BPTF regulates growth of adult and pediatric high-grade glioma through the MYC pathway

Green, AL; DeSisto, J; Flannery, P; Lemma, R; Knox, A; Lemieux, M; Sanford, B; O'Rourke, R; Ramkissoon, S; Jones, K; Perry, J; Hui, X; Moroze, E; Balakrishnan, I; O'Neill, AF; Dunn, K; DeRyckere, D; Danis, E; Safadi, A; Gilani, A; Hubbell-Engler, B; Nuss, Z; Levy, JMM; Serkova, N; Venkataraman, S; Graham, DK; Foreman, N; Ligon, K; Jones, K; Kung, AL; Vibhakar, R

Green, AL (corresponding author), Univ Colorado, Morgan Adams Fdn Pediat Brain Tumor Res Program, Dept Pediat, Sch Med, Anschutz Med Campus,RC1-N,Mail Stop 8302, Aurora, CO 80045 USA.; Green, AL (corresponding author), Childrens Hosp Colorado, Ctr Canc & Blood Disorders, Aurora, CO 80045 USA.

ONCOGENE, 2020; 39 (11): 2305

Abstract

High-grade gliomas (HGG) afflict both children and adults and respond poorly to current therapies. Epigenetic regulators have a role in gliomagenesis,......

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