NLRP3 inflammasome inhibitor INF39 attenuated NLRP3 assembly in macrophages

Shi, YH; Lv, Q; Zheng, MJ; Sun, HX; Shi, FS

Shi, FS (corresponding author), Zhejiang Univ, Coll Anim Sci, Dept Vet Med, Hangzhou 310058, Zhejiang, Peoples R China.

INTERNATIONAL IMMUNOPHARMACOLOGY, 2021; 92 ():

Abstract

INF39 is a nontoxic, irreversible, acrylate-based NLRP3 inhibitor and a further optimization of ethyl 2-((2chlorophenyl) hydroxyl) methyl) acrylate (I......

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