Bach2 attenuates IL-2R signaling to control Treg homeostasis and Tfr development

Zhang, H; Dai, D; Hu, QW; Yang, F; Xue, YS; Li, FB; Shen, N; Zhang, M; Huang, CX

Huang, CX (corresponding author), Shanghai Jiao Tong Univ, Fac Basic Med, Shanghai Inst Immunol, Sch Med, Shanghai 200025, Peoples R China.; Huang, CX (corresponding author), Shanghai Jiao Tong Univ, Fac Basic Med, Dept Immunol & Microbiol, Sch Med, Shanghai 200025, Peoples R China.; Zhang, M (corresponding author), Shanghai Jiao Tong Univ, Shanghai Gen Hosp, Dept Resp & Crit Care Med, Sch Med, Shanghai 200080, Peoples R China.

CELL REPORTS, 2021; 35 (6):

Abstract

Differentiation and homeostasis of Foxp3(+) regulatory T cells (Tregs) are tightly controlled by the interleukin-2 receptor (IL-2R) signaling, yet the......

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