Targeting FAM134B-mediated reticulophagy activates sorafenib-induced ferroptosis in hepatocellular carcinoma

Liu, ZQ; Ma, CL; Wang, Q; Yang, H; Lu, ZH; Bi, T; Xu, ZZ; Li, T; Zhang, L; Zhang, YJ; Liu, JF; Wei, XQ; Li, J

Li, J (通讯作者),Shandong Univ, Shandong Qianfoshan Hosp, Cheeloo Coll Med, Dept Hepatobiliary Surg, Jinan 250012, Shandong, Peoples R China.;Liu, JF (通讯作者),Shandong First Med Univ, Affiliated Hosp 1, Dept Hepatobiliary Surg, Jinan 250014, Shandong, Peoples R China.;Wei, XQ (通讯作者),Shandong First Med Univ, Jinan Maternal & Child Hlth Care Hosp, Dept Reprod Med, Jinan 250001, Shandong, Peoples R China.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2022; 589 (): 247

Abstract

Ferroptosis is a kind of cell death closely related to selective autophagy, such as ferritinophagy, lipophagy, clockophagy and chaperone-mediated auto......

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