul......

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